Pediatric Costochondritis Medication
- Author: Joseph P Garry, MD, FACSM, FAAFP; Chief Editor: Lawrence K Jung, MD more...
Medication Summary
NSAIDs provide analgesia for mild-to-moderate chest pain and may modulate the presumed inflammatory process. Purely analgesic drugs (eg, acetaminophen, tramadol hydrochloride) may suffice.
Nonsteroidal anti-inflammatory drugs
Class Summary
These provide analgesia and may play a role in controlling inflammation.
Ibuprofen (Motrin, Advil, Ibuprin)
Inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.
Naproxen (Aleve)
Available as OTC preparation and in prescription form; OTC preparation has faster onset of action, though limited duration of action. Prescription form is available in both pill and elixir forms and has a convenient bid-dosing schedule.
Analgesics
Class Summary
These may be used to relieve mild-to-moderate pain.
Acetaminophen (Tylenol)
May be used to relieve mild-to-moderate pain. Inhibits prostaglandin synthetase in the CNS by inhibiting cyclooxygenase.
Tramadol hydrochloride (Ultram)
Inhibits ascending pain pathways, altering perception of and response to pain. Also inhibits reuptake of norepinephrine and serotonin.
Proulx AM, Zryd TW. Costochondritis: diagnosis and treatment. Am Fam Physician. Sep 15 2009;80(6):617-20. [Medline].
[Guideline] Institute for Clinical Systems Improvement (ICSI). Diagnosis and treatment of chest pain and acute coronary syndrome (ACS). Bloomington (MN): Institute for Clinical Systems Improvement (ICSI); 2008 Oct.
Rumball JS, Lebrun CM, Di Ciacca SR, Orlando K. Rowing injuries. Sports Med. 2005;35(6):537-55. [Medline].
Rovetta G, Sessarego P, Monteforte P. Stretching exercises for costochondritis pain. G Ital Med Lav Ergon. Apr-Jun 2009;31(2):169-71. [Medline].
Aeschlimann A, Kahn MF. Tietze's syndrome: a critical review. Clin Exp Rheumatol. Jul-Aug 1990;8(4):407-12. [Medline].
Aspegren D, Hyde T, Miller M. Conservative treatment of a female collegiate volleyball player with costochondritis. J Manipulative Physiol Ther. May 2007;30(4):321-5. [Medline].
Brown RT. Costochondritis in adolescents. J Adolesc Health Care. Mar 1981;1(3):198-201. [Medline].
Brown RT. The adolescent with costochondritis. Compr Ther. Dec 1988;14(12):27-9. [Medline].
Driscoll DJ, Glicklich LB, Gallen WJ. Chest pain in children: a prospective study. Pediatrics. May 1976;57(5):648-51. [Medline].
Fam AG. Approach to musculoskeletal chest wall pain. Prim Care. Dec 1988;15(4):767-82. [Medline].
Feinstein RA, Daniel WA Jr. Chronic chest pain in children and adolescents. Pediatr Ann. Oct 1986;15(10):685-6, 691-4. [Medline].
Gregory PL, Biswas AC, Batt ME. Musculoskeletal problems of the chest wall in athletes. Sports Med. 2002;32(4):235-50. [Medline].
Harvard Womens Health Watch. Costochondritis: Not a heart attack but it feels like one. Harv Womens Health Watch. Mar 2003;10(7):6-7. [Medline].
Mendelson G, Mendelson H, Horowitz SF et al. Can (99m)-technitium methylene diphosphonate bone scan objectively document costochondritis?. Chest. 1997;111(6):1600-1602.
Mukamel M, Kornreich L, Horev G, Zeharia A, Mimouni M. Tietze's syndrome in children and infants. J Pediatr. Nov 1997;131(5):774-5. [Medline].
Pantell RH, Goodman BW Jr. Adolescent chest pain: a prospective study. Pediatrics. Jun 1983;71(6):881-7. [Medline].
Rowe BH, Dulberg CS, Peterson RG. Characteristics of children presenting with chest pain to a pediatric emergency department. CMAJ. Sep 1 1990;143(5):388-94. [Medline].
Selbst SM. Chest pain in children. Am Fam Physician. Jan 1990;41(1):179-86. [Medline].
Selbst SM. Chest pain in children. Pediatrics. Jun 1985;75(6):1068-70. [Medline].
Selbst SM, Ruddy RM, Clark BJ. Pediatric chest pain: a prospective study. Pediatrics. Sep 1988;82(3):319-23. [Medline].
Semble EL, Wise CM. Chest pain: a rheumatologist's perspective. South Med J. Jan 1988;81(1):64-8. [Medline].

