eMedicine Specialties > Dermatology > Diseases of Pigmentation
Hypomelanosis of Ito: Follow-up
Updated: Aug 31, 2009
Follow-up
Further Inpatient Care
- No further inpatient care is needed for hypomelanosis of Ito (HI), except that indicated for the associated abnormalities.
Further Outpatient Care
- Routine outpatient care is sufficient, except when associated abnormalities require additional care.
Deterrence/Prevention
- Genetics counseling may aid in the prevention of hypomelanosis of Ito.
Complications
- Complications may occur as a result of associated abnormalities.
Prognosis
- The prognosis is determined by the associated abnormalities.
- The prognosis is excellent for the cutaneous findings.
Patient Education
- Genetic counseling may be recommended.
- However, the risk of hypomelanosis of Ito transmission is considered low, except when X-linked mutations are present in female patients.
Miscellaneous
Medicolegal Pitfalls
- Patients should undergo a thorough examination to identify any associated abnormalities and possible treatments.
- Although the risk of having more affected children is low, genetic counseling may be useful.
More on Hypomelanosis of Ito |
| Overview: Hypomelanosis of Ito |
| Differential Diagnoses & Workup: Hypomelanosis of Ito |
| Treatment & Medication: Hypomelanosis of Ito |
Follow-up: Hypomelanosis of Ito |
| Multimedia: Hypomelanosis of Ito |
| References |
| « Previous Page | Next Page » |
References
Nehal KS, PeBenito R, Orlow SJ. Analysis of 54 cases of hypopigmentation and hyperpigmentation along the lines of Blaschko. Arch Dermatol. Oct 1996;132(10):1167-70. [Medline].
Gupta S, Shah S, Mcgaw A, Mercado T, Zaslav AL, Tegay D. Trisomy 2 mosaicism in hypomelanosis of Ito. Am J Med Genet A. Oct 15 2007;143A(20):2466-8. [Medline].
McKusic VA. Online Mendelian Inheritance in Man (OMIM) [serial online]. 2000;Available at: http://w3.ncbi.nlm.nih.gov/Omim/. [Full Text].
Scott A, Micallef C, Hale SL, Watts P. Cortical visual impairment in hypomelanosis of Ito. J Pediatr Ophthalmol Strabismus. Jul-Aug 2008;45(4):240-1. [Medline].
Iype M, Iype T, Geetha S, Retnakumar J. Hypomelanosis of Ito with cerebral malformation. Indian J Pediatr. Nov 2007;74(11):1044-5. [Medline].
Vergine G, Mencarelli F, Diomedi-Camassei F, et al. Glomerulocystic kidney disease in hypomelanosis of Ito. Pediatr Nephrol. Jul 2008;23(7):1183-7. [Medline].
Donnai D, Read AP, McKeown C, Andrews T. Hypomelanosis of Ito: a manifestation of mosaicism or chimerism. J Med Genet. Dec 1988;25(12):809-18. [Medline].
Fritz B, Kuster W, Orstavik KH, Naumova A, Spranger J, Rehder H. Pigmentary mosaicism in hypomelanosis of Ito. Further evidence for functional disomy of Xp. Hum Genet. Oct 1998;103(4):441-9. [Medline].
Glover MT, Brett EM, Atherton DJ. Hypomelanosis of Ito: spectrum of the disease. J Pediatr. Jul 1989;115(1):75-80. [Medline].
Hatchwell E. Hypomelanosis of Ito and X;autosome translocations: a unifying hypothesis. J Med Genet. Mar 1996;33(3):177-83. [Medline].
Pascual-Castroviejo I, Roche C, Martinez-Bermejo A, et al. Hypomelanosis of ITO. A study of 76 infantile cases. Brain Dev. Jan 1998;20(1):36-43. [Medline].
Further Reading
Keywords
hypomelanosis of Ito, HI, incontinentia pigmenti achromians, hypopigmented whorls of skin along Blaschko lines
Follow-up: Hypomelanosis of Ito