eMedicine Specialties > Dermatology > Diseases of the Oral Mucosa

Oral Pyogenic Granuloma: Differential Diagnoses & Workup

Author: John Svirsky, DDS, Director of Dental Diagnostic Services, Professor, Department of Oral Pathology, Virginia Commonwealth University School of Dentistry
Contributor Information and Disclosures

Updated: Oct 28, 2008

Differential Diagnoses

Peripheral Giant Cell Granuloma

Other Problems to Be Considered

Peripheral ossifying fibroma

Workup

Imaging Studies

Obtain a periapical radiograph of the associated teeth in lesions that involve the teeth. Radiography findings are negative if the lesion is a pyogenic granuloma. If calcifications are present, then the lesion probably is a peripheral ossifying fibroma, which is clinically identical to the pyogenic granuloma and requires the same treatment of removal with scaling of the adjacent teeth.

Histologic Findings

Histologic examination reveals sectioned soft tissue consisting of a lesion composed of ulcerated mucosa covering a core of cellular fibrous connective tissue admixed with proliferating vascular channels and a mixed inflammatory infiltrate. This lesion is a reactive/inflammatory process.

More on Oral Pyogenic Granuloma

Overview: Oral Pyogenic Granuloma
Differential Diagnoses & Workup: Oral Pyogenic Granuloma
Treatment & Medication: Oral Pyogenic Granuloma
Follow-up: Oral Pyogenic Granuloma
Multimedia: Oral Pyogenic Granuloma
References

References

  1. Sills ES, Zegarelli DJ, Hoschander MM, Strider WE. Clinical diagnosis and management of hormonally responsive oral pregnancy tumor (pyogenic granuloma). J Reprod Med. Jul 1996;41(7):467-70. [Medline].

  2. Vilmann A, Vilmann P, Vilmann H. Pyogenic granuloma: evaluation of oral conditions. Br J Oral Maxillofac Surg. Oct 1986;24(5):376-82. [Medline].

  3. Bhaskar SN, Jacoway JR. Pyogenic granuloma--clinical features, incidence, histology, and result of treatment: report of 242 cases. J Oral Surg. Sep 1966;24(5):391-8. [Medline].

  4. Eisen D, Lynch DP. The Mouth: Diagnosis and Treatment. St. Louis, Mo: Mosby; 1998:58-60.

  5. Neville BW, Damm DD, Allen CM, Bouquot JE. Oral & Maxillofacial Pathology. Philadelphia, Pa: WB Saunders; 2002:447-9.

  6. Neville BW, Damm DD, White DK. Color Atlas of Clinical Oral Pathology. Baltimore, Md: Lippincott Williams & Wilkins; 1999:284-5.

  7. Sapp JP, Eversole LR, Wysocki GP. Contemporary Oral and Maxillofacial Pathology. 2nd ed. St. Louis, Mo: Mosby; 2003.

Further Reading

Keywords

pyogenic granuloma, peripheral ossifying fibroma, peripheral giant cell granuloma, pregnancy tumor

Contributor Information and Disclosures

Author

John Svirsky, DDS, Director of Dental Diagnostic Services, Professor, Department of Oral Pathology, Virginia Commonwealth University School of Dentistry
John Svirsky, DDS is a member of the following medical societies: American Academy of Oral Medicine and American Dental Association
Disclosure: Nothing to disclose.

Medical Editor

Kelly M Cordoro, MD, Fellow and Clinical Instructor, Department of Pediatric Dermatology, University of California at San Francisco; Assistant Professor (On Educational Leave), Assistant Program Director for Resident Medical Education, Department of Dermatology, University of Virginia School of Medicine
Kelly M Cordoro, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, Association of Professors of Dermatology, Dermatology Foundation, Medical Society of Virginia, National Psoriasis Foundation, Society for Pediatric Dermatology, and Women's Dermatologic Society
Disclosure: Nothing to disclose.

Pharmacy Editor

Michael J Wells, MD, Associate Professor, Department of Dermatology, Texas Tech University Health Sciences Center
Michael J Wells, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, and Texas Medical Association
Disclosure: Nothing to disclose.

Managing Editor

Drore Eisen, MD, DDS, Consulting Staff, Department of Dermatology, Dermatology Research Associates of Cincinnati
Drore Eisen, MD, DDS is a member of the following medical societies: American Academy of Dermatology, American Academy of Oral Medicine, and American Dental Association
Disclosure: Nothing to disclose.

CME Editor

Glen H Crawford, MD, Assistant Clinical Professor, Department of Dermatology, University of Pennsylvania School of Medicine; Chief, Division of Dermatology, The Pennsylvania Hospital
Glen H Crawford, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, Phi Beta Kappa, and Society of USAF Flight Surgeons
Disclosure: Nothing to disclose.

Chief Editor

William D James, MD, Paul R Gross Professor of Dermatology, University of Pennsylvania School of Medicine; Vice-Chair, Program Director, Department of Dermatology, University of Pennsylvania Health System
William D James, MD is a member of the following medical societies: American Academy of Dermatology and Society for Investigative Dermatology
Disclosure: elsevier Royalty Other; american college of physicians Honoraria Other

 
 
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