Trichofolliculoma Follow-up

  • Author: Michael S Howard, MD; Chief Editor: Dirk M Elston, MD   more...
 
Updated: Jan 13, 2012
 

Prognosis

The prognosis is excellent. Although reports exist of recurrence at the primary site, these events are rare.

 
Contributor Information and Disclosures
Author

Michael S Howard, MD  Dermatopathologist and Laboratory Director, Georgia Dermatopathology Associates

Disclosure: Nothing to disclose.

Coauthor(s)

Bruce R Smoller, MD  Executive Vice President, United States and Canadian Academy of Pathology

Bruce R Smoller, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, American Society of Dermatopathology, and Arkansas Medical Society

Disclosure: Nothing to disclose.

Specialty Editor Board

James W Patterson, MD  Professor of Pathology and Dermatology, Director of Dermatopathology, University of Virginia Medical Center

James W Patterson, MD is a member of the following medical societies: American Academy of Dermatology, American College of Physicians, American Society of Dermatopathology, Royal Society of Medicine, Society for Investigative Dermatology, and United States and Canadian Academy of Pathology

Disclosure: Nothing to disclose.

Richard P Vinson, MD  Assistant Clinical Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine; Consulting Staff, Mountain View Dermatology, PA

Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Association of Military Dermatologists, Texas Dermatological Society, and Texas Medical Association

Disclosure: Nothing to disclose.

Rosalie Elenitsas, MD  Herman Beerman Associate Professor of Dermatology, University of Pennsylvania School of Medicine; Director, Penn Cutaneous Pathology Services, Department of Dermatology, University of Pennsylvania Health System

Rosalie Elenitsas, MD is a member of the following medical societies: American Academy of Dermatology and American Society of Dermatopathology

Disclosure: Lippincott Williams Wilkins Royalty Textbook editor; DLA Piper Consulting fee Consulting

Joel M Gelfand, MD, MSCE  Medical Director, Clinical Studies Unit, Assistant Professor, Department of Dermatology, Associate Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania

Joel M Gelfand, MD, MSCE is a member of the following medical societies: Society for Investigative Dermatology

Disclosure: AMGEN Consulting fee Consulting; AMGEN Grant/research funds Investigator; Genentech Grant/research funds investigator; Centocor Consulting fee Consulting; Abbott Grant/research funds investigator; Abbott Consulting fee Consulting; Novartis investigator; Pfizer Grant/research funds investigator; Celgene Consulting fee DMC Chair; NIAMS and NHLBI Grant/research funds investigator

Chief Editor

Dirk M Elston, MD  Director, Ackerman Academy of Dermatopathology, New York

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

References

  1. Ishii N, Kawaguchi H, Takahashi K, Nakajima H. A case of congenital trichofolliculoma. J Dermatol. Mar 1992;19(3):195-6. [Medline].

  2. Cole P, Kaufman Y, Dishop M, Hatef DA, Hollier L. Giant, congenital folliculosebaceous cystic hamartoma: a case against a pathogenetic relationship with trichofolliculoma. Am J Dermatopathol. Oct 2008;30(5):500-3. [Medline].

  3. Wu YH. Folliculosebaceous cystic hamartoma or trichofolliculoma? A spectrum of hamartomatous changes inducted by perifollicular stroma in the follicular epithelium. J Cutan Pathol. Sep 2008;35(9):843-8. [Medline].

  4. Misago N, Kimura T, Toda S, Mori T, Narisawa Y. A revaluation of trichofolliculoma: the histopathological and immunohistochemical features. Am J Dermatopathol. Feb 2010;32(1):35-43. [Medline].

  5. Hartschuh W, Schulz T. Immunohistochemical investigation of the different developmental stages of trichofolliculoma with special reference to the Merkel cell. Am J Dermatopathol. Feb 1999;21(1):8-15. [Medline].

  6. Plewig G. Sebaceous trichofolliculoma. J Cutan Pathol. Dec 1980;7(6):394-403. [Medline].

  7. Tanimura S, Arita K, Iwao F, et al. Two cases of folliculosebaceous cystic hamartoma. Clin Exp Dermatol. Jan 2006;31(1):68-70. [Medline].

  8. Stern JB, Stout DA. Trichofolliculoma showing perineural invasion. Trichofolliculocarcinoma?. Arch Dermatol. Aug 1979;115(8):1003-4. [Medline].

  9. Gray HR, Helwig EB. Trichofolliculoma. Arch Dermatol. 1962;86:99-105.

  10. Headington JT. Tumors of hair follicle differentiation. In: Farmer E, Hood A, eds. Pathology of the Skin. New York, NY: McGraw-Hill; 1990:596-614.

  11. Kligman AM, Pinkus H. The histogenesis of nevoid tumors of the skin. The folliculoma--a hair-follicle tumor. Arch Dermatol. Jun 1960;81:922-30. [Medline].

  12. McKee P. Farmer E, Hood A, eds. Pathology of the Skin. 2nd ed. New York, NY: McGraw-Hill; 1996:15.25-15.28.

  13. Pinkus H, Sutton RL Jr. Trichofolliculoma. Arch Dermatol. Jan 1965;91:46-9. [Medline].

  14. Wick MR, Swanson PE, Barnhill RL. Sebaceous and pilar tumors. In: Barnhill R, ed. Textbook of Dermatopathology. New York, NY: McGraw-Hill; 1998:593-621.

 
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Low-power view of trichofolliculoma with a primary follicle opening onto the skin surface.
Edge of the primary follicle with associated secondary and tertiary budding follicular structures.
Higher magnification of budding follicular structures.
Low-power view of a section of trichofolliculoma demonstrating budding follicular structures and associated stroma.
Higher magnification of budding follicular structures and associated stroma.
Low-power view of sebaceous trichofolliculoma demonstrating dilated, primary follicle; budding follicular structures; and numerous associated sebaceous lobules.
Higher magnification of central primary follicle and associated sebaceous lobules.
Clinical appearance of trichofolliculoma.
 
 
 
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