eMedicine Specialties > Dermatology > Diseases of the Oral Mucosa
Oral Granular Cell Tumors: Treatment & Medication
Updated: Nov 12, 2008
- Overview
- Differential Diagnoses & Workup
- Treatment & Medication
- Follow-up
- Multimedia
Treatment
Medical Care
Treatment for granular cell tumors and congenital epulis is surgery. While extensive surgery is not indicated, recurrence of granular cell tumors has been reported several years after removal. Recurrence of congenital epulis has not been reported; however, the number of total cases is small.
Surgical Care
Excision with a scalpel under local anesthesia is the preferred method; however, surgical margins are difficult to determine intraoperatively in the case of the granular cell tumor. Excision down to the periosteum usually is the goal for treating congenital epulis; however, recurrence does not seem to occur even if this lesion is not completely removed.
Activity
Advise the patient with routine postoperative precautions.
Medication
No medications are efficacious.
More on Oral Granular Cell Tumors |
| Overview: Oral Granular Cell Tumors |
| Differential Diagnoses & Workup: Oral Granular Cell Tumors |
Treatment & Medication: Oral Granular Cell Tumors |
| Follow-up: Oral Granular Cell Tumors |
| Multimedia: Oral Granular Cell Tumors |
| References |
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References
Becelli R, Perugini M, Gasparini G, Cassoni A, Fabiani F. Abrikossoff's tumor. J Craniofac Surg. Jan 2001;12(1):78-81. [Medline].
Curtis BV, Calcaterra TC, Coulson WF. Multiple granular cell tumor: a case report and review of the literature. Head Neck. Oct 1997;19(7):634-7. [Medline].
Junquera LM, de Vicente JC, Vega JA, Losa JL, Albertos JM, López-Arranz JS. Granular-cell tumours: an immunohistochemical study. Br J Oral Maxillofac Surg. Jun 1997;35(3):180-4. [Medline].
Lapid O, Shaco-Levy R, Krieger Y, Kachko L, Sagi A. Congenital epulis. Pediatrics. Feb 2001;107(2):E22. [Medline].
Le BH, Boyer PJ, Lewis JE, Kapadia SB. Granular cell tumor: immunohistochemical assessment of inhibin-alpha, protein gene product 9.5, S100 protein, CD68, and Ki-67 proliferative index with clinical correlation. Arch Pathol Lab Med. Jul 2004;128(7):771-5. [Medline].
McGuire TP, Gomes PP, Freilich MM, Sándor GK. Congenital epulis: a surprise in the neonate. J Can Dent Assoc. Oct 2006;72(8):747-50. [Medline].
Nagaraj PB, Ongole R, Bhujanga-Rao BR. Granular cell tumor of the tongue in a 6-year-old girl--a case report. Med Oral Patol Oral Cir Bucal. Mar 2006;11(2):E162-164. [Medline].
Ordóñez NG. Granular cell tumor: a review and update. Adv Anat Pathol. Jul 1999;6(4):186-203. [Medline].
Philipp K, Barnes EL, Carrau RL. Eagle syndrome produced by a granular cell tumor. Arch Otolaryngol Head Neck Surg. Dec 2001;127(12):1499-1501. [Medline].
Stewart CM, Watson RE, Eversole LR, Fischlschweiger W, Leider AS. Oral granular cell tumors: a clinicopathologic and immunocytochemical study. Oral Surg Oral Med Oral Pathol. Apr 1988;65(4):427-35. [Medline].
Further Reading
Keywords
granular cell myoblastoma, granular cell schwannoma, Abrikossoff tumor, Abrikossoff’s tumor, tumor of Abrikossoff, granular cell neurofibroma
Treatment & Medication: Oral Granular Cell Tumors