Whipworm: Differential Diagnoses & Workup

References

1. Kappus KK, Juranek DD, Roberts JM. Results of testing for intestinal parasites by state diagnostic laboratories, United States, 1987. MMWR CDC Surveill Summ. Dec 1991;40(4):25-45. [Medline].

2. Bethony J, Brooker S, Albonico M, Geiger SM, Loukas A, Diemert D. Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet. May 6 2006;367(9521):1521-32. [Medline].

3. Nascimento-Carvalho CM, de Fatima Gesteira M, Azul-Neto LS, Andrade MQ. Prolonged treatment with albendazole for massive trichuriasis infection. Pediatr Infect Dis J. Nov 2004;23(11):1070. [Medline].

4. Diaz E, Mondragon J, Ramirez E, Bernal R. Epidemiology and control of intestinal parasites with nitazoxanide in children in Mexico. Am J Trop Med Hyg. Apr 2003;68(4):384-5. [Medline]. [Full Text].

5. Gilles HM, Hoffman PS. Treatment of intestinal parasitic infections: a review of nitazoxanide. Trends Parasitol. Mar 2002;18(3):95-7. [Medline].

6. Pearson RD. Nitazoxanide As Treatment of Intestinal Parasites in Children. Curr Infect Dis Rep. Feb 2004;6(1):25-26. [Medline].

7. AAP. Trichuriasis (Whipworm infection). In: 2006 Red Book: Report of the Committee on Infectious Diseases. 27^th ed. Elk Grove Village, Ill: American Academy of Pediatrics; 2006:674-5.

8. Arruda LK, Santos AB. Immunologic responses to common antigens in helminthic infections and allergic disease. Curr Opin Allergy Clin Immunol. Oct 2005;5(5):399-402. [Medline].

9. Cooper PJ. Interactions between helminth parasites and allergy. Curr Opin Allergy Clin Immunol. Feb 2009;9(1):29-37. [Medline].

10. da Costa e Silva EJ, de Albuquerque SC. Trichuris trichiura. Pediatr Radiol. Feb 2007;37(2):239. [Medline].

11. Elliott DE, Summers RW, Weinstock JV. Helminths and the modulation of mucosal inflammation. Curr Opin Gastroenterol. Jan 2005;21(1):51-8. [Medline].

12. Ezeamama AE, Friedman JF, Acosta LP, et al. Helminth infection and cognitive impairment among Filipino children. Am J Trop Med Hyg. May 2005;72(5):540-8. [Medline]. [Full Text].

13. Eziefula AC, Brown M. Intestinal nematodes: disease burden, deworming and the potential importance of co-infection. Curr Opin Infect Dis. Oct 2008;21(5):516-22. [Medline].

14. Falcone FH, Pritchard DI. Parasite role reversal: worms on trial. Trends Parasitol. Apr 2005;21(4):157-60. [Medline].

15. Flisser A, Valdespino JL, Garcia-Garcia L, et al. Using national health weeks to deliver deworming to children: lessons from Mexico. J Epidemiol Community Health. Apr 2008;62(4):314-7. [Medline].

16. Fox LM, Furness BW, Haser JK, et al. Tolerance and efficacy of combined diethylcarbamazine and albendazole for treatment of Wuchereria bancrofti and intestinal helminth infections in Haitian children. Am J Trop Med Hyg. Jul 2005;73(1):115-21. [Medline]. [Full Text].

17. Goodman D, Haji HJ, Bickle QD, et al. A comparison of methods for detecting the eggs of Ascaris, Trichuris, and hookworm in infant stool, and the epidemiology of infection in Zanzibari infants. Am J Trop Med Hyg. Apr 2007;76(4):725-31. [Medline].

18. Grencis RK, Cooper ES. Enterobius, trichuris, capillaria, and hookworm including ancylostoma caninum. Gastroenterol Clin North Am. Sep 1996;25(3):579-97. [Medline].

19. Hall A, Hewitt G, Tuffrey V, de Silva N. A review and meta-analysis of the impact of intestinal worms on child growth and nutrition. Matern Child Nutr. Apr 2008;4 Suppl 1:118-236. [Medline].

20. Hamer D, Despommier D. Intestinal nematodes. In: Gorbach SL, Bartlett JG, Blacklow NR, eds. Infectious Diseases. 2^nd ed. Philadelphia, Pa: WB Saunders Co; 1998:2003-5.

21. Hotez PJ, Arora S, Bethony J, et al. Helminth infections of children: prospects for control. Adv Exp Med Biol. 2005;568:135-44. [Medline].

22. Hutchinson SE, Powell CA, Walker SP, et al. Nutrition, anaemia, geohelminth infection and school achievement in rural Jamaican primary school children. Eur J Clin Nutr. Nov 1997;51(11):729-35. [Medline].

23. [Best Evidence] Keiser J, Utzinger J. Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysis. JAMA. Apr 23 2008;299(16):1937-48. [Medline].

24. Lorenzetti R, Campo SM, Stella F, et al. An unusual endoscopic finding: Trichuris trichiura. Case report and review of the literature. Dig Liver Dis. Nov 2003;35(11):811-3. [Medline].

25. Markell EK. Intestinal nematode infections. Pediatr Clin North Am. Aug 1985;32(4):971-86. [Medline].

26. Medical Economics Company. Physicians' Desk Reference. 53^rd ed. Montvale, NJ: Medical Economics Co; 1999:1442, 3018.

27. Mukhopadhyay C, Wilson G, Chawla K, Vs B, Shivananda PG. A 6 year Geohelminth infection profile of children at high altitude in Western Nepal. BMC Public Health. Mar 27 2008;8:98. [Medline].

28. Quihui L, Valencia ME, Crompton DW, et al. Role of the employment status and education of mothers in the prevalence of intestinal parasitic infections in Mexican rural schoolchildren. BMC Public Health. 2006;6:225. [Medline]. [Full Text].

29. Reddy M, Gill SS, Kalkar SR, et al. Oral drug therapy for multiple neglected tropical diseases: a systematic review. JAMA. Oct 24 2007;298(16):1911-24. [Medline].

30. Stoltzfus RJ, Albonico M, Tielsch JM, et al. School-based deworming program yields small improvement in growth of Zanzibari school children after one year. J Nutr. Nov 1997;127(11):2187-93. [Medline].

31. Tang N, Luo NJ. Prevalence of parasites in kindergarten children. Int J Infect Dis. May 2005;9(3):178-9. [Medline].

32. Tinuade O, John O, Saheed O, et al. Parasitic etiology of childhood diarrhea. Indian J Pediatr. Dec 2006;73(12):1081-4. [Medline].

33. Tokmak N, Koc Z, Ulusan S, Koltas IS, Bal N. Computed tomographic findings of trichuriasis. World J Gastroenterol. Jul 14 2006;12(26):4270-2. [Medline].

34. Turner JD, Jackson JA, Faulkner H, et al. Intensity of intestinal infection with multiple worm species is related to regulatory cytokine output and immune hyporesponsiveness. J Infect Dis. Apr 15 2008;197(8):1204-12. [Medline].

35. Walden J. Parasitic diseases. Other roundworms. Trichuris, hookworm, and Strongyloides. Prim Care. Mar 1991;18(1):53-74. [Medline].

36. Wang LJ, Cao Y, Shi HN. Helminth infections and intestinal inflammation. World J Gastroenterol. Sep 7 2008;14(33):5125-32. [Medline].

37. Wani SA, Ahmad F, Zargar SA, Dar ZA, Dar PA, Tak H, et al. Soil-transmitted helminths in relation to hemoglobin status among school children of the Kashmir Valley. J Parasitol. Jun 2008;94(3):591-3. [Medline].

38. Xu LQ, Yu SH, Jiang ZX, et al. Soil-transmitted helminthiases: nationwide survey in China. Bull World Health Organ. 1995;73(4):507-13. [Medline].

Further Reading

Keywords

whipworm, anemia, ascaris, Nematoda, parasite, parasite infection, parasitic disease, rectal prolapse, trichuriasis, Trichuris dysentery syndrome, Trichuris trichiura, T trichiura

Contributor Information and Disclosures

Author

Robert W Tolan Jr, MD, Chief, Division of Allergy, Immunology and Infectious Diseases, The Children's Hospital at Saint Peter's University Hospital; Clinical Associate Professor of Pediatrics, Drexel University College of Medicine
Robert W Tolan Jr, MD is a member of the following medical societies: American Academy of Pediatrics, American Medical Association, American Society for Microbiology, American Society of Tropical Medicine and Hygiene, Infectious Diseases Society of America, Pediatric Infectious Diseases Society, Phi Beta Kappa, and Physicians for Social Responsibility
Disclosure: GlaxoSmithKline Honoraria Speaking and teaching; MedImmune Honoraria Consulting; MedImmune Honoraria Speaking and teaching; Merck Honoraria Speaking and teaching; Novartis Honoraria Speaking and teaching; sanofi pasteur Grant/research funds Unrestricted research grant; sanofi pasteur  Consulting; sanofi pasteur Honoraria Speaking and teaching; Tap Honoraria Speaking and teaching; Baxter Healthcare Honoraria Speaking and teaching

Coauthor(s)

Tina Slusher, MD, Assistant Professor, Department of Pediatrics, Section of Pediatric Critical Care, West Virginia University
Tina Slusher, MD is a member of the following medical societies: Society of Critical Care Medicine
Disclosure: Nothing to disclose.

Steven L Lanski, MD, Department of Pediatrics, Division of Pediatric Emergency Medicine, Assistant Professor, Emory University and Children's Healthcare of Atlanta at Egleston
Steven L Lanski, MD is a member of the following medical societies: American Academy of Pediatrics
Disclosure: Nothing to disclose.

Medical Editor

Ashir Kumar, MBBS, MD, FAAP, Professor, Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University; Consulting Staff, Department of Pediatrics, EW Sparrow Hospital
Ashir Kumar, MBBS, MD, FAAP is a member of the following medical societies: American Academy of Pediatrics, American Association of Physicians of Indian Origin, American Federation for Clinical Research, American Society for Microbiology, Infectious Diseases Society of America, and Pediatric Infectious Diseases Society
Disclosure: Nothing to disclose.

Pharmacy Editor

Mary L Windle, PharmD, Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy, Pharmacy Editor, eMedicine
Disclosure: Pfizer Inc Stock Investment from financial planner; Avanir Pharma Stock Investment from financial planner ; WebMD Salary and stock Employment and investment from financial planner

Managing Editor

Martin Weisse, MD, Program Director, Associate Professor, Department of Pediatrics, West Virginia University
Martin Weisse, MD is a member of the following medical societies: Ambulatory Pediatric Association, American Academy of Pediatrics, and Pediatric Infectious Diseases Society
Disclosure: Nothing to disclose.

CME Editor

Daniel Rauch, MD, FAAP, Director, Pediatric Hospitalist Program, Associate Professor, Department of Pediatrics, New York University School of Medicine
Daniel Rauch, MD, FAAP is a member of the following medical societies: Ambulatory Pediatric Association, American Academy of Pediatrics, and Society of Hospital Medicine
Disclosure: Baxter Honoraria Consulting; Pfizer Honoraria Consulting

Chief Editor

Russell W Steele, MD, Head, Division of Pediatric Infectious Diseases, Ochsner Children's Health Center; Clinical Professor, Department of Pediatrics, Tulane University School of Medicine
Russell W Steele, MD is a member of the following medical societies: American Academy of Pediatrics, American Association of Immunologists, American Pediatric Society, American Society for Microbiology, Infectious Diseases Society of America, Louisiana State Medical Society, Pediatric Infectious Diseases Society, Society for Pediatric Research, and Southern Medical Association
Disclosure: None None None