Trichorrhexis Nodosa Follow-up

  • Author: Robert A Schwartz, MD, MPH; Chief Editor: William D James, MD   more...
 
Updated: May 27, 2011
 

Deterrence/Prevention

Patients should avoid physical and chemical trauma to the hair shaft. See Pathophysiology.

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Prognosis

Acquired trichorrhexis nodosa is reversible with the avoidance of physical and chemical trauma. Complete resolution may take 2-4 years, depending on the growth of new anagen hairs.

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Contributor Information and Disclosures
Author

Robert A Schwartz, MD, MPH  Professor and Head, Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, University of Medicine and Dentistry of New Jersey-New Jersey Medical School

Robert A Schwartz, MD, MPH is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American College of Physicians, and Sigma Xi

Disclosure: Nothing to disclose.

Coauthor(s)

Bryan D Seiff, MD  Staff Physician, Department of Ophthalmology, NY Presbyterian Hospital-Cornell

Bryan D Seiff, MD is a member of the following medical societies: Alpha Omega Alpha

Disclosure: Nothing to disclose.

Specialty Editor Board

Leonard Sperling, MD  Chair, Professor, Department of Dermatology, Uniformed Services University of the Health Sciences

Leonard Sperling, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

David F Butler, MD  Professor of Dermatology, Texas A&M University College of Medicine; Chair, Department of Dermatology, Director, Dermatology Residency Training Program, Scott and White Clinic, Northside Clinic

David F Butler, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, American Society for Dermatologic Surgery, American Society for MOHS Surgery, Association of Military Dermatologists, and Phi Beta Kappa

Disclosure: Nothing to disclose.

Paul Krusinski, MD  Director of Dermatology, Fletcher Allen Health Care; Professor, Department of Internal Medicine, University of Vermont College of Medicine

Paul Krusinski, MD is a member of the following medical societies: American Academy of Dermatology, American College of Physicians, and Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Glen H Crawford, MD  Assistant Clinical Professor, Department of Dermatology, University of Pennsylvania School of Medicine; Chief, Division of Dermatology, The Pennsylvania Hospital

Glen H Crawford, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, Phi Beta Kappa, and Society of USAF Flight Surgeons

Disclosure: Nothing to disclose.

Chief Editor

William D James, MD  Paul R Gross Professor of Dermatology, University of Pennsylvania School of Medicine; Vice-Chair, Program Director, Department of Dermatology, University of Pennsylvania Health System

William D James, MD is a member of the following medical societies: American Academy of Dermatology and Society for Investigative Dermatology

Disclosure: Elsevier Royalty Other

References

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  4. Lurie R, Hodak E, Ginzburg A, David M. Trichorrhexis nodosa: a manifestation of hypothyroidism. Cutis. May 1996;57(5):358-9. [Medline].

  5. Hartley JL, Zachos NC, Dawood B, Donowitz M, Forman J, Pollitt RJ, et al. Mutations in TTC37 Cause Trichohepatoenteric Syndrome (Phenotypic Diarrhea of Infancy). Gastroenterology. Feb 20 2010;[Medline].

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  12. Khumalo NP, Dawber RP, Ferguson DJ. Apparent fragility of African hair is unrelated to the cystine-rich protein distribution: a cytochemical electron microscopic study. Exp Dermatol. Apr 2005;14(4):311-4. [Medline].

  13. Liang C, Kraemer KH, Morris A, Schiffmann R, Price VH, Menefee E, et al. Characterization of tiger-tail banding and hair shaft abnormalities in trichothiodystrophy. J Am Acad Dermatol. Feb 2005;52(2):224-32. [Medline].

  14. Cosimo QC, Daniela L, Elsa B, Carlo DV, Giuseppe F. Kinky hair, kinky vessels, and bladder diverticula in menkes disease. J Neuroimaging. Apr 2011;21(2):e114-6. [Medline].

  15. Burkhart CG, Burkhart CN. Trichorrhexis nodosa revisited. Skinmed. Mar-Apr 2007;6(2):57-8. [Medline].

  16. Freedburg IM, Eisen AZ, Wolff K, et al. Fitzpatrick's Dermatology in General Medicine. 5th ed. New York, NY: McGraw Hill; 1999.

  17. Leonard JN, Gummer CL, Dawber RP. Generalized trichorrhexis nodosa. Br J Dermatol. Jul 1980;103(1):85-90. [Medline].

  18. Owens DW, Chernosky ME. Trichorrhexis nodosa; in vitro reproduction. Arch Dermatol. Nov 1966;94(5):586-8. [Medline].

  19. Peter C, Tomczok J, Hoting E, Behrendt H. Trichothiodystrophy without associated neuroectodermal defects. Br J Dermatol. Jul 1998;139(1):137-40. [Medline].

  20. Rushton DH, Norris MJ, James KC. Amino-acid composition in trichorrhexis nodosa. Clin Exp Dermatol. Jan 1990;15(1):24-8. [Medline].

 
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