eMedicine Specialties > Dermatology > Diseases of the Oral Mucosa

Oral Florid Papillomatosis: Follow-up

Author: Robert A Schwartz, MD, MPH, Professor and Head, Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, UMDNJ-New Jersey Medical School
Coauthor(s): Channing R Barnett, MD, Staff Physician, Department of Dermatology, University of Medicine and Dentistry of New Jersey
Contributor Information and Disclosures

Updated: Jun 12, 2009

Follow-up

Further Outpatient Care

  • Patients with verrucous carcinoma (VC) should be carefully monitored because the following might develop:
    • Second cancer
    • Aggressive squamous cell carcinoma
    • Anaplastic transformation of a preexistent verrucous carcinoma

Complications

  • Verrucous carcinoma is a locally aggressive and destructive tumor that advances into adjacent bone and other structures.
  • Regional lymph node metastases occasionally occur, but distant metastases are rare.
  • Rapid anaplastic transformation with widespread metastases has been described in a few patients with oral verrucous carcinoma. This complication mainly occurs after radiation therapy.

Prognosis

  • See Mortality/Morbidity.
  • Three hundred and two patients with oral verrucous carcinoma in India were evaluated retrospectively.63 Early-stage tumors accounted for 39.7%; 60.4% were late-stage tumors. Sixty-eight percent (19 of 28) recurred locally; the salvage rate for recurrent tumors was 66.7% (16 of 28), with a median postrecurrence survival of 16 months (range, 10-83 mo). The 5-year disease-free survival rate after surgical therapy was 77.6%.

Patient Education

Miscellaneous

Medicolegal Pitfalls

  • A persistent wart or wartlike tumor should be evaluated to rule out verrucous carcinoma.
 


More on Oral Florid Papillomatosis

Overview: Oral Florid Papillomatosis
Differential Diagnoses & Workup: Oral Florid Papillomatosis
Treatment & Medication: Oral Florid Papillomatosis
Follow-up: Oral Florid Papillomatosis
References
[ CLOSE WINDOW ]

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Further Reading

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Keywords

oral florid papillomatosis, verrucous carcinoma, Ackerman's tumor, Ackerman tumor, carcinoid mucous papillomatosis, oral cavity and aerodigestive tract verrucous carcinoma, oral florid verrucosis, giant mucocutaneous papillomatosis, nonmetastasizing papillomatosis, squamous cell carcinoma, multifocal papillomavirus epithelial hyperplasia

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Contributor Information and Disclosures

Author

Robert A Schwartz, MD, MPH, Professor and Head, Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, UMDNJ-New Jersey Medical School
Robert A Schwartz, MD, MPH is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American College of Physicians, and Sigma Xi
Disclosure: Nothing to disclose.

Coauthor(s)

Channing R Barnett, MD, Staff Physician, Department of Dermatology, University of Medicine and Dentistry of New Jersey
Channing R Barnett, MD is a member of the following medical societies: Sigma Xi
Disclosure: Nothing to disclose.

Medical Editor

Julie C Harper, MD, Assistant Program Director, Assistant Professor, Department of Dermatology, University of Alabama at Birmingham
Julie C Harper, MD is a member of the following medical societies: American Academy of Dermatology
Disclosure: Stiefel Honoraria Speaking and teaching; Allergan Honoraria Speaking and teaching; Intendis Honoraria Speaking and teaching; Coria Honoraria Speaking and teaching; Sanofi-Aventis Honoraria Speaking and teaching

Pharmacy Editor

David F Butler, MD, Professor of Dermatology, Texas A&M University College of Medicine; Chair, Department of Dermatology, Director, Dermatology Residency Training Program, Scott and White Clinic, Northside Clinic
David F Butler, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, American Society for Dermatologic Surgery, American Society for MOHS Surgery, Association of Military Dermatologists, and Phi Beta Kappa
Disclosure: Nothing to disclose.

Managing Editor

Drore Eisen, MD, DDS, Consulting Staff, Department of Dermatology, Dermatology Research Associates of Cincinnati
Drore Eisen, MD, DDS is a member of the following medical societies: American Academy of Dermatology, American Academy of Oral Medicine, and American Dental Association
Disclosure: Nothing to disclose.

CME Editor

Joel M Gelfand, MD, MSCE, Medical Director, Clinical Studies Unit, Assistant Professor, Department of Dermatology, Associate Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania
Joel M Gelfand, MD, MSCE is a member of the following medical societies: Society for Investigative Dermatology
Disclosure: AMGEN Consulting fee Consulting; AMGEN Grant/research funds None; Genentech Consulting fee Consulting; Centocor Consulting fee Consulting; Centocor Grant/research funds None; Covance Consulting fee Consulting; Shire  Consulting

Chief Editor

Dirk M Elston, MD, Director, Department of Dermatology, Geisinger Medical Center
Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology
Disclosure: Nothing to disclose.

 
 
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