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Pilomatrixoma Treatment & Management

  • Author: Jaggi Rao, MD, FRCPC; Chief Editor: Dirk M Elston, MD  more...
Updated: Mar 20, 2015

Medical Care

Medical treatment is not successful.


Surgical Care

Spontaneous regression has never been observed. The treatment of choice is surgical excision.[83, 84] Lesions are mostly poorly delineated, but encapsulated forms have been observed; these are less likely to recur because complete resection is easier. Incomplete resections have been followed by local recurrence; wide resection margins (1-2 cm) have been recommended to minimize the risk of recurrence. Secondary lesions after surgery are rare; this risk decreases progressively with age. In addition, Mohs micrographic surgery has been used in an effort to ensure better margin control.

Contributor Information and Disclosures

Jaggi Rao, MD, FRCPC Clinical Professor of Medicine, Division of Dermatology and Cutaneous Sciences, Director of Dermatology Residency Program, University of Alberta Faculty of Medicine and Dentistry

Jaggi Rao, MD, FRCPC is a member of the following medical societies: American Academy of Dermatology, American Society for Dermatologic Surgery, American Society for Laser Medicine and Surgery, Canadian Medical Association, Pacific Dermatologic Association, Royal College of Physicians and Surgeons of Canada, Canadian Medical Protective Association, Canadian Dermatology Association

Disclosure: Nothing to disclose.


Andrew Lin, MD, FRCPC Associate Professor, Department of Internal Medicine, Division of Dermatology, University of Alberta

Andrew Lin, MD, FRCPC is a member of the following medical societies: American Academy of Dermatology, Royal College of Physicians and Surgeons of Canada

Disclosure: Nothing to disclose.

Specialty Editor Board

Richard P Vinson, MD Assistant Clinical Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine; Consulting Staff, Mountain View Dermatology, PA

Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Texas Medical Association, Association of Military Dermatologists, Texas Dermatological Society

Disclosure: Nothing to disclose.

Warren R Heymann, MD Head, Division of Dermatology, Professor, Department of Internal Medicine, Rutgers New Jersey Medical School

Warren R Heymann, MD is a member of the following medical societies: American Academy of Dermatology, American Society of Dermatopathology, Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.


Smeena Khan, MD Private Practice, Adult and Pediatric Dermatology Associates

Smeena Khan, MD is a member of the following medical societies: Alpha Omega Alpha and American Academy of Dermatology

Disclosure: Nothing to disclose.

Andrei I Metelitsa, MD Chief Resident, Division of Dermatology and Cutaneous Sciences, University of Alberta, Canada

Disclosure: Nothing to disclose.

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Pilomatricoma with prominent basaloid cells.
Ghost cells (shadow cells) and basaloid cells, associated with a granulomatous reaction. Shadow cells are also seen in this high-power micrograph.
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