Introduction
Background
Cherry hemangiomas are the most common cutaneous vascular proliferations. They are often widespread and appear as tiny cherry red papules or macules.
Pathophysiology
Involvement of cherry hemangiomas is limited to the skin. These benign lesions are formed by a proliferation of dilated venules.
Frequency
United States
Frequency of cherry hemangiomas increases with age in both sexes and all races.
International
The incidence of cherry angiomas is uniform across all races, but individual lesions are most noticeable in pale-skinned individuals.
Mortality/Morbidity
- Lesions are benign and usually do not undergo spontaneous involution.
- Patients may demonstrate considerable concern regarding the cosmetic appearance of the lesions.
Race
Cherry hemangiomas are found in individuals of all races and ethnic backgrounds.
Sex
No distinction can be made on the basis of sex.
Age
Cherry hemangiomas occur more frequently with increasing age. In the past, the lesions often were referred to as senile angiomas.
Clinical
History
Cherry angiomas typically present in the third or fourth decades of life, and early lesions may appear as small red macules.
- Lesions may be found on all body sites, but usually, the mucous membranes are spared.
- Most patients report an increase in number and size of individual lesions with advancing age.
Physical
On physical examination, lesions may have a variable appearance, ranging from a small red macule to a larger dome-topped or polypoid papule.
- The color of the lesions typically is described as bright cherry red, but the lesions may appear more violaceous at times (see Media File 1).
- Rarely, a lesion demonstrates a dark brown to an almost black color when a hemorrhagic plug occupies the vascular lumen, often raising concern about the possibility of a malignant melanoma.
Causes
Little is known about the factors that contribute to the formation of cherry hemangiomas. Several reports have described the appearance of many small red papules histologically resembling cherry hemangiomas in patients with malignancies,1 although most lesions occur in healthy patients.
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References
Pembroke AC, Grice K, Levantine AV, Warin AP. Eruptive angiomata in malignant disease. Clin Exp Dermatol. Jun 1978;3(2):147-56. [Medline].
Dawn G, Gupta G. Comparison of potassium titanyl phosphate vascular laser and hyfrecator in the treatment of vascular spiders and cherry angiomas. Clin Exp Dermatol. Nov 2003;28(6):581-3. [Medline].
Gupta G, Bilsland D. A prospective study of the impact of laser treatment on vascular lesions. Br J Dermatol. Aug 2000;143(2):356-9. [Medline].
Calonje E, Wilson-Jones E. Vascular tumors: tumors and tumor-like conditions of blood vessels and lymphatics. In: Elder D, Elenitsas R, Jaworsky C, Johnson B Jr, eds. Lever's Histopathology of the Skin. 8th ed. Philadelphia, Pa: Lippincott-Raven; 1997:902.
Hagiwara K, Khaskhely NM, Uezato H, Nonaka S. Mast cell "densities" in vascular proliferations: a preliminary study of pyogenic granuloma, portwine stain, cavernous hemangioma, cherry angioma, Kaposi's sarcoma, and malignant hemangioendothelioma. J Dermatol. Sep 1999;26(9):577-86. [Medline].
Mazereeuw-Hautier J, Cambon L, Bonafé JL. [Eruptive pseudoangiomatosis in an adult renal transplant recipient]. Ann Dermatol Venereol. Jan 2001;128(1):55-6. [Medline].
Odom RB, James WD, Berger TB. Dermal and subcutaneous tumors: cherry angiomas. In: Andrew's Diseases of the Skin: Clinical Dermatology. 2000. 9th ed. Philadelphia, Pa: WB Saunders; 2000:751.
Sanchez JL, Ackerman AB. Vascular proliferations of skin and subcutaneous tissue. In: Fitzpatrick's Dermatology in General Medicine. Vol 1. New York, NY: McGraw-Hill; 1993:1219-20.
Further Reading
Keywords
Campbell de Morgan spots, senile angiomas
Overview: Cherry Hemangioma