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Elastofibroma Treatment & Management

  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
Updated: Jun 10, 2016

Surgical Care

Complete local surgical excision is the treatment of choice in symptomatic patients or if malignancy cannot be excluded.[41] It can be well-controlled by radical surgery.[13] Recurrence after surgery is unusual.[42] Spontaneous regression has been observed without treatment. Because malignant transformation has not been described, asymptomatic lesions need not be excised.[43] In fact, surgical resection should be limited to those who are symptomatic, as the incidence of postoperative complications is high.[44, 45]


Long-Term Monitoring

Because elastofibromas are benign neoplasms, no long-term follow-up care is necessary.

Contributor Information and Disclosures

Robert A Schwartz, MD, MPH Professor and Head of Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, Rutgers New Jersey Medical School; Visiting Professor, Rutgers University School of Public Affairs and Administration

Robert A Schwartz, MD, MPH is a member of the following medical societies: Alpha Omega Alpha, New York Academy of Medicine, American Academy of Dermatology, American College of Physicians, Sigma Xi

Disclosure: Nothing to disclose.


Sonja Stander, MD Staff Physician, Department of Dermatology, University-Hospital Muenster, Germany

Disclosure: Nothing to disclose.

Specialty Editor Board

Richard P Vinson, MD Assistant Clinical Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine; Consulting Staff, Mountain View Dermatology, PA

Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Texas Medical Association, Association of Military Dermatologists, Texas Dermatological Society

Disclosure: Nothing to disclose.

Jeffrey Meffert, MD Associate Clinical Professor of Dermatology, University of Texas School of Medicine at San Antonio

Jeffrey Meffert, MD is a member of the following medical societies: American Academy of Dermatology, American Medical Association, Association of Military Dermatologists, Texas Dermatological Society

Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Additional Contributors

Kathryn Schwarzenberger, MD Associate Professor of Medicine, Division of Dermatology, University of Vermont College of Medicine; Consulting Staff, Division of Dermatology, Fletcher Allen Health Care

Kathryn Schwarzenberger, MD is a member of the following medical societies: Women's Dermatologic Society, American Contact Dermatitis Society, Medical Dermatology Society, Dermatology Foundation, Alpha Omega Alpha, American Academy of Dermatology

Disclosure: Nothing to disclose.


Thomas Schwarz, MD Vice Chairman, Professor, Department of Dermatology, University of Kiel, Germany

Thomas Schwarz, MD is a member of the following medical societies: American Academy of Dermatology, American Association of Immunologists, and Society for Investigative Dermatology

Disclosure: Nothing to disclose.

  1. Jarvi O, Saxen E. Elastofibroma dorse. Acta Pathol Microbiol Scand Suppl. 1961. 51(Suppl 144):83-4. [Medline].

  2. Hisaoka M, Hashimoto H. Elastofibroma: clonal fibrous proliferation with predominant CD34-positive cells. Virchows Arch. 2006 Feb. 448(2):195-9. [Medline].

  3. Shimizu S, Yasui C, Tateno M, et al. Multiple elastofibromas. J Am Acad Dermatol. 2004 Jan. 50(1):126-9. [Medline].

  4. Di Vito A, Scali E, Ferraro G, Mignogna C, Presta I, Camastra C, et al. Elastofibroma dorsi: a histochemical and immunohistochemical study. Eur J Histochem. 2015 Feb 19. 59 (1):2459. [Medline].

  5. Hernandez JL, Rodriguez-Parets JO, Valero JM, et al. High-resolution genome-wide analysis of chromosomal alterations in elastofibroma. Virchows Arch. 2010 Apr 27. [Medline].

  6. Nishio JN, Iwasaki H, Ohjimi Y, et al. Gain of Xq detected by comparative genomic hybridization in elastofibroma. Int J Mol Med. 2002 Sep. 10(3):277-80. [Medline].

  7. Alberghini M, Bacchini P, Pignatti G, et al. Histochemical and ultrastructural study of an elastofibroma dorsi coexisting with a high grade spindle cell sarcoma. Eur J Histochem. 2004 Apr-Jun. 48(2):173-8. [Medline].

  8. Alberghini M, Pignatti G, Zanella L, et al. Elastofibroma associated with high grade leiomyosarcoma of the soft tissues: a light and ultrastructural study of one case. J Submicrosc Cytol Pathol. 2003 Jan. 35(1):43-8. [Medline].

  9. Gun BD, Bahadir B, Behzatoglu K, Gun MO, Ozdamar SO. Elastofibroma: a clinicopathologic and immunohistochemical study of seven cases and literature review. APMIS. 2007 Feb. 115(2):115-9. [Medline].

  10. Chandrasekar CR, Grimer RJ, Carter SR, et al. Elastofibroma dorsi: an uncommon benign pseudotumour. Sarcoma. 2008. 2008:756565. [Medline].

  11. Blumenkrantz Y, Bruno GL, Gonzalez CJ, et al. Characterization of Elastofibroma Dorsi with (18)FDG PET/CT: a retrospective study. Rev Esp Med Nucl. 2011 Apr 3. [Medline].

  12. Hocar O, Buffard V, Ortonne N, Bagot M. [Bilateral elastofibroma dorsi]. Ann Dermatol Venereol. 2012 Jan. 139(1):41-5. [Medline].

  13. Lococo F, Cesario A, Mattei F, Petrone G, Vita LM, Petracca-Ciavarella L, et al. Elastofibroma dorsi: clinicopathological analysis of 71 cases. Thorac Cardiovasc Surg. 2013 Apr. 61(3):215-22. [Medline].

  14. Nonaka CF, Rego DM, Miguel MC, de Souza LB, Pinto LP. Elastofibromatous change of the oral mucosa: case report and literature review. J Cutan Pathol. 2010 Oct. 37(10):1067-71. [Medline].

  15. Schwarz T, Oppolzer G, Duschet P, Bruckler B, Gschnait F. Ulcerating elastofibroma dorsi. J Am Acad Dermatol. 1989 Nov. 21(5 Pt 2):1142-4. [Medline].

  16. Daigeler A, Vogt PM, Busch K, et al. Elastofibroma dorsi--differential diagnosis in chest wall tumours. World J Surg Oncol. 2007 Feb 5. 5:15. [Medline].

  17. Cavallasca JA, Sohn DI, Borgia AR, Maliandi MD, Musuruana JL. Elastofibroma dorsi: Review of 4 cases. Reumatol Clin. 2012 Mar 19. [Medline].

  18. Mirra JM, Straub LR, Jarvi OH. Elastofibroma of the deltoid. A case report. Cancer. 1974 Jan. 33(1):234-8. [Medline].

  19. De Nictolis M, Goteri G, Campanati G, Prat J. Elastofibrolipoma of the mediastinum. A previously undescribed benign tumor containing abnormal elastic fibers. Am J Surg Pathol. 1995 Mar. 19(3):364-7. [Medline].

  20. Manchandu R, Foote J, Alawi F. Elastofibroma presenting as an oral soft tissue mass. J Oral Pathol Med. 2008 Feb. 37(2):125-6. [Medline].

  21. Majo J, Gracia I, Doncel A, Valera M, Nunez A, Guix M. Elastofibroma dorsi as a cause of shoulder pain or snapping scapula. Clin Orthop Relat Res. 2001 Jul. 200-4. [Medline].

  22. Potter TJ, Summerlin DJ, Rodgers SF. Elastofibroma: the initial report in the oral mucosa. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Jan. 97(1):64-7. [Medline].

  23. Hsu JK, Cavanagh HD, Green WR. An unusual case of elastofibroma oculi. Cornea. 1997 Jan. 16(1):112-9. [Medline].

  24. Smith HG, Hannay J, Thway K, Messiou C, Smith M, Strauss DC, et al. Elastofibroma dorsi: The clunking tumour that need not cause alarm. Ann R Coll Surg Engl. 2016 Mar. 98 (3):208-11. [Medline].

  25. Erkilic S, Kocer NE, Sivrikoz C. Subscapular elastofibroma intermingled with adipose tissue: variant type of elastofibroma or lipoma?. Ann Diagn Pathol. 2005 Dec. 9(6):327-9. [Medline].

  26. Bianchi S, Martinoli C, Abdelwahab IF, Gandolfo N, Derchi LE, Damiani S. Elastofibroma dorsi: sonographic findings. AJR Am J Roentgenol. 1997 Oct. 169(4):1113-5. [Medline].

  27. Solivetti FM, Bacaro D, Di Luca Sidozzi A, Cecconi P. Elastofibroma dorsi: ultrasound pattern in three patients. J Exp Clin Cancer Res. 2003 Dec. 22(4):565-9. [Medline].

  28. Hartavi A, Duman A, Yetisgin A, Ekiz T. Elastofibroma Dorsi: Multimodal Imaging. PM R. 2014 May 16. [Medline].

  29. Naylor MF, Nascimento AG, Sherrick AD, McLeod RA. Elastofibroma dorsi: radiologic findings in 12 patients. AJR Am J Roentgenol. 1996 Sep. 167(3):683-7. [Medline].

  30. Valls R, Melloni P, Darnell A, Sanchez-Flo R. Elastofibroma dorsi: a chest wall pseudotumor. Computed tomography and magnetic resonance imaging diagnosis. Acta Orthop Belg. 1996 Jun. 62(2):103-6. [Medline].

  31. Kudo S. Elastofibroma dorsi: CT and MR imaging findings. Semin Musculoskelet Radiol. 2001 Jun. 5(2):103-5. [Medline].

  32. Oueslati S, Douira-Khomsi W, Bouaziz MC, Zaouia K. Elastofibroma dorsi: A report on 6 cases. Acta Orthop Belg. 2006 Apr. 72(2):237-42. [Medline].

  33. Alouini R, Allani M, Harzallah L, Bahri M, Kraiem C, Tlili-Graies K. [Elastofibroma: imaging features]. J Radiol. 2005 Nov. 86(11):1712-5. [Medline].

  34. Yanez S, Val-Bernal JF, Echevarria MA, Landeras R, Izquierdo J, Gallardo E. [Retrospective analysis of 6 cases of elastofibroma dorsi]. Actas Dermosifiliogr. 2008 Oct. 99(8):644-7. [Medline].

  35. Tamimi Mariño I, Sesma Solis P, Pérez Lara A, Martinez Malo J, Vazquez ML, Tamimi F. Sensitivity and positive predictive value of magnetic resonance imaging in the diagnosis of elastofibroma dorsi: review of fourteen cases. J Shoulder Elbow Surg. 2013 Jan. 22(1):57-63. [Medline].

  36. Minarro JC, Urbano-Luque MT, López-Jordan A, Roman-Torres M, Carpintero-Benítez P. The comparison of measurement accuracy among three different imaging modalities in evaluating elastofibroma dorsi. An analysis of 52 cases. Int Orthop. 2015 Jun. 39 (6):1145-9. [Medline].

  37. Wasyliw CW, Caride VJ. Incidental detection of bilateral elastofibroma dorsi with F-18 FDG PET/CT. Clin Nucl Med. 2005 Oct. 30(10):700-1. [Medline].

  38. Kai K, Kusano K, Sakai M, et al. Active neovascularization and possible vascular-centric development of gastric and periscapular elastofibromas. Virchows Arch. 2009 Feb. 454(2):181-8. [Medline].

  39. Kayaselcuk F, Demirhan B, Kayaselcuk U, Ozerdem OR, Tuncer I. Vimentin, smooth muscle actin, desmin, S-100 protein, p53, and estrogen receptor expression in elastofibroma and nodular fasciitis. Ann Diagn Pathol. 2002 Apr. 6(2):94-9. [Medline].

  40. Tasli F, Vardar E, Argon A, Kabat T, Deniz S, Nart A, et al. Histochemical and immunohistochemical characteristics of elastofibromas. Pol J Pathol. 2014. 65(2):120-4. [Medline].

  41. Mortman KD, Hochheiser GM, Giblin EM, Manon-Matos Y, Frankel KM. Elastofibroma dorsi: clinicopathologic review of 6 cases. Ann Thorac Surg. 2007 May. 83(5):1894-7. [Medline].

  42. Parratt MT, Donaldson JR, Flanagan AM, Saifuddin A, Pollock RC, Skinner JA, et al. Elastofibroma dorsi: management, outcome and review of the literature. J Bone Joint Surg Br. 2010 Feb. 92(2):262-6. [Medline].

  43. Koksel O, Demir Apaydin F, Ayan E, Demir M, Ozdulger A. Elastofibroma dorsi: Review of eight cases. Surg Today. 2010 May. 40(5):423-7. [Medline].

  44. Nagano S, Yokouchi M, Setoyama T, Sasaki H, Shimada H, Kawamura I, et al. Elastofibroma dorsi: Surgical indications and complications of a rare soft tissue tumor. Mol Clin Oncol. 2014 May. 2(3):421-424. [Medline]. [Full Text].

  45. Patnayak R, Jena A, Settipalli S, Nagesh N. Elastofibroma: An Uncommon Tumor Revisited. J Cutan Aesthet Surg. 2016 Jan-Mar. 9 (1):34-7. [Medline].

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