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Fibrous Papule of the Face Treatment & Management

  • Author: Simone Laube, MD, MRCP; Chief Editor: Dirk M Elston, MD  more...
 
Updated: Oct 09, 2015
 

Surgical Care

The lesion is benign, but it may be removed to confirm the diagnosis or for cosmetic reasons. Surgical procedures include curettage, shave excision, or elliptical excision. Laser treatment with pulsed dye laser, CO2 laser, and KTP laser has been successfully used for the treatment of angiofibromas such as tuberous sclerosis.

 

 
 
Contributor Information and Disclosures
Author

Simone Laube, MD, MRCP Consulting Staff, Department of Dermatology, Borders General Hospital, Melrose and Western General Hospital, Edinburgh

Simone Laube, MD, MRCP is a member of the following medical societies: British Association of Dermatologists, Scottish Dermatological Society

Disclosure: Serve(d) as a speaker or a member of a speakers bureau for: Galderma.

Specialty Editor Board

Michael J Wells, MD, FAAD Associate Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine

Michael J Wells, MD, FAAD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, Texas Medical Association

Disclosure: Nothing to disclose.

Jeffrey Meffert, MD Associate Clinical Professor of Dermatology, University of Texas School of Medicine at San Antonio

Jeffrey Meffert, MD is a member of the following medical societies: American Academy of Dermatology, American Medical Association, Association of Military Dermatologists, Texas Dermatological Society

Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Acknowledgements

The authors and editors of Medscape Reference gratefully acknowledge the contributions of previous coauthor Ravi Ratnavel, MD, to the development and writing of this article.

References
  1. Nemeth AJ, Penneys NS, Bernstein HB. Fibrous papule: a tumor of fibrohistiocytic cells that contain factor XIIIa. J Am Acad Dermatol. 1988 Dec. 19(6):1102-6. [Medline].

  2. Chan JY, Wang KH, Fang CL, Chen WY. Fibrous papule of the face, similar to tuberous sclerosis complex-associated angiofibroma, shows activation of the mammalian target of rapamycin pathway: evidence for a novel therapeutic strategy?. PLoS One. 2014. 9 (2):e89467. [Medline].

  3. Elifritz J, Krishnan RS, Donnelly H. Numerous fibrous papules of the face unassociated with any genodermatosis. Dermatol Online J. 2007 Oct 13. 13 (4):12. [Medline].

  4. Tope WD, Sangueza OP. Rhinophyma's fibrous variant. Histopathology and immunohistochemistry. Am J Dermatopathol. 1994 Jun. 16(3):307-10. [Medline].

  5. Odell EW, Lock C, Lombardi TL. Phenotypic characterisation of stellate and giant cells in giant cell fibroma by immunocytochemistry. J Oral Pathol Med. 1994 Jul. 23(6):284-7. [Medline].

  6. Kucher C, McNiff JM. Epithelioid fibrous papule - a new variant. J Cutan Pathol. 2007 Jul. 34(7):571-5. [Medline].

  7. Lee AN, Stein SL, Cohen LM. Clear cell fibrous papule with NKI/C3 expression: clinical and histologic features in six cases. Am J Dermatopathol. 2005 Aug. 27(4):296-300. [Medline].

  8. Park HS, Cho S, Kim KH, Won CH. Fibrous papule of the face, clear cell type: a case report. J Eur Acad Dermatol Venereol. 2007 Oct. 21(9):1267-8. [Medline].

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Fibrous papule of the nose. Courtesy of San Antonio Uniformed Services Health Education Consortium Dermatology slide files.
Histopathology of a fibrous papule shows focal fibrosis and vascular proliferation in the upper dermis. Courtesy of Dirk Elston, MD.
 
 
 
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