Acquired Angioedema Differential Diagnoses

  • Author: Ru'aa Al Harithy, MBBS, FRCPC; Chief Editor: William D James, MD   more...
 
Updated: Jan 26, 2012
 
 

Diagnostic Considerations

Other disorders to consider in the diagnosis of acquired angioedema are ACE inhibitor–induced angioedema, episodic angioedema with angioedema, and cold urticaria.

Go to Angioedema, Pediatric Angioedema, Emergent Treatment of Angioedema, and Hereditary Angioedema for complete information on this topic.

Differential Diagnoses

Proceed to Workup
 
 
Contributor Information and Disclosures
Author

Ru'aa Al Harithy, MBBS, FRCPC  Clinical Fellow in Laser and Cosmetic Dermatology, Division of Dermatology, SunnyBrook Hospital, University of Toronto Faculty of Medicine, Canada

Ru'aa Al Harithy, MBBS, FRCPC is a member of the following medical societies: American Academy of Dermatology and Canadian Dermatology Association

Disclosure: Nothing to disclose.

Coauthor(s)

Warren R Heymann, MD  Head, Division of Dermatology, Professor, Department of Internal Medicine, University of Medicine and Dentistry of New Jersey-New Jersey Medical School

Warren R Heymann, MD is a member of the following medical societies: American Academy of Dermatology, American Society of Dermatopathology, and Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Amanda T Moon, MD  Resident Physician, Department of Dermatology, University of Rochester, Strong Memorial Hospital

Amanda T Moon, MD, is a member of the following medical societies: American Academy of Dermatology, American Medical Association, American Medical Student Association/Foundation, and Society for Pediatric Dermatology

Disclosure: Nothing to disclose.

Chief Editor

William D James, MD  Paul R Gross Professor of Dermatology, Vice-Chairman, Residency Program Director, Department of Dermatology, University of Pennsylvania School of Medicine

William D James, MD is a member of the following medical societies: American Academy of Dermatology and Society for Investigative Dermatology

Disclosure: Elsevier Royalty Other

Additional Contributors

Paul Krusinski, MD Director of Dermatology, Fletcher Allen Health Care; Professor, Department of Internal Medicine, University of Vermont College of Medicine

Paul Krusinski, MD is a member of the following medical societies: American Academy of Dermatology, American College of Physicians, and Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Kathleen M Rossy, MD Staff Physician, Department of Dermatology, New York Medical College, Metropolitan Hospital

Disclosure: Nothing to disclose.

Robert A Schwartz, MD, MPH Professor and Head, Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, University of Medicine and Dentistry of New Jersey-New Jersey Medical School

Robert A Schwartz, MD, MPH is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American College of Physicians, and Sigma Xi

Disclosure: Nothing to disclose.

Michael J Wells, MD Associate Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine

Michael J Wells, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, and Texas Medical Association

Disclosure: Nothing to disclose.

References
  1. Caldwell JR, Ruddy S, Schur PH, Austen KF. Acquired C1 inhibitor deficiency in lymphosarcoma. Clin Immunol Immunopathol. 1972;1:39-52.

  2. Caballero T, Baeza ML, Cabañas R, et al. Consensus statement on the diagnosis, management, and treatment of angioedema mediated by bradykinin. Part I. Classification, epidemiology, pathophysiology, genetics, clinical symptoms, and diagnosis. J Investig Allergol Clin Immunol. 2011;21(5):333-47; quiz follow 347. [Medline].

  3. Cugno M, Zanichelli A, Foieni F, Caccia S, Cicardi M. C1-inhibitor deficiency and angioedema: molecular mechanisms and clinical progress. Trends Mol Med. Feb 2009;15(2):69-78. [Medline].

  4. Cugno M, Castelli R, Cicardi M. Angioedema due to acquired C1-inhibitor deficiency: a bridging condition between autoimmunity and lymphoproliferation. Autoimmun Rev. Dec 2008;8(2):156-9. [Medline].

  5. Banerji A, Sheffer AL. The spectrum of chronic angioedema. Allergy Asthma Proc. Jan-Feb 2009;30(1):11-6. [Medline].

  6. Cicardi M, Zanichelli A. Acquired angioedema. Allergy Asthma Clin Immunol. Jul 28 2010;6(1):14. [Medline]. [Full Text].

  7. Bouillet-Claveyrolas L, Ponard D, Drouet C, Massot C. Clinical and biological distinctions between type I and type II acquired angioedema. Am J Med. Oct 1 2003;115(5):420-1. [Medline].

  8. Levi M, Hack CE, van Oers MH. Rituximab-induced elimination of acquired angioedema due to C1-inhibitor deficiency. Am J Med. Aug 2006;119(8):e3-5. [Medline].

  9. Ziakas PD, Giannouli S, Psimenou E, Evangelia K, Tzioufas AG, Voulgarelis M. Acquired angioedema: a new target for rituximab?. Haematologica. Aug 2004;89(8):ELT13. [Medline].

  10. Rottem M, Mader R. Successful use of etanercept in acquired angioedema in a patient with psoriatic arthritis. J Rheumatol. Jan 2010;37(1):209. [Medline].

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Angioedema secondary to ACE inhibitors.
 
 
 
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