eMedicine Specialties > Dermatology > Benign Neoplasms
Dermatosis Papulosa Nigra: Differential Diagnoses & Workup
Updated: Feb 19, 2009
- Overview
- Differential Diagnoses & Workup
- Treatment & Medication
- Follow-up
Differential Diagnoses
Nevi, Melanocytic
Seborrheic Keratosis
Other Problems to Be Considered
Acrochordons
Adenoma sebaceum
Workup
Histologic Findings
Lesions of dermatosis papulosa nigra have the histologic appearance of seborrheic keratoses; they display hyperkeratosis, irregular acanthosis, keratin-filled invaginations of the epidermis (horn cysts), and marked hyperpigmentation of the basal layer. Although most lesions are of the acanthotic type and show thick interwoven tracts of epidermal cells, they may have a reticulated pattern in which the tracts consist of a double row of basaloid cells.
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Differential Diagnoses & Workup: Dermatosis Papulosa Nigra |
| Treatment & Medication: Dermatosis Papulosa Nigra |
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References
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Hairston MA Jr, Reed RJ, Derbes VJ. Dermatosis papulosa nigra. Arch Dermatol. May 1964;89:655-8. [Medline].
Kauh YC, McDonald JW, Rapaport JA, Ruschak PJ, Luscombe HA. A surgical approach for dermatosis papulosa nigra. Int J Dermatol. Dec 1983;22(10):590-2. [Medline].
Schweiger ES, Kwasniak L, Aires DJ. Treatment of dermatosis papulosa nigra with a 1064 nm Nd:YAG laser: report of two cases. J Cosmet Laser Ther. Jun 2008;10(2):120-2. [Medline].
Carter EL, Coppola CA, Barsanti FA. A randomized, double-blind comparison of two topical anesthetic formulations prior to electrodesiccation of dermatosis papulosa nigra. Dermatol Surg. Jan 2006;32(1):1-6. [Medline].
Andrews GC, et al. Andrews' Diseases of the Skin. 8th ed. Philadelphia, Pa: WB Saunders; 1990:752.
Elder D, et al. Lever's Histopathology of the Skin. 8th ed. Philadelphia, Pa: Lippincott-Raven; 1997:693.
Moschella SL, Hurley HJ. Dermatology. Philadelphia, Pa: WB Saunders; 1992:2162-3.
Rook A, Wilkinson DS, Ebling FJG. Textbook of Dermatology. Vol 2. Oxford, England: Blackwell Scientific; 1998:1660-1.
Further Reading
Keywords
dermatosis papulosa nigra, DPN, hyperpigmented papules, facial papules, seborrheic keratosis
Differential Diagnoses & Workup: Dermatosis Papulosa Nigra