Ackee Fruit Toxicity Treatment & Management
- Author: Dave A Holson, MD, MBBS, MPH; Chief Editor: Timothy E Corden, MD more...
Traditionally, care in ackee fruit poisoning has been focused on relieving symptoms and providing supportive care with restoration of fluid, electrolyte, glucose, and pH balance.
- Administer a bolus of hypertonic dextrose solution followed by an infusion of 10% dextrose solution.
- Administer activated charcoal, which absorbs 100-1000 mg of poison per gram of carbon, if the patient presents within 4 hours of ingestion. If mental status is altered, consideration should be given to airway protection prior to charcoal use.
- Manage vomiting with antiemetics.
- Resuscitate volume-depleted patients with dextrose in normal saline.
- Manage seizures with benzodiazepines.
- If necessary patients sometime require intubation and ventilatory support.
- Animal studies have shown early glucose infusion with methylene blue reduces mortality associated with unripe ackee ingestion. Further testing in humans is needed.
- Theoretically, the supplementation of glycine, carnitine and riboflavin may be beneficial, but this has yet to be proven in the clinical setting.
See the list below:
- Contact the local poison control center.
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