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Warty Dyskeratoma Treatment & Management

  • Author: Molly Ann Allen Hinshaw, MD; Chief Editor: Dirk M Elston, MD  more...
 
Updated: Aug 17, 2015
 

Medical Care

No medical care is required.

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Surgical Care

Removal of the lesion by performing a punch biopsy or an excisional biopsy is an effective therapy for these benign lesions.

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Diet

This benign process is unrelated to dietary influences.

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Contributor Information and Disclosures
Author

Molly Ann Allen Hinshaw, MD Clinical Associate Professor, Department of Dermatology, University of Wisconsin School of Medicine and Public Health

Molly Ann Allen Hinshaw, MD is a member of the following medical societies: American Academy of Dermatology, American Society of Dermatopathology, Women's Dermatologic Society, Wisconsin Dermatological Society, International Society of Dermatopathology, Dermatology Foundation

Disclosure: Have a 5% or greater equity interest in: Accure Medical, I founded this company with two partners so have 33% interest in the company. We have spent our personal funds to start the company, have no products, and no income yet.

Specialty Editor Board

Richard P Vinson, MD Assistant Clinical Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine; Consulting Staff, Mountain View Dermatology, PA

Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Texas Medical Association, Association of Military Dermatologists, Texas Dermatological Society

Disclosure: Nothing to disclose.

Rosalie Elenitsas, MD Herman Beerman Professor of Dermatology, University of Pennsylvania School of Medicine; Director, Penn Cutaneous Pathology Services, Department of Dermatology, University of Pennsylvania Health System

Rosalie Elenitsas, MD is a member of the following medical societies: American Academy of Dermatology, American Medical Association, American Society of Dermatopathology, Pennsylvania Academy of Dermatology

Disclosure: Received royalty from Lippincott Williams Wilkins for textbook editor.

Chief Editor

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Additional Contributors

Timothy McCalmont, MD Director, UCSF Dermatopathology Service, Professor of Clinical Pathology and Dermatology, Departments of Pathology and Dermatology, University of California at San Francisco; Editor-in-Chief, Journal of Cutaneous Pathology

Timothy McCalmont, MD is a member of the following medical societies: Alpha Omega Alpha, American Medical Association, American Society of Dermatopathology, California Medical Association, College of American Pathologists, United States and Canadian Academy of Pathology

Disclosure: Received consulting fee from Apsara for independent contractor.

References
  1. Szymanski FJ. Warty dyskeratoma; a benign cutaneous tumor resembling Darier's disease microscopically. Arch Derm. 1957 Apr. 75(4):567-72. [Medline].

  2. Allon I, Buchner A. Warty dyskeratoma/focal acantholytic dyskeratosis--an update on a rare oral lesion. J Oral Pathol Med. Mar 2012. 41(3):261-7. [Medline].

  3. Azuma Y, Matsukawa A. Warty dyskeratoma with multiple lesions. J Dermatol. 1993 Jun. 20(6):374-7. [Medline].

  4. Duray PH, Merino MJ, Axiotis C. Warty dyskeratoma of the vulva. Int J Gynecol Pathol. 1983. 2(3):286-93. [Medline].

  5. Koç M, Kavala M, Kocatürk E, Mete O, Can B, Zindanci I, et al. Multiple warty dyskeratomas on the scalp. Dermatol Online J. 2009 Feb. 15(2):8. [Medline].

  6. Heymann WR. Warty dyskeratoma appearing in a patient with Darier's disease. Int J Dermatol. 1988 Sep. 27(7):521-2. [Medline].

  7. Allon I, Buchner A. Warty dyskeratoma/focal acantholytic dyskeratosis - an update on a rare oral lesion. J Oral Pathol Med. 2011 Sep 21. [Medline].

  8. Jang EJ, Lee JY, Kim MK, Yoon TY. Warty dyskeratoma involving two adjoining follicles. Ann Dermatol. 2011 Feb. 23(1):98-100. [Medline]. [Full Text].

  9. Savignac M, Edir A, Simon M, Hovnanian A. Darier disease : a disease model of impaired calcium homeostasis in the skin. Biochim Biophys Acta. 2011 May. 1813(5):1111-7. [Medline].

  10. Kaddu S, Dong H, Mayer G, Kerl H, Cerroni L. Warty dyskeratoma--"follicular dyskeratoma": analysis of clinicopathologic features of a distinctive follicular adnexal neoplasm. J Am Acad Dermatol. 2002 Sep. 47(3):423-8. [Medline].

  11. Baran R, Perrin C. Focal subungual warty dyskeratoma. Dermatology. 1997. 195(3):278-80. [Medline].

  12. Cohen PR. Longitudinal erythronychia: individual or multiple linear red bands of the nail plate: a review of clinical features and associated conditions. Am J Clin Dermatol. 2011 Aug 1. 12 (4):217-31. [Medline].

  13. Szymanski FJ. Warty dyskeratoma; a benign cutaneous tumor resembling Darier's disease microscopically. AMA Arch Derm. 1957 Apr. 75(4):567-72. [Medline].

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Absence of sarco/endoplasmic reticulum Ca2+ ATPase 2 (SERCA2) staining by immunohistochemistry within a warty dyskeratoma (right side of image), in contrast to the unaffected epidermis (left side of image). Photomicrograph courtesy of James E. Fitzpatrick, MD.
Warty dyskeratoma. An endo-exophytic squamous proliferation of cytologically benign, acantholytic, and dyskeratotic keratinocytes.
Villi lined by acantholytic keratinocytes, some of which are dyskeratotic (corps ronds and corps grains).
 
 
 
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