Dermographism Urticaria Workup
- Author: Simone Laube, MD, MRCP; Chief Editor: Dirk M Elston, MD more...
Laboratory Studies
- The results from hematological and biochemical screening tests are normal. In some patients, an increase in blood histamine levels is seen after experimental scratching.
Procedures
- The diagnosis is usually made by observing the clinical response after using moderate pressure to stroke or gently scratch the skin. The site is important because areas protected from regular pressure and environmental influences, such as the back, are more reactive than more exposed areas, such as the buttocks and limbs.
- A dermographometer (spring-loaded stylus) can be used to apply graded, reproducible pressure (eg, 3600 g/cm2) and record skin responses. It is mostly limited to research settings.
Histologic Findings
- Biopsy specimens show dermal edema with a few perivascular mononuclear cells.
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