Pediatric Monoamine Oxidase Inhibitor Toxicity Differential Diagnoses

  • Author: Soumya Ganapathy, MD; Chief Editor: Timothy E Corden, MD   more...
 
Updated: Mar 16, 2010
 
 

Differential Diagnoses

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Contributor Information and Disclosures
Author

Soumya Ganapathy, MD  Department of Emergency Medicine, Beverly Hospital

Soumya Ganapathy, MD is a member of the following medical societies: American College of Emergency Physicians

Disclosure: Nothing to disclose.

Coauthor(s)

Frank Anthony Maffei, MD, FAAP  Associate Professor of Pediatrics, Temple University School of Medicine; Medical Director, Pediatric Intensive Care Unit, Janet Weis Children's Hospital at Geisinger Health System

Frank Anthony Maffei, MD, FAAP is a member of the following medical societies: American Academy of Pediatrics

Disclosure: Nothing to disclose.

Specialty Editor Board

Michael E Mullins, MD  Assistant Professor, Division of Emergency Medicine, Washington University in St Louis School of Medicine; Attending Physician, Emergency Department, Barnes-Jewish Hospital

Michael E Mullins, MD is a member of the following medical societies: American Academy of Clinical Toxicology and American College of Emergency Physicians

Disclosure: Johnson & Johnson stock ownership None; Savient Pharmaceuticals stock ownership None

Mary L Windle, PharmD  Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Jeffrey R Tucker, MD  Assistant Professor, Department of Pediatrics, Division of Emergency Medicine, University of Connecticut School of Medicine, Connecticut Children's Medical Center

Disclosure: Merck Salary Employment

Paul D Petry, DO, FACOP, FAAP  Consulting Staff, Freeman Pediatric Care, Freeman Health System

Paul D Petry, DO, FACOP, FAAP is a member of the following medical societies: American Academy of Osteopathy, American Academy of Pediatrics, American College of Osteopathic Pediatricians, and American Osteopathic Association

Disclosure: Nothing to disclose.

Chief Editor

Timothy E Corden, MD  Associate Professor of Pediatrics, Co-Director, Policy Core, Injury Research Center, Medical College of Wisconsin; Associate Director, PICU, Children's Hospital of Wisconsin

Timothy E Corden, MD is a member of the following medical societies: American Academy of Pediatrics, Phi Beta Kappa, Society of Critical Care Medicine, and Wisconsin Medical Society

Disclosure: Nothing to disclose.

References

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  2. Hazell P. Depression in children and adolescents. Clin Evid (Online). Jan 7 2009;2009:[Medline].

  3. Jarrott B, Vajda FJ. The current status of monoamine oxidase and its inhibitors. Med J Aust. Jun 15 1987;146(12):634-8. [Medline].

  4. Larsen JK. MAO inhibitors: pharmacodynamic aspects and clinical implications. Acta Psychiatr Scand Suppl. 1988;345:74-80. [Medline].

  5. American Association of Poison Control Centers. AAPCC's Annual Reports. AAPC.org. Available at http://www.aapcc.org/dnn/NPDS/AnnualReports/tabid/125/Default.aspx. Accessed August 20, 2009.

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  15. Lucena MI, Carvajal A, Andrade RJ, Velasco A. Antidepressant-induced hepatotoxicity. Expert Opin Drug Saf. May 2003;2(3):249-62. [Medline].

  16. Rapaport MH. Dietary restrictions and drug interactions with monoamine oxidase inhibitors: the state of the art. J Clin Psychiatry. 2007;68 Suppl 8:42-6. [Medline].

  17. Sarko J. Antidepressants, old and new. A review of their adverse effects and toxicity in overdose. Emerg Med Clin North Am. Nov 2000;18(4):637-54. [Medline].

  18. Siberry GK, Iannone R, eds. The Harriet Lane Handbook. In: A Manual for Pediatric House Officers. 15th ed. Mosby-Year Book; 2000.

  19. Siderowf A, Kurlan R. Monoamine oxidase and catechol-O-methyltransferase inhibitors. Med Clin North Am. Mar 1999;83(2):445-67. [Medline].

  20. Tollefson GD. Monoamine oxidase inhibitors: a review. J Clin Psychiatry. Aug 1983;44(8):280-8. [Medline].

  21. [Guideline] University of Michigan Health System. Depression. Ann Arbor (MI): University of Michigan Health System; 2005 Oct.

  22. Wax P, Hoffman J, Keyes CD. Neuroleptics, lithium, and monoamine oxidase inhibitors. In: Rosen P, Barkin R, eds. Emergency Medicine. 3rd ed. 1992:2624-2628.

 
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