Familial Benign Pemphigus (Hailey-Hailey Disease): Multimedia

References

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2. Fairclough RJ, Dode L, Vanoevelen J, Andersen JP, Missiaen L, Raeymaekers L, et al. Effect of Hailey-Hailey Disease mutations on the function of a new variant of human secretory pathway Ca2+/Mn2+-ATPase (hSPCA1). J Biol Chem. Jul 4 2003;278(27):24721-30. [Medline].

3. Foggia L, Aronchik I, Aberg K, Brown B, Hovnanian A, Mauro TM. Activity of the hSPCA1 Golgi Ca2+ pump is essential for Ca2+-mediated Ca2+ response and cell viability in Darier disease. J Cell Sci. Feb 15 2006;119(Pt 4):671-9. [Medline].

4. Zhu YG, Yang S, Gao M, Chen JJ, Li W, Wang PG, et al. Two novel mutations of the ATP2C1 gene in Chinese families with Hailey-Hailey disease. J Dermatol Sci. May 2006;42(2):125-7. [Medline].

5. Hunt MJ, Salisbury EL, Painter DM, Lee S. Vesiculobullous Hailey-Hailey disease: successful treatment with oral retinoids. Australas J Dermatol. Nov 1996;37(4):196-8. [Medline].

6. Rabeni EJ, Cunningham NM. Effective treatment of Hailey-Hailey disease with topical tacrolimus. J Am Acad Dermatol. Nov 2002;47(5):797-8. [Medline].

7. Ruiz-Rodriguez R, Alvarez JG, Jaén P, Acevedo A, Córdoba S. Photodynamic therapy with 5-aminolevulinic acid for recalcitrant familial benign pemphigus (Hailey-Hailey disease). J Am Acad Dermatol. Nov 2002;47(5):740-2. [Medline].

8. Konrad H, Karamfilov T, Wollina U. Intracutaneous botulinum toxin A versus ablative therapy of Hailey-Hailey disease--a case report. J Cosmet Laser Ther. Dec 2001;3(4):181-4. [Medline].

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10. Berger EM, Galadari HI, Hassan I, Gottleib AB. Successful treatment of Hailey-Hailey disease with acitretin. Journal of Drugs in Dermatology. July 2007;6:734-6. [Medline].

11. Hurd DS, Johnston C, Bevins A. A case report of Hailey-Hailey disease treated with alefacept (Amevive). Br J Dermatol. Feb 2008;158(2):399-401. [Medline].

12. Don PC, Carney PS, Lynch WS, Zaim MT, Hassan MO. Carbon dioxide laserabrasion: a new approach to management of familial benign chronic pemphigus (Hailey-Hailey disease). J Dermatol Surg Oncol. Nov 1987;13(11):1187-94. [Medline].

13. Fisher GH, Geronemus RG. Improvement of familial benign pemphigus after treatment with pulsed-dye laser: a case report. Dermatol Surg. Jul 2006;32(7):966-8. [Medline].

14. Kartamaa M, Reitamo S. Familial benign chronic pemphigus (Hailey-Hailey disease). Treatment with carbon dioxide laser vaporization. Arch Dermatol. May 1992;128(5):646-8. [Medline].

15. Berth-Jones J, Smith SG, Graham-Brown RA. Benign familial chronic pemphigus (Hailey-Hailey disease) responds to cyclosporin. Clin Exp Dermatol. Jan 1995;20(1):70-2. [Medline].

16. Burge SM. Hailey-Hailey disease: the clinical features, response to treatment and prognosis. Br J Dermatol. Mar 1992;126(3):275-82. [Medline].

17. Cooley JE, Briggaman RA, Cronce DJ, Banes AJ, O'Keefe EJ. Hailey-Hailey disease keratinocytes: normal assembly of cell-cell junctions in vitro. J Invest Dermatol. Dec 1996;107(6):877-81. [Medline].

18. Dadban A, Guillot B. Oesophageal involvement in familial benign chronic pemphigus. Acta Derm Venereol. 2006;86(3):252-3. [Medline].

19. De Dobbeleer G, De Graef C, M'Poudi E, Gourdain JM, Heenen M. Reproduction of the characteristic morphologic changes of familial benign chronic pemphigus in cultures of lesional keratinocytes onto dead deepidermized dermis. J Am Acad Dermatol. Nov 1989;21(5 Pt 1):961-5. [Medline].

20. Fisher BK, Margesson LJ. Hailey-Hailey disease (familial benign chronic pemphigus). In: Genital Skin Disorders: Diagnosis and Treatment. St. Louis, Mo: Mosby-Year Book; 1998:68, 117.

21. Flint ID, Spencer DM, Wilkin JK. Eczema herpeticum in association with familial benign chronic pemphigus. J Am Acad Dermatol. Feb 1993;28(2 Pt 1):257-9. [Medline].

22. Galimberti RL, Kowalczuk AM, Bianchi O, Bonino MV, Garcia Garcia A. Chronic benign familial pemphigus. Int J Dermatol. Sep 1988;27(7):495-500. [Medline].

23. Gokdemir G, Gonen S, Kivanç-Altunay I, Köslü A. Familial pemphigus vulgaris: two siblings with unusual localized variant. Int J Dermatol. Feb 2006;45(2):170-2. [Medline].

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25. Ikeda S, Suga Y, Ogawa H. Successful management of Hailey-Hailey disease with potent topical steroid ointment. J Dermatol Sci. Jun 1993;5(3):205-11. [Medline].

26. Ishibashi Y, Kajiwara Y, Andoh I, Inoue Y, Kukita A. The nature and pathogenesis of dyskeratosis in Hailey-Hailey's disease and Darier's disease. J Dermatol. Aug 1984;11(4):335-53. [Medline].

27. Metze D, Hamm H, Schorat A, Luger T. Involvement of the adherens junction-actin filament system in acantholytic dyskeratosis of Hailey-Hailey disease. A histological, ultrastructural, and histochemical study of lesional and non-lesional skin. J Cutan Pathol. Jun 1996;23(3):211-22. [Medline].

28. Oguz O, Gökler G, Ocakoglu O, Oguz V, Demirkesen C, Aydemir EH. Conjunctival involvement in familial chronic benign pemphigus (Hailey-Hailey disease). Int J Dermatol. Apr 1997;36(4):282-5. [Medline].

29. Remitz A, Lauerma AI, Stubb S, Förström L, Reitamo S. Darier's disease, familial benign chronic pemphigus (Hailey-Hailey disease) and contact hypersensitivity. J Am Acad Dermatol. Jan 1990;22(1):134. [Medline].

30. Sehgal VN, Jain S. Chronic familial benign pemphigus. J Dermatol. Jun 1994;21(6):382-8. [Medline].

31. Starzycki Z, Chorzelski TP, Jablonska S. Familial pemphigus vulgaris in mother and daughter. Int J Dermatol. Mar 1998;37(3):211-4. [Medline].

32. Welsh EA, Ikeda S, Peluso AM, Bonifas JM, Bare JW, Woodley DT, et al. Hailey-Hailey disease is not allelic to Darier's disease. J Invest Dermatol. Jun 1994;102(6):992-3. [Medline].

Further Reading

Keywords

pemphigus, benign familial pemphigus, familial benign pemphigus, bullous disease, Hailey-Hailey disease

Contributor Information and Disclosures

Author

Thomas N Helm, MD, Clinical Associate Professor, Departments of Dermatology and Pathology, State University of New York at Buffalo; Director, Buffalo Medical Group Dermatopathology Laboratory
Thomas N Helm, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Society for Dermatologic Surgery, and American Society of Dermatopathology
Disclosure: Nothing to disclose.

Coauthor(s)

Thomas C Lee, MD, Intern, Department of Internal Medicine, New York University School of Medicine
Disclosure: Nothing to disclose.

Medical Editor

David Woodley, MD, Co-Chair, Professor, Department of Medicine, Division of Dermatology, University of Southern California
David Woodley, MD, Co-Chair is a member of the following medical societies: American Academy of Dermatology, American Association for the Advancement of Science, American College of Emergency Physicians, American College of Physicians, American Federation for Medical Research, American Society for Clinical Investigation, New York Academy of Medicine, Society for Investigative Dermatology, and Southern Medical Association
Disclosure: Nothing to disclose.

Pharmacy Editor

Michael J Wells, MD, Associate Professor, Department of Dermatology, Texas Tech University Health Sciences Center
Michael J Wells, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, and Texas Medical Association
Disclosure: Nothing to disclose.

Managing Editor

Julia R Nunley, MD, Professor, Program Director, Dermatology Residency, Department of Dermatology, Virginia Commonwealth University Medical Center
Julia R Nunley, MD is a member of the following medical societies: American Academy of Dermatology, American College of Physicians, American Society of Nephrology, International Society of Nephrology, Medical Dermatology Society, Medical Society of Virginia, National Kidney Foundation, Phi Beta Kappa, and Women's Dermatologic Society
Disclosure: Johnson and Johnson stock holder dividends; Amgen stock holder dividends; Forest Lab, Inc stock holder dividends; Galaxo Smith Klein stock holder dividends; Covidien stock holder dividends; Novartis Grant/research funds Consulting; Biolex  sub-investigator

CME Editor

Catherine Quirk, MD, Clinical Assistant Professor, Department of Dermatology, Brown University
Catherine Quirk, MD is a member of the following medical societies: Alpha Omega Alpha and American Academy of Dermatology
Disclosure: Nothing to disclose.

Chief Editor

William D James, MD, Paul R Gross Professor of Dermatology, University of Pennsylvania School of Medicine; Vice-Chair, Program Director, Department of Dermatology, University of Pennsylvania Health System
William D James, MD is a member of the following medical societies: American Academy of Dermatology and Society for Investigative Dermatology
Disclosure: elsevier Royalty Other; american college of physicians Honoraria Other