Fissured Tongue Clinical Presentation
- Author: Robert D Kelsch, DMD; Chief Editor: William D James, MD more...
History
The lesions associated with fissured tongue are usually asymptomatic unless debris is entrapped within the fissure or when it occurs in association with geographic tongue (a common finding).
Physical
Upon clinical examination, fissured tongue affects the dorsum and often extends to the lateral borders of the tongue. The depth of the fissures varies but has been noted to be up to 6 mm in diameter. When particularly prominent, the fissures or grooves may be interconnected, separating the tongue dorsum into what may appear to be several lobules.
Causes
Although a specific etiology has not been elicited for fissured tongue, a polygenic or autosomal dominant mode of inheritance is suspected because fissured tongue is seen with increased frequency in families with an affected proband.[7]
Kaminagakura E, Jorge J Jr. Melkersson Rosenthal syndrome: a histopathologic mystery and dermatologic challenge. J Cutan Pathol. Oct 15 2009;[Medline].
Dar-Odeh NS, Hayajneh WA, Abu-Hammad OA, et al. Orofacial findings in chronic granulomatous disease: report of twelve patients and review of the literature. BMC Res Notes. Feb 17 2010;3(1):37. [Medline].
Stein SL, Mancini AJ. Melkersson-Rosenthal syndrome in childhood: successful management with combination steroid and minocycline therapy. J Am Acad Dermatol. Nov 1999;41(5 Pt 1):746-8. [Medline].
Alioglu Z, Caylan R, Adanir M, Ozmenoglu M. Melkersson-Rosenthal syndrome: report of three cases. Neurol Sci. Feb 2000;21(1):57-60. [Medline].
Gerressen M, Ghassemi A, Stockbrink G, Riediger D, Zadeh MD. Melkersson-Rosenthal syndrome: case report of a 30-year misdiagnosis. J Oral Maxillofac Surg. Jul 2005;63(7):1035-9. [Medline].
Kovac-Kovacic M, Skaleric U. The prevalence of oral mucosal lesions in a population in Ljubljana, Slovenia. J Oral Pathol Med. Aug 2000;29(7):331-5. [Medline].
Eidelman E, Chosack A, Cohen T. Scrotal tongue and geographic tongue: polygenic and associated traits. Oral Surg Oral Med Oral Pathol. Nov 1976;42(5):591-6. [Medline].
Rogers RS. Melkersson-Rosenthal syndrome and orofacial granulomatosis. Dermatol Clin. Apr 1996;14(2):371-9. [Medline].
Reamy BV, Derby R, Bunt CW. Common tongue conditions in primary care. Am Fam Physician. Mar 1 2010;81(5):627-34. [Medline].
Kullaa-Mikkonen A, Sorvari T. Lingua fissurata. A clinical, stereomicroscopic and histopathological study. Int J Oral Maxillofac Surg. Oct 1986;15(5):525-33. [Medline].
Nakane T, Hatakeyama K, Nakamura K, Aihara M, Nakazawa S. Melkersson-Rosenthal syndrome with isolated immunoglobulin E hypogammaglobulinaemia. J Int Med Res. Nov-Dec 2007;35(6):922-5. [Medline].
Shulman JD, Carpenter WM. Prevalence and risk factors associated with geographic tongue among US adults. Oral Dis. Jul 2006;12(4):381-6. [Medline].
Tan O, Atik B, Calka O. Plastic surgical solutions for melkersson-rosenthal syndrome: facial liposuction and cheiloplasty procedures. Ann Plast Surg. Mar 2006;56(3):268-73. [Medline].
Yarom N, Cantony U, Gorsky M. Prevalence of fissured tongue, geographic tongue and median rhomboid glossitis among Israeli adults of different ethnic origins. Dermatology. 2004;209(2):88-94. [Medline].

