eMedicine Specialties > Pediatrics: General Medicine > Rheumatology

Weber-Christian Disease: Multimedia

Author: Moise L Levy, MD, Professor, Departments of Pediatrics and Dermatology, Baylor College of Medicine; Chief, Department of Dermatology, Texas Children's Hospital
Contributor Information and Disclosures

Updated: May 8, 2009

Multimedia

Standard posteroanterior chest radiograph reveals...Media file 1: Standard posteroanterior chest radiograph reveals extensive bilateral hilar and mediastinal lymph node enlargement not associated with a pulmonary abnormality in a patient with sarcoidosis.
Standard posteroanterior chest radiograph reveals...

Standard posteroanterior chest radiograph reveals extensive bilateral hilar and mediastinal lymph node enlargement not associated with a pulmonary abnormality in a patient with sarcoidosis.

Young male patient with fever and cough has a foc...Media file 2: Young male patient with fever and cough has a focal opacity in the left lower lobe that looks like a pneumonia. This is a case of primary tuberculosis.
Young male patient with fever and cough has a foc...

Young male patient with fever and cough has a focal opacity in the left lower lobe that looks like a pneumonia. This is a case of primary tuberculosis.

More on Weber-Christian Disease

Overview: Weber-Christian Disease
Differential Diagnoses & Workup: Weber-Christian Disease
Treatment & Medication: Weber-Christian Disease
Follow-up: Weber-Christian Disease
Multimedia: Weber-Christian Disease
References
Further Reading

References

  1. Weber EP. A case or relapsing nonsuppurative nodular panniculitis. Brit J Derm. 1925;37:301.

  2. Christian HA. Relapsing febrile nodular nonsuppurative panniculitis. Arch Intern Med. 1928;41:338.

  3. Haubrich WS. Weber and Christian of Weber-Christian disease. Gastroenterology. Apr 2008;134(4):912. [Medline].

  4. Valverde R, Rosales B, Ortiz-de Frutos FJ, Rodriguez-Peralto JL, Ortiz-Romero PL. Alpha-1-antitrypsin deficiency panniculitis. Dermatol Clin. Oct 2008;26(4):447-51, vi. [Medline].

  5. Wu F, Zou CC. Childhood Weber-Christian disease: clinical investigation and virus detection. Acta Paediatr. Nov 2007;96(11):1665-9. [Medline].

  6. Sharma AK, Sharma PR. Idiopathic lobular panniculitis (Weber Christian disease): a case report. Kathmandu Univ Med J (KUMJ). Apr-Jun 2006;4(2):243-5. [Medline].

  7. Abuzahra F, Kovacs S, Beermann T, et al. Treatment of relapsing idiopathic nodular panniculitis with clofazimine. Br J Dermatol. Mar 2005;152(3):582-3. [Medline].

  8. Eravelly J, Waters MF. Thalidomide in Weber-Christian disease. Lancet. Jan 29 1977;1(8005):251. [Medline].

  9. Freedberg IM, Eisen AZ, Wolff K. Panniculitis. In: Fitzpatrick's Dermatology in General Medicine. Vol 1. New York, NY: Mc-Graw Hill; 1999:1275-8.

  10. Hood AF, Kwan TH, Mihm ML, Jr. Panniculitis. In: Primer of Dermatopathology. Boston, MA: Little, Brown and Company; 1993:450.

  11. Lazarus GS. Panniculitis and Disorders of the Subcutaneous Fat. [Full Text].

  12. Lebwohl M. Panniculitis. In: Difficult Diagnoses in Dermatology. New York, NY: Churchill Livingstone; 1988:389-91.

  13. Lemley DE, Ferrans VJ, Fox LM, et al. Cardiac manifestations of Weber-Christian disease: report and review of the literature. J Rheumatol. May 1991;18(5):756-60. [Medline].

  14. Moschella SL, Hurley, HJ. Panniculitides. In: Dermatology. Vol 2. Philadelphia, PA: WB Saunders; 1985:1175-6.

  15. Panush RS, Yonker RA, Dlesk A, et al. Weber-Christian disease. Analysis of 15 cases and review of the literature. Medicine (Baltimore). May 1985;64(3):181-91. [Medline].

  16. Schuval SJ, Frances A, Valderrama E, et al. Panniculitis and fever in children. J Pediatr. Mar 1993;122(3):372-8. [Medline].

  17. Usuki K, Kitamura K, Urabe A, Takaku F. Successful treatment of Weber-Christian disease by cyclosporin A. Am J Med. Aug 1988;85(2):276-8. [Medline].

  18. White JW Jr, Winkelmann RK. Weber-Christian panniculitis: a review of 30 cases with this diagnosis. J Am Acad Dermatol. Jul 1998;39(1):56-62. [Medline].

  19. Winkelmann RK, Dahl PR, Perniciaro C, Dahl PM. Asteroid bodies and other cytoplasmic inclusions in necrobiotic xanthogranuloma with paraproteinemia. J Am Acad Dermatol. Jun 1998;38(6 Pt 1):967-70. [Medline].

Keywords

Weber-Christian disease, idiopathic lobular panniculitis, relapsing febrile nodular nonsuppurative panniculitis, nodular nonsuppurative panniculitis, Pfeifer-Weber-Christian syndrome, lupus panniculitis, factitial panniculitis, pancreatic disease, histiocytic cytophagic panniculitis, skin inflammation, skin rash, skin lesions, hepatomegaly, splenomegaly, treatment, diagnosis

Contributor Information and Disclosures

Author

Moise L Levy, MD, Professor, Departments of Pediatrics and Dermatology, Baylor College of Medicine; Chief, Department of Dermatology, Texas Children's Hospital
Moise L Levy, MD is a member of the following medical societies: American Academy of Dermatology, American Academy of Pediatrics, American Society for Laser Medicine and Surgery, Harris County Medical Society, Society for Investigative Dermatology, and Texas Medical Association
Disclosure: Nothing to disclose.

Pharmacy Editor

Mary L Windle, PharmD, Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy, Pharmacy Editor, eMedicine
Disclosure: Pfizer Inc Stock Investment from financial planner; Avanir Pharma Stock Investment from financial planner ; WebMD Salary and stock Employment and investment from financial planner

Managing Editor

Thomas JA Lehman, MD, FAAP, FACR, Clinical Professor of Pediatrics, Department of Pediatrics, Division of Pediatric Rheumatology, Weill-Cornell University; Chief, Hospital for Special Surgery
Thomas JA Lehman, MD, FAAP, FACR is a member of the following medical societies: PM American Allergy Society
Disclosure: Nothing to disclose.

CME Editor

Daniel Rauch, MD, FAAP, Director, Pediatric Hospitalist Program, Associate Professor, Department of Pediatrics, New York University School of Medicine
Daniel Rauch, MD, FAAP is a member of the following medical societies: Ambulatory Pediatric Association, American Academy of Pediatrics, and Society of Hospital Medicine
Disclosure: Baxter Honoraria Consulting

Chief Editor

Lawrence K Jung, MD, Chief, Division of Pediatric Rheumatology, Children's National Medical Center
Lawrence K Jung, MD is a member of the following medical societies: American Association for the Advancement of Science, American Association of Immunologists, American College of Rheumatology, Clinical Immunology Society, and New York Academy of Sciences
Disclosure: Nothing to disclose.

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