Sarcoidosis: Multimedia

References

1. Braun T, Siedek V, Assmann G, et al. [Sarcoidosis of lymph nodes in the submandibular compartment.]. HNO. Jul 1 2009;[Medline].

2. Ozdogan A, Acioglu E, Karaman E, Oz B, Musellim B. A difficult case: sarcoidosis of the middle ear. Am J Otolaryngol. Jul-Aug 2009;30(4):281-4. [Medline].

3. Milman N, Svendsen CB, Hoffmann AL. Health-related quality of life in adult survivors of childhood sarcoidosis. Respir Med. Jun 2009;103(6):913-8. [Medline].

4. Alhamad EH. The six-minute walk test in patients with pulmonary sarcoidosis. Ann Thorac Med. Apr 2009;4(2):60-4. [Medline].

5. Marcille R, McCarthy M, Barton JW, et al. Long-term outcome of pediatric sarcoidosis with emphasis on pulmonary status. Chest. Nov 1992;102(5):1444-9. [Medline].

6. de Boer JH, Sijssens KM, Smeekens AE, Rothova A. Keratitis and arthritis in children with sarcoidosis. Br J Ophthalmol. Jun 2009;93(6):835, 844. [Medline].

7. Hetherington S. Sarcoidosis in young children. Am J Dis Child. Jan 1982;136(1):13-5. [Medline].

8. Harada T, Nabeshima K, Matsumoto T, Akagi T, Fujita M, Watanabe K. Histological findings of the computed tomography halo in pulmonary sarcoidosis. Eur Respir J. Jul 2009;34(1):281-3. [Medline].

9. Lower EE, Baughman RP. The use of low dose methotrexate in refractory sarcoidosis. Am J Med Sci. Mar 1990;299(3):153-7. [Medline].

10. Gedalia A, Molina JF, Ellis GS Jr, et al. Low-dose methotrexate therapy for childhood sarcoidosis. J Pediatr. Jan 1997;130(1):25-9. [Medline].

11. [Guideline] Society of Nuclear Medicine. Procedure guideline for gallium scintigraphy in inflammation. Society of Nuclear Medicine. Jun 2004.

12. [Guideline] Epstein AE, DiMarco JP, Ellenbogen KA, et al. ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices) developed in collaboration with the American Association for Thoracic Surgery and Society of Thoracic Surgeons. J Am Coll Cardiol. May 27 2008;51(21):e1-62. [Medline].

13. [Guideline] Zimmerman RD, Seidenwurm DJ, Davis PC, et al. Orbits, vision, and visual loss. [online publication]. American College of Radiology (ACR). 2006.

14. Baculard A, Blanc N, Boule M, et al. Pulmonary sarcoidosis in children: a follow-up study. Eur Respir J. Apr 2001;17(4):628-35. [Medline]. [Full Text].

15. Baumann RJ, Robertson WC. Neurosarcoid presents differently in children than in adults. Pediatrics. Dec 2003;112(6 Pt 1):e480-6. [Medline]. [Full Text].

16. Bresnitz EA, Strom BL. Epidemiology of sarcoidosis. Epidemiol Rev. 1983;5:124-56. [Medline].

17. Burton CM, Pressler T, Milman N. Pulmonary sarcoidosis in a child with cystic fibrosis. Pediatr Pulmonol. May 2005;39(5):473-7. [Medline].

18. Dimitriades C, Shetty AK, Vehaskari M, et al. Membranous nephropathy associated with childhood sarcoidosis. Pediatr Nephrol. Jun 1999;13(5):444-7. [Medline].

19. du Bois RM. Corticosteroids in sarcoidosis: friend or foe?. Eur Respir J. Jul 1994;7(7):1203-9. [Medline].

20. Fink CW, Cimaz R. Early onset sarcoidosis: not a benign disease. J Rheumatol. Jan 1997;24(1):174-7. [Medline].

21. Gedalia A, Shetty AK, Ward K. The diagnostic value of MRI in children with sarcoidosis presenting with fever of unknown origin. J Pedatr Orthop. 1997;17:460-462.

22. Gedalia A, Shetty AK, Ward K, et al. Abdominal aortic aneurysm associated with childhood sarcoidosis. J Rheumatol. Apr 1996;23(4):757-9. [Medline].

23. Hafner R, Vogel P. Sarcoidosis of early onset. A challenge for the pediatric rheumatologist. Clin Exp Rheumatol. Nov-Dec 1993;11(6):685-91. [Medline].

24. Heyer CM, Lemburg SP, Kagel T, et al. Evaluation of chronic infectious interstitial pulmonary disease in children by low-dose CT-guided transthoracic lung biopsy. Eur Radiol. Jul 2005;15(7):1289-95. [Medline].

25. Heyer CM, Mueller KM, Seiffert P, et al. Pulmonary sarcoidosis in a 14-year-old boy diagnosed by low-dose CT-guided transthoracic lung biopsy. Pediatr Pulmonol. Mar 2006;41(3):269-74. [Medline].

26. Hoffman AL, Milman N, Byg KE. Childhood sarcoidosis in Denmark 1979-1994: incidence, clinical features and laboratory results at presentation in 48 children. Acta Pediatr Scand. 2004;93:30-36.

27. Hoover DL, Khan JA, Giangiacomo J. Pediatric ocular sarcoidosis. Surv Ophthalmol. Jan-Feb 1986;30(4):215-28. [Medline].

28. James DG, Kendig EL Jr. Childhood sarcoidosis. Sarcoidosis. Mar 1988;5(1):57-9. [Medline].

29. James DG, Neville E, Siltzbach LE. A worldwide review of sarcoidosis. Ann N Y Acad Sci. 1976;278:321-34. [Medline].

30. Johns CJ, Michele TM. The clinical management of sarcoidosis. A 50-year experience at the Johns Hopkins Hospital. Medicine (Baltimore). Mar 1999;78(2):65-111. [Medline].

31. Kendig EL Jr. The clinical picture of sarcoidosis in children. Pediatrics. Sep 1974;54(3):289-92. [Medline].

32. Kendig EL, Brummer DL. The prognosis of sarcoidosis in children. Chest. Sep 1976;70(03):351-3. [Medline].

33. Kunkel SL, Lukacs NW, Strieter RM, Chensue SW. Th1 and Th2 responses regulate experimental lung granuloma development. Sarcoidosis Vasc Diffuse Lung Dis. Sep 1996;13(2):120-8. [Medline].

34. Lower EE, Baughman RP. Prolonged use of methotrexate for sarcoidosis. Arch Intern Med. Apr 24 1995;155(8):846-51. [Medline].

35. Mallory SB, Paller AS, Ginsburg BC, et al. Sarcoidosis in children: differentiation from juvenile rheumatoid arthritis. Pediatr Dermatol. Dec 1987;4(4):313-9. [Medline].

36. Newman LS, Rose CS, Maier LA. Sarcoidosis. N Engl J Med. Apr 24 1997;336(17):1224-34. [Medline].

37. North AF Jr, Fink CW, Gibson WM, et al. Sarcoid arthritis in children. Am J Med. Apr 1970;48(4):449-55. [Medline].

38. Pattishall EN, Kendig EL Jr. Sarcoidosis in children. Pediatr Pulmonol. Sep 1996;22(3):195-203. [Medline].

39. Pattishall EN, Strope GL, Denny FW. Pulmonary function in children with sarcoidosis. Am Rev Respir Dis. Jan 1986;133(1):94-6. [Medline].

40. Pattishall EN, Strope GL, Spinola SM, Denny FW. Childhood sarcoidosis. J Pediatr. Feb 1986;108(2):169-77. [Medline].

41. Pinkston P, Bitterman PB, Crystal RG. Spontaneous release of interleukin-2 by lung T lymphocytes in active pulmonary sarcoidosis. N Engl J Med. Apr 7 1983;308(14):793-800. [Medline].

42. Schurmann M, Bein G, Kirsten D, et al. HLA-DQB1 and HLA-DPB1 genotypes in familial sarcoidosis. Respir Med. Apr 1998;92(4):649-52. [Medline].

43. Sharma OP. Vitamin D, calcium, and sarcoidosis. Chest. Feb 1996;109(2):535-9. [Medline].

44. Sheffield EA. Pathology of sarcoidosis. Clin Chest Med. Dec 1997;18(4):741-54. [Medline].

45. Shetty AK, Correa H, Galen W, Gedalia A. Pathological case of the month. Childhood sarcoidosis. Arch Pediatr Adolesc Med. Sep 1997;151(9):955-6. [Medline].

46. Shetty AK, Gedalia A. Sarcoidosis in children. Curr Probl Pediatr. May-Jun 2000;30(5):149-76. [Medline].

47. Shetty AK, Gedalia A. Sarcoidosis: a pediatric perspective. Clin Pediatr (Phila). Dec 1998;37(12):707-17. [Medline].

48. Shetty AK, Zganjar BE, Ellis GS Jr, et al. Low-dose methotrexate in the treatment of severe juvenile rheumatoid arthritis and sarcoid iritis. J Pediatr Ophthalmol Strabismus. May-Jun 1999;36(3):125-8. [Medline].

49. Singal A, Thami GP, Goraya JS. Scar sarcoidosis in childhood: case report and review of the literature. Clin Exp Dermatol. May 2005;30(3):244-6. [Medline].

50. Weinberg S, Bennett H, Weinstock I. Central nervous system manifestations of sarcoidosis in children. Case report and review. Clin Pediatr (Phila). Jul 1983;22(7):477-81. [Medline].

Further Reading

• Relevant clinical guidelines include the following:
  • Procedure guideline for gallium scintigraphy in inflammation ¹¹
  • 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices) ¹²
  • American College of Radiology Appropriateness Criteria for orbits, vision, and visual loss ¹³
• Relevant clinical trials include the following:
  • Stromal Gene Expression During Pulmonary Sarcoidosis
  • The Efficacy and Safety of CC-10004 in Chronic Cutaneous Sarcoidosis
  • Atorvastatin to Treat Pulmonary Sarcoidosis
  • Trial for the Diagnosis of Sarcoidosis (GRANULOMA)
• Related eMedicine topics include the following:
  • Sarcoidosis (Dermatology)
  • Sarcoidosis (Emergency Medicine)
  • Sarcoidosis (Ophthalmology)
  • Sarcoidosis (Pulmonology)
  • Sarcoidosis, Thoracic (Radiology)

Keywords

sarcoidosis, Besnier-Boeck-Schaumann disease, Besnier-Boeck-Schaumann syndrome, Boeck disease, Boeck's disease, Boeck sarcoid, Boeck's sarcoid, sarcoid, Schaumann syndrome, Schaumann's syndrome, sarcoid granulomas, tuberculosis, uveitis, polyarthritis, blindness, growth retardation, renal failure, glaucoma, pleural effusion, pneumothorax, pleural thickening, calcification, atelectasis, cor pulmonale, juvenile rheumatoid arthritis, scar sarcoidosis, erythema nodosum, Lofgren syndrome, nephrolithiasis, nephrocalcinosis, cardiac sarcoidosis, neurosarcoidosis, meningitis, seizures, hypopituitarism, diabetes insipidus, cerebellar ataxia, Heerfordt syndrome, pericarditis, myocarditis, intraventricular thrombosis, Mycobacterium tuberculosis, treatment, diagnosis

Contributor Information and Disclosures

Author

Avinash Shetty, MD, Department of Pediatrics, Division of Pediatric Infectious Diseases, Assistant Professor of Pediatrics, Wake Forest University School of Medicine
Avinash Shetty, MD is a member of the following medical societies: Ambulatory Pediatric Association, American Academy of Pediatrics, Infectious Diseases Society of America, and Pediatric Infectious Diseases Society
Disclosure: Nothing to disclose.

Coauthor(s)

Abraham Gedalia, MD, Head, Division of Pediatric Rheumatology, Professor of Pediatrics, Louisiana State University Health Sciences Center, Children's Hospital of New Orleans
Abraham Gedalia, MD is a member of the following medical societies: American Academy of Pediatrics and American College of Rheumatology
Disclosure: Nothing to disclose.

Medical Editor

Susanna A McColley, MD, Director of Cystic Fibrosis Center; Head, Division of Pulmonary Medicine; Associate Professor, Department of Pediatrics, Children's Memorial Medical Center of Chicago, Northwestern University
Susanna A McColley, MD is a member of the following medical societies: American Academy of Pediatrics, American College of Chest Physicians, American Sleep Disorders Association, and American Thoracic Society
Disclosure: Genentech Honoraria Speaking and teaching; Genentech Honoraria Consulting; Novartis Honoraria Consulting; Altus  Consulting fee Consulting; Axcan Scandi Consulting fee Consulting; Boston Scientific Consulting fee Consulting; Gilead  Speaking and teaching

Pharmacy Editor

Mary L Windle, PharmD, Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy, Pharmacy Editor, eMedicine
Disclosure: Pfizer Inc Stock Investment from financial planner; Avanir Pharma Stock Investment from financial planner ; WebMD Salary and stock Employment and investment from financial planner

Managing Editor

Charles Callahan, DO, Professor, Deputy Chief of Clinical Services, Walter Reed Army Medical Center
Charles Callahan, DO is a member of the following medical societies: American Academy of Pediatrics, American College of Chest Physicians, American College of Osteopathic Pediatricians, American Thoracic Society, Association of Military Surgeons of the US, and Christian Medical & Dental Society
Disclosure: Nothing to disclose.

CME Editor

Mary E Cataletto, MD, Associate Director, Division of Pediatric Pulmonology, Winthrop University Hospital; Professor of Clinical Pediatrics, State University of New York at Stony Brook; Director of Children's Sleep Services, Winthrop University Hospital
Mary E Cataletto, MD is a member of the following medical societies: American Academy of Pediatrics and American College of Chest Physicians
Disclosure: Shering Plough Pharmaceuticals Honoraria Consulting

Chief Editor

Michael R Bye, MD, Professor of Clinical Pediatrics, Division of Pulmonary Medicine, Columbia University College of Physicians and Surgeons; Attending Physician, Pediatric Pulmonary Medicine, Morgan Stanley Children's Hospital of New York Presbyterian, Columbia University Medical Center
Michael R Bye, MD is a member of the following medical societies: American Academy of Pediatrics, American College of Chest Physicians, and American Thoracic Society
Disclosure: Merck Honoraria Speaking and teaching