Circumcision 

  • Author: Carlos A Angel, MD; Chief Editor: Ted Rosenkrantz, MD   more...
 
Updated: Mar 25, 2011
 

Background

Circumcision of males involves removing the fold of skin that normally covers the glans penis.

Although no consensus exists among scholars regarding the origins of circumcision, some have suggested that this procedure likely originated in Egypt some 15,000 years ago and that its practice later spread throughout the world during prehistoric human migrations. Egyptian mummies and wall carvings discovered in the 19th century offer some of the earliest records of circumcision dating this procedure to at least 6000 years BC. However, other authors believe that circumcision developed independently in different cultures. For example, on his arrival to the New World, Columbus found that many of the natives were already circumcised.

Many cultures have historically used circumcision for hygienic reasons, for instance, as a rite of passage to manhood, as a mark of cultural identity (similar to a tattoo), or as a ceremonial offering to the gods. Ritual circumcisions in Middle Eastern cultures have been practiced for at least 3000 years. Late in the 19th century, this ancient ritual evolved into routine medical practice influenced by reports that associated it with miraculous cures for hernias, paralysis, epilepsy, insanity, masturbation, headache, strabismus, rectal prolapse hydrocephalus, clubfoot, asthma, enuresis, and gout.

Routine neonatal circumcision has become a controversial issue in the past 2 decades as many of the previously accepted medical indications have come under considerable scrutiny. Because neonatal circumcision poses both potential benefits and risks and because the procedure is not necessary for a child's well-being, the American Academy of Pediatrics (AAP) Task Force on Circumcision in its latest policy statement in 1999 affirms that "existing scientific evidence demonstrates potential benefits of newborn male circumcision; however, these data are not sufficient to recommend routine neonatal circumcision."[1] As a consequence, parents should be appropriately counseled so that they can make an informed choice and decide whether a circumcision is in the best interest of their child.

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Pathophysiology

The prepuce, a fold of skin that covers the glans penis, is lined up by an external keratinized layer and an internal mucosal layer. The pouch thus created can collect desquamated epithelial cells forming the so-called keratin pearls in infants and toddlers (which are not infectious in nature). In adolescence, cellular debris and local secretions collect in the form of smegma if the penis is not cleaned regularly. The prepuce provides protection to the glans from dryness and keratinization. Innervation of the prepuce is complex, the dorsal nerve of the penis and branches of the perineal nerve provide somatosensory input, whereas autonomic innervation comes primarily from the pelvic plexus.

Infant penis. Infant penis.
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Epidemiology

Frequency

United States

In the United States, accurate estimates of the rate of neonatal circumcisions are limited. The frequency of circumcision varies depending on geographic location, religious affiliation, and socioeconomic classification. One study showed differences in neonatal circumcision rates among racial and ethnic groups: 81% in whites, 65% in African-Americans, and 54% in Hispanics.

According to data from the National Hospital Discharge Survey, 1.2 million (65.3%) babies were circumcised in the United States in 1999, making this the highest rate of routine neonatal circumcision among developed nations. Healthcare coverage has and will continue to affect the rates of routine neonatal circumcision. As of 2004, 13 states had terminated Medicaid funding for neonatal circumcisions. At present, approximately 70% of obstetricians, 60% of family practitioners, and 35% of pediatricians practice newborn circumcision.

Sex

Circumcision applies only to male individuals.

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Contributor Information and Disclosures
Author

Carlos A Angel, MD  Associate Professor of Pediatrics, Division of Pediatric Surgery, University of Tennessee School of Medicine; Consulting Staff, East Tennessee Children's Hospital, East Tennessee Pediatric Surgery Group

Carlos A Angel, MD is a member of the following medical societies: American College of Surgeons, American Pediatric Surgical Association, British Association of Paediatric Surgeons, Children's Oncology Group, International Children's Continence Society, International Pediatric Endosurgery Group, New York Academy of Sciences, Society of Critical Care Medicine, and Texas Pediatric Society

Disclosure: Nothing to disclose.

Coauthor(s)

Michael Maddox, MD  Resident Physician, Department of Urology, Rhode Island Hospital, Brown University Medical School

Michael Maddox, MD is a member of the following medical societies: American Medical Student Association/Foundation and American Urological Association

Disclosure: Nothing to disclose.

Specialty Editor Board

Martin David Bomalaski, MD, FAAP  Pediatric Urologist, Alpine Urology

Martin David Bomalaski, MD, FAAP is a member of the following medical societies: Alpha Omega Alpha, American Academy of Pediatrics, and American Urological Association

Disclosure: Nothing to disclose.

Mary L Windle, PharmD  Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Harry P Koo, MD  Chairman of Urology Division and Director of Pediatric Urology, Professor of Surgery, Virginia Commonwealth University School of Medicine, Medical College of Virginia; Director of Urology, Children's Hospital of Richmond

Harry P Koo, MD is a member of the following medical societies: American Academy of Pediatrics, American College of Surgeons, and American Urological Association

Disclosure: Nothing to disclose.

Daniel Rauch, MD, FAAP  Director, Pediatric Hospitalist Program, Associate Professor, Department of Pediatrics, New York University School of Medicine

Daniel Rauch, MD, FAAP is a member of the following medical societies: Ambulatory Pediatric Association, American Academy of Pediatrics, and Society of Hospital Medicine

Disclosure: Baxter Honoraria Consulting

Chief Editor

Ted Rosenkrantz, MD  Professor, Departments of Pediatrics and Obstetrics/Gynecology, Division of Neonatal-Perinatal Medicine, University of Connecticut School of Medicine

Ted Rosenkrantz, MD is a member of the following medical societies: American Academy of Pediatrics, American Medical Association, American Pediatric Society, Connecticut State Medical Society, Eastern Society for Pediatric Research, and Society for Pediatric Research

Disclosure: Nothing to disclose.

Acknowledgments

The authors and editors of eMedicine gratefully acknowledge the contributions of previous author Santos Cantu Jr, MD, to the development and writing of this article.

Medscape Reference thanks Pamela I Ellsworth, MD, FACS, Associate Professor of Urology, The Warren Alpert Medical School of Brown University; Consulting Staff, University Urological Associates, for the video contributions to this article.

References
  1. Lannon CM, Bailey AGB, Fleischman AR. Circumcision policy statement. American Academy of Pediatrics. Task Force on Circumcision. Pediatrics. Mar 1999;103(3):686-93. [Medline].

  2. Wiswell TE, Hachey WE. Urinary tract infections and the uncircumcised state: an update. Clin Pediatr (Phila). Mar 1993;32(3):130-4. [Medline].

  3. Alanis MC, Lucidi RS. Neonatal circumcision: a review of the world's oldest and most controversial operation. Obstet Gynecol Surv. May 2004;59(5):379-95. [Medline].

  4. Weiss HA, Quigley MA, Hayes RJ. Male circumcision and risk of HIV infection in sub-Saharan Africa: a systematic review and meta-analysis. AIDS. 2000;14(15):2361-70. [Medline].

  5. Bailey RC, Neema S, Othieno R. Sexual behaviors and other HIV risk factors in circumcised and uncircumcised men in Uganda. J Acquir Immune Defic Syndr. 1999;Nov 1;22(3):294-301. [Medline].

  6. Wolbars AL. Circumcision and penile cancer. Lancet. 1932;1:150-3.

  7. Schoen EJ. Ignoring evidence of circumcision benefits. Pediatrics. 2006;118(1):385-7. [Medline].

  8. Berdeu D, Sauze L, Ha-Vinh P, Blum-Boisgard C. Cost-effectiveness analysis of treatments for phimosis: a comparison of surgical and medicinal approaches and their economic effect. BJU Int. Feb 2001;87(3):239-44. [Medline].

  9. Auvert B, Sobngwi-Tambekou J, Cutler E, Nieuwoudt M, Lissouba P, Puren A, et al. Effect of male circumcision on the prevalence of high-risk human papillomavirus in young men: results of a randomized controlled trial conducted in Orange Farm, South Africa. J Infect Dis. Jan 1 2009;199(1):14-9. [Medline].

  10. Cantu S Jr. Phimosis and paraphimosis. eMedicine Journal [serial online]. 2001. Available at: http://emedicine.medscape.com/article/777539-overview. [Full Text].

  11. Doyle SM, Kahn JG, Hosang N, Carroll PR. The impact of male circumcision on HIV transmission. J Urol. Jan 2010;183(1):21-6. [Medline].

  12. Mehta SD, Moses S, Agot K, Parker C, Ndinya-Achola JO, Maclean I, et al. Adult male circumcision does not reduce the risk of incident Neisseria gonorrhoeae, Chlamydia trachomatis, or Trichomonas vaginalis infection: results from a randomized, controlled trial in Kenya. J Infect Dis. Aug 1 2009;200(3):370-8. [Medline].

  13. Moses S. Male circumcision: a new approach to reducing HIV transmission. CMAJ. Oct 13 2009;181(8):E134-5. [Medline].

  14. Prais D, Shoov-Furman R, Amir J. Is ritual circumcision a risk factor for neonatal urinary tract infections?. Arch Dis Child. Mar 2009;94(3):191-4. [Medline].

  15. Roth DR, Gonzales ET Jr. Disorders of renal development and anomalies of the collecting system, bladder, penis, and scrotum. In: Oski FA, ed. Oski's Essential Pediatrics. 2nd ed. Wolters Kluwer; 1994:1763-5.

  16. Tobian AA, Serwadda D, Quinn TC, Kigozi G, Gravitt PE, Laeyendecker O, et al. Male circumcision for the prevention of HSV-2 and HPV infections and syphilis. N Engl J Med. Mar 26 2009;360(13):1298-309. [Medline].

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Infant penis.
Retracting the foreskin with a dorsal slit and marking the area to be incised. Video courtesy of Pamela I Ellsworth, MD.
Sleeve technique with electrocautery. Video courtesy of Pamela I Ellsworth, MD.
Suturing the mucosal collar to the penile shaft skin circumferentially. Video courtesy of Pamela I Ellsworth, MD.
Circumcision complete. Video courtesy of Pamela I Ellsworth, MD.
 
 
 
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