eMedicine Specialties > Dermatology > Connective Tissue Diseases
Lupus Erythematosus, Drug-Induced: Follow-up
Updated: Aug 7, 2009
Follow-up
Further Outpatient Care
- In patients with drug-induced lupus erythematosus (DILE), monitor antinuclear antibody levels, anti-ssDNA, anti-dsDNA, antihistone antibody levels, serum complement levels, and urinalysis findings.
- Continue to monitor cardiac, renal, and pulmonary function if any of these were initially involved.
Complications
- In rare instances, patients may die of renal involvement.
Prognosis
- Prognosis is excellent once the causative medication is discontinued. Recovery generally occurs within days or weeks.
Patient Education
- For excellent patient education resources, visit eMedicine's Blood and Lymphatic System Center and Arthritis Center. Also, see eMedicine's patient education articles Lupus (Systemic Lupus Erythematosus) and Drug Allergy.
Miscellaneous
Medicolegal Pitfalls
- Failure to diagnose renal involvement: Death from drug-induced lupus erythematosus (DILE) is extremely rare but may result from renal involvement (eg, membranous proliferative and necrotizing glomerulonephritis)
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Follow-up: Lupus Erythematosus, Drug-Induced |
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References
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Further Reading
Keywords
drug-related lupus, lupuslike syndrome, lupus-like syndrome, lupus erythematosus medicamentosus, drug-induced systemic lupus erythematosus, SLE, drug-induced SLE, drug-induced systemic lupus erythematosus, renal idiopathic lupus, DILE, LE, drug-induced LE, autoimmune disease, procainamide, chlorpromazine, quinidine, acebutolol, amiodarone, bupropion, captopril, carbamazepine, chlorpromazine, diltiazem, docetaxel, ethosuximide, gemfibrozil, glyburide, gold salt, griseofulvin, hydantoins, hydralazine, hydroxychloroquine, interferons
interleukins, isoniazid, leuprolide acetate, lithium, lovastatin, mephenytoin, methyldopa, minocycline, nitrofurantoin, olanzapine, ophthalmic timolol, oral contraceptives, penicillamine, phenytoin, practolol, procainamide, propylthiouracil, quinidine, reserpine, rifampin, simvastatin, sulfasalazine, tetracycline, ticlopidine, tiotropium bromide inhaler, trimethadione, tumor necrosis factor, valproate, voriconazole, cimedtidine, hydralazine, hydrochlorothiazide, mesantoin, PABA, penicillin, phenylbutazone, sulfonamides, terbinafine, arthralgia, treatment, diagnosis
Follow-up: Lupus Erythematosus, Drug-Induced