eMedicine Specialties > Dermatology > Diseases of the Vessels

Churg-Strauss Syndrome (Allergic Granulomatosis): Multimedia

Author: Claudia Hernandez, MD, Assistant Professor, Department of Dermatology, University of Illinois at Chicago College of Medicine
Contributor Information and Disclosures

Updated: Oct 26, 2009

Multimedia

Granuloma with a central core of eosinophilic deb...Media file 1: Granuloma with a central core of eosinophilic debris surrounded by a peripheral palisade of epithelioid histiocytes and eosinophils.
Granuloma with a central core of eosinophilic deb...

Granuloma with a central core of eosinophilic debris surrounded by a peripheral palisade of epithelioid histiocytes and eosinophils.

Bilateral papules and nodules with central necros...Media file 2: Bilateral papules and nodules with central necrosis.
Bilateral papules and nodules with central necros...

Bilateral papules and nodules with central necrosis.

Magnified view of papules and nodules with centra...Media file 3: Magnified view of papules and nodules with central necrosis.
Magnified view of papules and nodules with centra...

Magnified view of papules and nodules with central necrosis.

Distal digital purpuric papule.Media file 4: Distal digital purpuric papule.
Distal digital purpuric papule.

Distal digital purpuric papule.

More on Churg-Strauss Syndrome (Allergic Granulomatosis)

Overview: Churg-Strauss Syndrome (Allergic Granulomatosis)
Differential Diagnoses & Workup: Churg-Strauss Syndrome (Allergic Granulomatosis)
Treatment & Medication: Churg-Strauss Syndrome (Allergic Granulomatosis)
Follow-up: Churg-Strauss Syndrome (Allergic Granulomatosis)
Multimedia: Churg-Strauss Syndrome (Allergic Granulomatosis)
References

References

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  2. Churg J, Strauss L. Allergic granulomatosis, alletic angiitis, and periarteritis nodosa. Am J Pathol. 1951;27:277.

  3. Oh MJ, Lee JY, Kwon NH, Choi DC. Churg-Strauss syndrome: the clinical features and long-term follow-up of 17 patients. J Korean Med Sci. Apr 2006;21(2):265-71. [Medline].

  4. Gota CE, Mandell BF. Systemic necrotizing vasculitis. In: Wolff K, Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ. Fitzpatrick's Dermatology in General Medicine. 2. 7th. New York: McGraw Hill; 2008:1606-1616/165.

  5. Katzenstein AL. Diagnostic features and differential diagnosis of Churg-Strauss syndrome in the lung. A review. Am J Clin Pathol. Nov 2000;114(5):767-72. [Medline].

  6. Masi AT, Hunder GG, Lie JT, et al. The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis). Arthritis Rheum. Aug 1990;33(8):1094-100. [Medline].

  7. Piette WW. Primary systemic vasculitis. In: Sontheimer RD, Provost TT. Cutaneous manifestations of rheumatic diseases. 2nd. New York: Lippincott Williams & Wilkins; 2004:159-196/ Chp 8.

  8. Pagnoux C, Guilpain P, Guillevin L. Churg-Strauss syndrome. Curr Opin Rheumatol. Jan 2007;19(1):25-32. [Medline].

  9. Phillip R, and Lugmani R. Mortaility in systemic vasculitis: a systemic review. Clin Exp Rheumatol. 2008;26 (5 Suppl 51):S94-104.

  10. Lhote F, Guillevin L. Polyarteritis nodosa, microscopic polyangiitis, and Churg-Strauss syndrome. Clinical aspects and treatment. Rheum Dis Clin North Am. Nov 1995;21(4):911-47. [Medline].

  11. Neumann T, Manger B, Schmid M, Kroegel C, Hansch A, Kaiser WA. Cardiac involvement in Churg-Strauss syndrome: impact of endomyocarditis. Medicine (Baltimore). Jul 2009;88(4):236-43. [Medline].

  12. Kahn JE, Bletry O, Guillevin L. Hypereosinophilic syndromes. Best Pract Res Clin Rheumatol. Oct 2008;22(5):863-82. [Medline].

  13. Wong DA, Miller MK, Lawrence-Miyasaki L. Churg-Strauss Syndrome in patients treated with omalizumab. Chest [serial online]. May 2009;May 2009:Accessed July 15, 2009. [Medline]. Available at http://www.chestjournal.org/content/early/2009/05/01/chest.08-2990.long.

  14. Keogh KA, Specks U. Churg-Strauss syndrome: clinical presentation, antineutrophil cytoplasmic antibodies, and leukotriene receptor antagonists. Am J Med. Sep 2003;115(4):284-90. [Medline].

  15. Peen E, Hahn P, Lauwers G, Williams RC Jr, Gleich G, Kephart GM. Churg-Strauss syndrome: localization of eosinophil major basic protein in damaged tissues. Arthritis Rheum. Aug 2000;43(8):1897-900. [Medline].

  16. Kaushik VV, Reddy HV, Bucknall RC. Successful use of rituximab in a patient with recalcitrant Churg-Strauss Syndrome. Ann Rheum Dis. Aug 2006;65(8):1116-7. [Medline].

  17. [Guideline] Global Initiative for Asthma. Global strategy for asthma management and prevention. National Guideline Clearinghouse. 2008.

Further Reading

Keywords

Churg-Strauss syndrome, allergic granulomatosis, CSS, allergic granulomatosis and angiitis, allergic granulomatous angiitis, asthma, transient pulmonary infiltrates, hypereosinophilia, systemic vasculitis, allergic rhinitis, peripheral blood eosinophilia

Contributor Information and Disclosures

Author

Claudia Hernandez, MD, Assistant Professor, Department of Dermatology, University of Illinois at Chicago College of Medicine
Claudia Hernandez, MD is a member of the following medical societies: American Academy of Dermatology, American Society for Dermatologic Surgery, American Society for Laser Medicine and Surgery, Chicago Dermatological Society, Chicago Medical Society, Dermatology Foundation, National Hispanic Medical Association, and Society for Investigative Dermatology
Disclosure: Amgen Honoraria Speaking and teaching; Centocor Honoraria Speaking and teaching

Medical Editor

Jacek C Szepietowski, MD, PhD, Professor, Vice-Head, Department of Dermatology, Venereology and Allergology, Wroclaw Medical University; Director of the Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Poland
Disclosure: Stiefel Salary Employment; Orfagen Consulting fee Consulting; Maruho Consulting fee Consulting; Astellas Consulting fee Consulting

Pharmacy Editor

David F Butler, MD, Professor of Dermatology, Texas A&M University College of Medicine; Chair, Department of Dermatology, Director, Dermatology Residency Training Program, Scott and White Clinic, Northside Clinic
David F Butler, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, American Society for Dermatologic Surgery, American Society for MOHS Surgery, Association of Military Dermatologists, and Phi Beta Kappa
Disclosure: Nothing to disclose.

Managing Editor

Edward F Chan, MD, Clinical Assistant Professor, Department of Dermatology, University of Pennsylvania School of Medicine
Edward F Chan, MD is a member of the following medical societies: American Academy of Dermatology, American Society of Dermatopathology, and Society for Investigative Dermatology
Disclosure: Nothing to disclose.

CME Editor

Catherine M Quirk, MD, Clinical Assistant Professor, Department of Dermatology, University of Pennsylvania
Catherine M Quirk, MD is a member of the following medical societies: Alpha Omega Alpha and American Academy of Dermatology
Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD, Director, Department of Dermatology, Geisinger Medical Center
Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology
Disclosure: Nothing to disclose.

 
 
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