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Piezogenic Pedal Papules Differential Diagnoses

  • Author: Christopher R Gorman, MD; Chief Editor: William D James, MD  more...
Updated: Sep 22, 2015

Diagnostic Considerations

Infantile pedal papules are fairly common, nontender, congenital nodules located on the medial plantar aspects of the foot. This condition has been described as precalcaneal congenital fibrolipomatosis hamartomas, bilateral congenital adipose plantar nodules, benign anteromedial plantar nodules of childhood, congenital piezogeniclike pedal papules, bilateral congenital fatty heel pads, and pedal papules of the newborn. They are most common at age 1 year and typically disappear between ages 2 and 3 years. Infantile pedal papules do not accentuate upon standing. The etiology is unknown.

Autosomal dominant precalcaneal congenital fibrolipomatous hamartoma is rare.[7, 8] Lesions were flesh colored and in the midline of each heel (plantar). They are symmetric and bilateral. These persisted up to puberty and beyond (age 20 y) in one case. Histologically, they are mature adipose tissue. No other associated malformations were reported.

Contributor Information and Disclosures

Christopher R Gorman, MD Avenues Dermatology, Private Practice

Christopher R Gorman, MD is a member of the following medical societies: Alpha Omega Alpha

Disclosure: Nothing to disclose.

Specialty Editor Board

Richard P Vinson, MD Assistant Clinical Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine; Consulting Staff, Mountain View Dermatology, PA

Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Texas Medical Association, Association of Military Dermatologists, Texas Dermatological Society

Disclosure: Nothing to disclose.

Lester F Libow, MD Dermatopathologist, South Texas Dermatopathology Laboratory

Lester F Libow, MD is a member of the following medical societies: American Academy of Dermatology, American Society of Dermatopathology, Texas Medical Association

Disclosure: Nothing to disclose.

Chief Editor

William D James, MD Paul R Gross Professor of Dermatology, Vice-Chairman, Residency Program Director, Department of Dermatology, University of Pennsylvania School of Medicine

William D James, MD is a member of the following medical societies: American Academy of Dermatology, Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Additional Contributors

Kathryn Schwarzenberger, MD Associate Professor of Medicine, Division of Dermatology, University of Vermont College of Medicine; Consulting Staff, Division of Dermatology, Fletcher Allen Health Care

Kathryn Schwarzenberger, MD is a member of the following medical societies: Women's Dermatologic Society, American Contact Dermatitis Society, Medical Dermatology Society, Dermatology Foundation, Alpha Omega Alpha, American Academy of Dermatology

Disclosure: Nothing to disclose.



Medscape Drugs & Diseases wishes to recognize Stephen W White, MD† for his original contributions to this article.

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