Pediatric Bronchiectasis Differential Diagnoses
- Author: Michael R Bye, MD; Chief Editor: Michael R Bye, MD more...
Bronchiectasis is a relatively uncommon condition that is often unsuspected in a child with previously diagnosed obstructive pulmonary disease, such as asthma. The clinician must remember that asthma does not cause digital clubbing. A child with asthma and clubbing must be further evaluated. The child with asthma who does not respond as expected to therapy should be further evaluated.
The identification of bronchiectasis in a child without a known underlying disorder should prompt efforts to determine the etiology of the bronchiectasis.
Singleton RJ; Valery PC; Morris P; Byrnes CA; Grimwood K; Redding G; Torzillo PJ; McCallum G; Chikoyak L; Mobberly C; Holman RC; Chang AB. Indigenous children from three countries with non-cystic fibrosis chronic suppurative lung disease/bronchiectasis. Pediatric Pulmonology. Feb 2013.
Sirmali M, Turut H, Kisacik E, et al. The relationship between time of admittance and complications in paediatric tracheobronchial foreign body aspiration. Acta Chir Belg. 2005 Nov-Dec. 105(6):631-4. [Medline].
Clark NS. Bronchiectasis in childhood. Br Med J. 1963 Jan 12. 5323:80-8. [Medline].
Weycker D, Edelsberg J, Oster G, Tino G. Prevalence and economic burden of bronchiectasis. Clin Pulm Med. 2006. 12:205.
Callahan CW. Bronchiectasis: abated or aborted?. Respiration. 2005 May-Jun. 72(3):225-6. [Medline].
Redding G, Singleton R, Lewis T, Martinez P, Butler J, Stamey D. Early radiographic and clinical features associated with bronchiectasis in children. Pediatr Pulmonol. 2004 Apr. 37(4):297-304. [Medline].
Field CE. Bronchiectasis. Third report on a follow-up study of medical and surgical cases from childhood. Arch Dis Child. 1969 Oct. 44(237):551-61. [Medline].
Karadag B, Karakoc F, Ersu R, et al. Non-cystic-fibrosis bronchiectasis in children: a persisting problem in developing countries. Respiration. 2005 May-Jun. 72(3):233-8. [Medline].
Morrissey BM, Harper RW. Bronchiectasis: sex and gender considerations. Clin Chest Med. 2004 Jun. 25(2):361-72. [Medline].
Field CE. Bronchiectasis in childhood. I. Clinical survey of 160 cases. Arch Dis Child. 1949. 4:21-46.
Twiss J, Stewart AW, Byrnes CA. Longitudinal pulmonary function of childhood bronchiectasis and comparison with cystic fibrosis. Thorax. 2006 May. 61(5):414-8. [Medline].
Akalin F, Koroglu TF, Bakac S, Dagli E. Effects of childhood bronchiectasis on cardiac functions. Pediatr Int. 2003 Apr. 45(2):169-74. [Medline].
Tsao PC, Lin CY. Clinical spectrum of bronchiectasis in children. Acta Paediatr Taiwan. 2002 Sep-Oct. 43(5):271-5.
Lai SH, Wong KS, Liao SL. Clinical analysis of bronchiectasis in Taiwanese children. Chang Gung Med J. 2004 Feb. 27(2):122-8. [Medline].
Edwards EA, Metcalfe R, Milne DG, Thompson J, Byrnes CA. Retrospective review of children presenting with non cystic fibrosis bronchiectasis: HRCT features and clinical relationships. Pediatr Pulmonol. 2003 Aug. 36(2):87-93. [Medline].
Pizzutto SJ; Grimwood K; Bauert P; Schutz KL; Yerkovich ST; Upham JW; Chang AB. Bronchoscopy contributes to the clinical management of indigenous children newly diagnosed with bronchiectasis. Pediatric Pulmonology. January 2013. 48:67-73.
Guran T; Ersu R; Karadag B; Karakoc F; Demirel GY; Hekim N; Dagli E. Withdrawal of inhaled steroids in chidlren with non-Cystic Fibrosis bronchiectasis. Journal of Clinical Pharmacy and Therapeutics. December 2008. 33:603-611.
Evans DJ, Bara AI, Greenstone M. Prolonged antibiotics for purulent bronchiectasis. Cochrane Database Syst Rev. 2003. CD001392. [Medline].
Hnin K, Nguyen C, Carson KV, Evans DJ, Greenstone M, Smith BJ. Prolonged antibiotics for non-cystic fibrosis bronchiectasis in children and adults. Cochrane Database Syst Rev. 2015 Aug 13. 8:CD001392. [Medline].
Davies G, Wilson R. Prophylactic antibiotic treatment of bronchiectasis with azithromycin. Thorax. 2004 Jun. 59(6):540-1. [Medline].
Anwar GA, Bourke SC, Afolabi G, et al. Effects of long-term low-dose azithromycin in patients with non-CF bronchiectasis. Respir Med. 2008 Oct. 102(10):1494-6. [Medline].
Rogers GB, Bruce KD, Martin ML, Burr LD, Serisier DJ. The effect of long-term macrolide treatment on respiratory microbiota composition in non-cystic fibrosis bronchiectasis: an analysis from the randomised, double-blind, placebo-controlled BLESS trial. Lancet Respir Med. 2014 Dec. 2 (12):988-96. [Medline].
[Guideline] Rosen MJ. Chronic cough due to tuberculosis and other infections: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan. 129(1 Suppl):197S-201S. [Medline].
Otgun I, Karnak I, Tanyel FC, et al. Surgical treatment of bronchiectasis in children. J Pediatr Surg. 2004 Oct. 39(10):1532-6. [Medline].
Beirne PA, Banner NR, Khaghani A, Hodson ME, Yacoub MH. Lung transplantation for non-cystic fibrosis bronchiectasis: analysis of a 13-year experience. J Heart Lung Transplant. 2005 Oct. 24(10):1530-5. [Medline].
Kellett F, Redfern J, Niven RM. Evaluation of nebulised hypertonic saline (7%) as an adjunct to physiotherapy in patients with stable bronchiectasis. Respir Med. 2005 Jan. 99(1):27-31. [Medline].