Bromhidrosis Differential Diagnoses

  • Author: Wingfield Rehmus, MD, MPH; Chief Editor: William D James, MD   more...
 
Updated: Jan 17, 2012
 
 

Differential Diagnoses

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Contributor Information and Disclosures
Author

Wingfield Rehmus, MD, MPH  Dermatologist, BC Children's Hospital, Vancouver, British Columbia

Wingfield Rehmus, MD, MPH is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Coauthor(s)

Carol E Cheng  Boston University School of Medicine

Disclosure: Nothing to disclose.

Katherine Brown  Stanford University School of Medicine

Katherine Brown, is a member of the following medical societies: American Medical Student Association/Foundation

Disclosure: Nothing to disclose.

Specialty Editor Board

Timothy McCalmont, MD  Director, UCSF Dermatopathology Service, Professor of Clinical Pathology and Dermatology, Departments of Pathology and Dermatology, University of California at San Francisco; Editor-in-Chief, Journal of Cutaneous Pathology

Timothy McCalmont, MD is a member of the following medical societies: Alpha Omega Alpha, American Medical Association, American Society of Dermatopathology, California Medical Association, College of American Pathologists, and United States and Canadian Academy of Pathology

Disclosure: Apsara Consulting fee Independent contractor

David F Butler, MD  Professor of Dermatology, Texas A&M University College of Medicine; Chair, Department of Dermatology, Director, Dermatology Residency Training Program, Scott and White Clinic, Northside Clinic

David F Butler, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, American Society for Dermatologic Surgery, American Society for MOHS Surgery, Association of Military Dermatologists, and Phi Beta Kappa

Disclosure: Nothing to disclose.

Jeffrey J Miller, MD  Associate Professor of Dermatology, Pennsylvania State University College of Medicine; Staff Dermatologist, Pennsylvania State Milton S Hershey Medical Center

Jeffrey J Miller, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, Association of Professors of Dermatology, North American Hair Research Society, and Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Glen H Crawford, MD  Assistant Clinical Professor, Department of Dermatology, University of Pennsylvania School of Medicine; Chief, Division of Dermatology, The Pennsylvania Hospital

Glen H Crawford, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, Phi Beta Kappa, and Society of USAF Flight Surgeons

Disclosure: Nothing to disclose.

Chief Editor

William D James, MD  Paul R Gross Professor of Dermatology, Vice-Chairman, Residency Program Director, Department of Dermatology, University of Pennsylvania School of Medicine

William D James, MD is a member of the following medical societies: American Academy of Dermatology and Society for Investigative Dermatology

Disclosure: Elsevier Royalty Other

Additional Contributors

The authors and editors of eMedicine gratefully acknowledge the contributions of previous authors, Shereen Timani, MD, and Nelly Rubeiz, MD, to the development and writing of this article.

References

  1. He J, Wang T, Dong J. A close positive correlation between malodor and sweating as a marker for the treatment of axillary bromhidrosis with botulinum toxin A. J Dermatolog Treat. Jul 31 2011;[Medline].

  2. Guillet G, Zampetti A, Aballain-Colloc ML. Correlation between bacterial population and axillary and plantar bromidrosis: study of 30 patients. Eur J Dermatol. Jan-Feb 2000;10(1):41-2. [Medline].

  3. Leyden JJ, McGinley KJ, Holzle E, Labows JN, Kligman AM. The microbiology of the human axilla and its relationship to axillary odor. J Invest Dermatol. Nov 1981;77(5):413-6. [Medline].

  4. Lindsay SL, Holmes S, Corbett AD, Harker M, Bovell DL. Innervation and receptor profiles of the human apocrine (epitrichial) sweat gland: routes for intervention in bromhidrosis. Br J Dermatol. Sep 2008;159(3):653-60. [Medline].

  5. Natsch A, Derrer S, Flachsmann F, Schmid J. A broad diversity of volatile carboxylic acids, released by a bacterial aminoacylase from axilla secretions, as candidate molecules for the determination of human-body odor type. Chem Biodivers. Jan 2006;3(1):1-20. [Medline].

  6. Spielman AI, Sunavala G, Harmony JA, et al. Identification and immunohistochemical localization of protein precursors to human axillary odors in apocrine glands and secretions. Arch Dermatol. Jul 1998;134(7):813-8. [Medline].

  7. Zeng C, Spielman AI, Vowels BR, Leyden JJ, Biemann K, Preti G. A human axillary odorant is carried by apolipoprotein D. Proc Natl Acad Sci U S A. Jun 25 1996;93(13):6626-30. [Medline].

  8. Sato T, Sonoda T, Itami S, Takayasu S. Predominance of type I 5alpha-reductase in apocrine sweat glands of patients with excessive or abnormal odour derived from apocrine sweat (osmidrosis). Br J Dermatol. Nov 1998;139(5):806-10. [Medline].

  9. Mao GY, Yang SL, Zheng JH. Cause of axillary bromidrosis. Plast Reconstr Surg. Feb 2009;123(2):81e-82e. [Medline].

  10. Mao GY, Yang SL, Zheng JH. Etiology and management of axillary bromidrosis: a brief review. Int J Dermatol. Oct 2008;47(10):1063-8. [Medline].

  11. Eun HC, Kim KH, Lee YS. Unusual body odour due to a nasal foreign body in a child. J Dermatol. Oct 1984;11(5):501-3. [Medline].

  12. Golding IM. An unusual cause of bromidrosis. Pediatrics. Nov 1965;36(5):791-2. [Medline].

  13. Katz HP, Katz JR, Bernstein M, Marcin J. Unusual presentation of nasal foreign bodies in children. JAMA. Apr 6 1979;241(14):1496. [Medline].

  14. Lucky AW. Acquired bromhidrosis in an 8-year-old boy secondary to a nasal foreign body. Arch Dermatol. Jan 1991;127(1):129. [Medline].

  15. Moriarty RA. Nasal foreign body presenting as an unusual odor. Am J Dis Child. Jan 1978;132(1):97-8. [Medline].

  16. Bang YH, Kim JH, Paik SW, Park SH, Jackson IT, Lebeda R. Histopathology of apocrine bromhidrosis. Plast Reconstr Surg. Aug 1996;98(2):288-92. [Medline].

  17. Kunachak S, Wongwaisayawan S, Leelaudomlipi P. Noninvasive treatment of bromidrosis by frequency-doubled Q-switched Nd:YAG laser. Aesthetic Plast Surg. May-Jun 2000;24(3):198-201. [Medline].

  18. Heckmann M, Teichmann B, Pause BM, Plewig G. Amelioration of body odor after intracutaneous axillary injection of botulinum toxin A. Arch Dermatol. Jan 2003;139(1):57-9. [Medline].

  19. Heckmann M, Kutt S, Dittmar S, Hamm H. Making scents: improvement of olfactory profile after botulinum toxin-A treatment in healthy individuals. Dermatol Surg. Jan 2007;33(1 Spec No.):S81-7. [Medline].

  20. Lee JB, Kim BS, Kim MB, Oh CK, Jang HS, Kwon KS. A case of foul genital odor treated with botulinum toxin A. Dermatol Surg. Sep 2004;30(9):1233-5. [Medline].

  21. He J, Wang T, Dong J. Excision of apocrine glands and axillary superficial fascia as a single entity for the treatment of axillary bromhidrosis. J Eur Acad Dermatol Venereol. Jun 21 2011;[Medline].

  22. Battal NM, Hata Y. A classic surgical method for the treatment of axillary osmidrosis. Plast Reconstr Surg. Aug 1997;100(2):550-1. [Medline].

  23. Born G. Surgical treatment of axillary osmidrosis. Plast Reconstr Surg. Dec 1995;96(7):1753. [Medline].

  24. Fan YM, Wu ZH, Li SF, Chen QX. Axillary osmidrosis treated by partial removal of the skin and subcutaneous tissue en bloc and apocrine gland subcision. Int J Dermatol. Nov 2001;40(11):714-6. [Medline].

  25. Grazer FM. A noninvasive surgical treatment of axillary hyperhidrosis. Clin Dermatol. Jul-Sep 1992;10(3):357-64. [Medline].

  26. Park DH, Kim TM, Han DG, Ahn KY. A comparative study of the surgical treatment of axillary osmidrosis by instrument, manual, and combined subcutaneous shaving procedures. Ann Plast Surg. Nov 1998;41(5):488-97. [Medline].

  27. Wang HJ, Cheng TY, Chen TM. Surgical management of axillary bromidrosis--a modified skoog procedure by an axillary bipedicle flap approach. Plast Reconstr Surg. Sep 1996;98(3):524-9. [Medline].

  28. Wu WH, Ma S, Lin JT, Tang YW, Fang RH, Yeh FL. Surgical treatment of axillary osmidrosis: an analysis of 343 cases. Plast Reconstr Surg. Aug 1994;94(2):288-94. [Medline].

  29. Inaba M, Anthony J, Ezaki T, Mackinstry C. Regeneration of axillary hair and related phenomena after removal of deep dermal and subcutaneous tissue by a special "shaving" technique. J Dermatol Surg Oncol. Dec 1978;4(12):921-5. [Medline].

  30. Kim IH, Seo SL, Oh CH. Minimally invasive surgery for axillary osmidrosis: combined operation with CO2 laser and subcutaneous tissue remover. Dermatol Surg. Nov 1999;25(11):875-9. [Medline].

  31. Lillis PJ, Coleman WP 3rd. Liposuction for treatment of axillary hyperhidrosis. Dermatol Clin. Jul 1990;8(3):479-82. [Medline].

  32. Ou LF, Yan RS, Chen IC, Tang YW. Treatment of axillary bromhidrosis with superficial liposuction. Plast Reconstr Surg. Oct 1998;102(5):1479-85. [Medline].

  33. Tung TC. Endoscopic shaver with liposuction for treatment of axillary osmidrosis. Ann Plast Surg. Apr 2001;46(4):400-4. [Medline].

  34. Seo SH, Jang BS, Oh CK, Kwon KS, Kim MB. Tumescent superficial liposuction with curettage for treatment of axillary bromhidrosis. J Eur Acad Dermatol Venereol. Jan 2008;22(1):30-5. [Medline].

  35. Chung S, Yoo WM, Park YG, Shin KS, Park BY. Ultrasonic surgical aspiration with endoscopic confirmation for osmidrosis. Br J Plast Surg. Apr 2000;53(3):212-4. [Medline].

  36. Hong JP, Shin HW, Yoo SC, et al. Ultrasound-assisted lipoplasty treatment for axillary bromidrosis: clinical experience of 375 cases. Plast Reconstr Surg. Apr 1 2004;113(4):1264-9. [Medline].

  37. Park S. Very superficial ultrasound-assisted lipoplasty for the treatment of axillary osmidrosis. Aesthetic Plast Surg. Jul-Aug 2000;24(4):275-9. [Medline].

  38. Kao TH, Pan HC, Sun MH, Chang CS, Yang DY, Wang YC. Upper thoracic sympathectomy for axillary osmidrosis or bromidrosis. J Clin Neurosci. Sep 2004;11(7):719-22. [Medline].

  39. Goffin V, Arrese JE, Pierard-Franchimont C, Pierard GE. [Do you have a good nose? Small lexicon of bromhidroses and other body odors]. Rev Med Liege. Dec 1999;54(12):931-4. [Medline].

  40. Lockman DS. Olfactory diagnosis. Cutis. Jun 1981;27(6):645-7. [Medline].

  41. Park JH, Cha SH, Park SD. Carbon dioxide laser treatment vs subcutaneous resection of axillary osmidrosis. Dermatol Surg. Apr 1997;23(4):247-51. [Medline].

  42. Park YJ, Shin MS. What is the best method for treating osmidrosis?. Ann Plast Surg. Sep 2001;47(3):303-9. [Medline].

  43. Perng CK, Yeh FL, Ma H, et al. Is the treatment of axillary osmidrosis with liposuction better than open surgery?. Plast Reconstr Surg. Jul 2004;114(1):93-7. [Medline].

  44. Senol M, Fireman P. Body odor in dermatologic diagnosis. Cutis. Feb 1999;63(2):107-11. [Medline].

  45. Swartling C, Naver H, Pihl-Lundin I, Hagforsen E, Vahlquist A. Sweat gland morphology and periglandular innervation in essential palmar hyperhidrosis before and after treatment with intradermal botulinum toxin. J Am Acad Dermatol. Nov 2004;51(5):739-45. [Medline].

 
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