Background
Genital disorders are commonly encountered in the office of the primary care physician.[1] Meatal stenosis is a relatively common acquired condition occurring in 9%-10% of males who are circumcised. This disorder is characterized by an upward deflected, difficult-to-aim urinary stream and, occasionally, dysuria and urgent, frequent, and prolonged urination. Surgical meatotomy is curative.
Pathophysiology
After circumcision, a child who is not toilet-trained persistently exposes the meatus to urine, resulting in inflammation (ammoniacal dermatitis) and mechanical trauma as the meatus rubs against a wet diaper. This causes the loss of the delicate epithelial lining of the distal urethra. This loss may result in adherence of the epithelial lining at the ventral side, leaving a pinpoint orifice at the tip of the glans. Because this condition is exceedingly rare in uncircumcised children, circumcision is believed to be the most important causative factor of meatal stenosis.
Another hypothetical cause of this condition is ischemia due to damage to the frenular artery during circumcision, resulting in poor blood supply to the meatus and subsequent stenosis. In a prospective study of circumcised boys, Van Howe (2006) found meatal stenosis in 24 of 239 (7.29%) children older than 3 years, making meatal stenosis the most common complication of circumcision.[2]
Epidemiology
Frequency
International
Meatal stenosis affects 9%-10% of males who are circumcised.
Mortality/Morbidity
Meatal stenosis carries no risk of mortality.
Morbidity is limited to the clinical symptoms and complications of surgical repair, including bleeding, infection, and recurrence.
Race
Meatal stenosis has no racial predilection. The condition can occur in circumcised males independent of ethnicity.
Sex
Meatal stenosis occurs only in males.
Age
Children who are not toilet-trained are more prone to develop meatal stenosis after circumcision because of exposure of the meatus to urine in diapers. Most children who are toilet-trained can verbalize their difficulties during micturition to their caregivers.
Joudi M, Fathi M, Hiradfar M. Incidence of asymptomatic meatal stenosis in children following neonatal circumcision. J Pediatr Urol. Oct 2011;7(5):526-8. [Medline].
Van Howe RS. Incidence of meatal stenosis following neonatal circumcision in a primary care setting. Clin Pediatr (Phila). Jan-Feb 2006;45(1):49-54. [Medline].
Litvak AS, Morris JA, McRoberts JW. Normal size of the urethral meatus in boys. J Urol. Jun 1976;115(6):736-7. [Medline].
Gargollo PC, Kozakewich HP, Bauer SB, et al. Balanitis xerotica obliterans in boys. J Urol. Oct 2005;174(4 Pt 1):1409-12. [Medline].
Brown MR, Cartwright PC, Snow BW. Common office problems in pediatric urology and gynecology. Pediatr Clin North Am. Oct 1997;44(5):1091-115. [Medline].
Smith C, Smith DP. Office pediatric urologic procedures from a parental perspective. Urology. Feb 2000;55(2):272-6. [Medline].
Frank JD, Pocock RD, Stower MJ. Urethral strictures in childhood. Br J Urol. Dec 1988;62(6):590-2. [Medline].
Garat JM, Chechile G, Algaba F, Santaularia JM. Balanitis xerotica obliterans in children. J Urol. Aug 1986;136(2):436-7. [Medline].
Persad R, Sharma S, McTavish J, et al. Clinical presentation and pathophysiology of meatal stenosis following circumcision. Br J Urol. Jan 1995;75(1):91-3. [Medline].
Sijstermans K, Hack WW, Bos SD, van der Horst HJ. [Urethral meatal stenosis in boys easily overlooked]. Ned Tijdschr Geneeskd. Dec 10 2005;149(50):2765-9. [Medline].
Stenram A, Malmfors G, Okmian L. Circumcision for phimosis: a follow-up study. Scand J Urol Nephrol. 1986;20(2):89-92. [Medline].

