eMedicine Specialties > Dermatology > Diseases of the Oral Mucosa
Leukoplakia, Oral: Multimedia
Updated: Oct 17, 2008
Multimedia
![]() | Media file 1: Homogeneous leukoplakia. |
![]() | Media file 2: Erythroleukoplakia. |
![]() | Media file 3: Verrucous or nodular leukoplakia. |
![]() | Media file 4: Carcinoma referred to as a leukoplakia. |
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References
Warnakulasuriya S, Johnson NW, van der Waal I. Nomenclature and classification of potentially malignant disorders of the oral mucosa. J Oral Pathol Med. Nov 2007;36(10):575-80. [Medline].
Bouquot JE, Weiland LH, Kurland LT. Leukoplakia and carcinoma in situ synchronously associated with invasive oral/oropharyngeal carcinoma in Rochester, Minn., 1935-1984. Oral Surg Oral Med Oral Pathol. Feb 1988;65(2):199-207. [Medline].
Bagan JV, Jimenez Y, Sanchis JM, Poveda R, Milian MA, Murillo J, et al. Proliferative verrucous leukoplakia: high incidence of gingival squamous cell carcinoma. J Oral Pathol Med. Aug 2003;32(7):379-82. [Medline].
Bagán JV, Murillo J, Poveda R, Gavaldá C, Jiménez Y, Scully C. Proliferative verrucous leukoplakia: unusual locations of oral squamous cell carcinomas, and field cancerization as shown by the appearance of multiple OSCCs. Oral Oncol. Apr 2004;40(4):440-3. [Medline].
Fisher MA, Bouquot JE, Shelton BJ. Assessment of risk factors for oral leukoplakia in West Virginia. Community Dent Oral Epidemiol. Feb 2005;33(1):45-52. [Medline].
Allen CL, Loudon J, Mascarenhas AK. Sanguinaria-related leukoplakia: epidemiologic and clinicopathologic features of a recently described entity. Gen Dent. Nov-Dec 2001;49(6):608-14. [Medline].
Eversole LR, Eversole GM, Kopcik J. Sanguinaria-associated oral leukoplakia: comparison with other benign and dysplastic leukoplakic lesions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. Apr 2000;89(4):455-64. [Medline].
Jiang WW, Fujii H, Shirai T, Mega H, Takagi M. Accumulative increase of loss of heterozygosity from leukoplakia to foci of early cancerization in leukoplakia of the oral cavity. Cancer. Nov 1 2001;92(9):2349-56. [Medline].
Garewal HS, Katz RV, Meyskens F, Pitcock J, Morse D, Friedman S, et al. Beta-carotene produces sustained remissions in patients with oral leukoplakia: results of a multicenter prospective trial. Arch Otolaryngol Head Neck Surg. Dec 1999;125(12):1305-10. [Medline].
Chiesa F, Tradati N, Sala L, Costa L, Podrecca S, Boracchi P, et al. Follow-up of oral leukoplakia after carbon dioxide laser surgery. Arch Otolaryngol Head Neck Surg. Feb 1990;116(2):177-80. [Medline].
Chiesa F, Sala L, Costa L, Moglia D, Mauri M, Podrecca S, et al. Excision of oral leukoplakias by CO2 laser on an out-patient basis: a useful procedure for prevention and early detection of oral carcinomas. Tumori. Jun 30 1986;72(3):307-12. [Medline].
Sudbø J, Lippman SM, Lee JJ, Mao L, Kildal W, Sudbø A, et al. The influence of resection and aneuploidy on mortality in oral leukoplakia. N Engl J Med. Apr 1 2004;350(14):1405-13. [Medline].
Sudbø J, Kildal W, Risberg B, Koppang HS, Danielsen HE, Reith A. DNA content as a prognostic marker in patients with oral leukoplakia. N Engl J Med. Apr 26 2001;344(17):1270-8. [Medline].
Abdel-Salam M, Mayall BH, Chew K, Silverman S Jr, Greenspan JS. Prediction of malignant transformation in oral epithelial lesions by image cytometry. Cancer. Nov 1 1988;62(9):1981-7. [Medline].
Bouquot JE, Whitaker SB. Oral leukoplakia--rationale for diagnosis and prognosis of its clinical subtypes or "phases". Quintessence Int. Feb 1994;25(2):133-40. [Medline].
Bánóczy J. Follow-up studies in oral leukoplakia. J Maxillofac Surg. Feb 1977;5(1):69-75. [Medline].
Ikeda N, Ishii T, Iida S, Kawai T. Epidemiological study of oral leukoplakia based on mass screening for oral mucosal diseases in a selected Japanese population. Community Dent Oral Epidemiol. Jun 1991;19(3):160-3. [Medline].
Jaber MA, Porter SR, Speight P, Eveson JW, Scully C. Oral epithelial dysplasia: clinical characteristics of western European residents. Oral Oncol. Sep 2003;39(6):589-96. [Medline].
Kramer IR, Lucas RB, Pindborg JJ, Sobin LH. Definition of leukoplakia and related lesions: an aid to studies on oral precancer. Oral Surg Oral Med Oral Pathol. Oct 1978;46(4):518-39. [Medline].
Kulasegaram R, Downer MC, Jullien JA, Zakrzewska JM, Speight PM. Case-control study of oral dysplasia and risk habits among patients of a dental hospital. Eur J Cancer B Oral Oncol. Jul 1995;31B(4):227-31. [Medline].
Lumerman H, Freedman P, Kerpel S. Oral epithelial dysplasia and the development of invasive squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. Mar 1995;79(3):321-9. [Medline].
Marley JJ, Linden GJ, Cowan CG, Lamey PJ, Johnson NW, Warnakulasuriya KA, et al. A comparison of the management of potentially malignant oral mucosal lesions by oral medicine practitioners and oral & maxillofacial surgeons in the UK. J Oral Pathol Med. Nov 1998;27(10):489-95. [Medline].
McCarthy FP. Etiology, pathology and treatment of leukoplakia buccalis with a report of 316 cases. Arch Dermatol Syph. 1936;6:612-23.
Pentenero M, Carrozzo M, Pagano M, Galliano D, Broccoletti R, Scully C, et al. Oral mucosal dysplastic lesions and early squamous cell carcinomas: underdiagnosis from incisional biopsy. Oral Dis. Mar 2003;9(2):68-72. [Medline].
Sankaranarayanan R, Nair MK, Mathew B, Balaram P, Sebastian P, Dutt SC. Recent results of oral cancer research in Kerala, India. Head Neck. Mar-Apr 1992;14(2):107-12. [Medline].
Schepman K, der Meij E, Smeele L, der Waal I. Concomitant leukoplakia in patients with oral squamous cell carcinoma. Oral Dis. Jul 1999;5(3):206-9. [Medline].
Schepman KP, van der Waal I. A proposal for a classification and staging system for oral leukoplakia: a preliminary study. Eur J Cancer B Oral Oncol. Nov 1995;31B(6):396-8. [Medline].
Sciubba JJ. Oral leukoplakia. Crit Rev Oral Biol Med. 1995;6(2):147-60. [Medline].
Scully C, Cawson RA. Potentially malignant oral lesions. J Epidemiol Biostat. 1996;1:3-12.
Scully C, Sudbø J, Speight PM. Progress in determining the malignant potential of oral lesions. J Oral Pathol Med. May 2003;32(5):251-6. [Medline].
Silverman S Jr, Gorsky M, Lozada F. Oral leukoplakia and malignant transformation. A follow-up study of 257 patients. Cancer. Feb 1 1984;53(3):563-8. [Medline].
Szpirglas H. [Detection of oral cancers and current conception of precancerous conditions]. Rev Prat. Apr 1 1995;45(7):831-7. [Medline].
van der Waal RI, Pas HH, Nousari HC, Schulten EA, Jonkman MF, Nieboer C, et al. Paraneoplastic pemphigus caused by an epithelioid leiomyosarcoma and associated with fatal respiratory failure. Oral Oncol. Jul 2000;36(4):390-3. [Medline].
Waldron CA, Shafer WG. Leukoplakia revisited. A clinicopathologic study 3256 oral leukoplakias. Cancer. Oct 1975;36(4):1386-92. [Medline].
Wright JM. Oral precancerous lesions and conditions. Semin Dermatol. Jun 1994;13(2):125-31. [Medline].
Zavras AI, Laskaris C, Kittas C, Laskaris G. Leukoplakia and intraoral malignancies: female cases increase in Greece. J Eur Acad Dermatol Venereol. Jan 2003;17(1):25-7. [Medline].
Further Reading
Keywords
oral leukoplakia, leukoplakia, oral cancer, mouth cancer, smokeless tobacco, keratosis,








Multimedia: Leukoplakia, Oral