eMedicine Specialties > Dermatology > Diseases of the Vessels

Erythema Induratum (Nodular Vasculitis): Follow-up

Author: Noah S Scheinfeld, MD, JD, FAAD, Assistant Clinical Professor, Department of Dermatology, Columbia University; Consulting Staff, Department of Dermatology, St Luke's Roosevelt Hospital Center, Beth Israel Medical Center, New York Eye and Ear Infirmary; Private Practice
Coauthor(s): Kwang-Hyun Cho, MD, Professor, Department of Dermatology, Seoul National University College of Medicine, Korea; Beom Joon Kim, Clinical Fellow, Clinical Fellow of Dermatology, Department of Dermatology, Seoul National University Hospital
Contributor Information and Disclosures

Updated: Mar 17, 2008

Follow-up

Complications

  • Inadequately treated or untreated erythema induratum may result in prolonged disease, persistent ulcerations, and complications due to coexistent systemic tuberculosis.

Prognosis

  • The prognosis is good if treated properly.

Miscellaneous

Medicolegal Pitfalls

  • A thorough understanding of the various adverse effects of antituberculous medications, including hepatotoxicity, is required.
 


More on Erythema Induratum (Nodular Vasculitis)

Overview: Erythema Induratum (Nodular Vasculitis)
Differential Diagnoses & Workup: Erythema Induratum (Nodular Vasculitis)
Treatment & Medication: Erythema Induratum (Nodular Vasculitis)
Follow-up: Erythema Induratum (Nodular Vasculitis)
Multimedia: Erythema Induratum (Nodular Vasculitis)
References

References

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  2. Ho CK, Ho MH, Chong LY. Cutaneous tuberculosis in Hong Kong: an update. Hong Kong Med J. Aug 2006;12(4):272-7. [Medline].

  3. Inoue T, Fukumoto T, Ansai S, Kimura T. Erythema induratum of Bazin in an infant after Bacille Calmette-Guerin vaccination. J Dermatol. Apr 2006;33(4):268-72. [Medline].

  4. Leahy TR, Downey P, Ramsay B, Philip RK. Erythema induratum of Bazin and episcleritis in a 6 year old girl. Arch Dis Child. Nov 2005;90(11):1132. [Medline].

  5. Friedman PC, Husain S, Grossman ME. Nodular tuberculid in a patient with HIV. J Am Acad Dermatol. Aug 2005;53(2 Suppl 1):S154-6. [Medline].

  6. Daher Ede F, Silva Junior GB, Pinheiro HC, Oliveira TR, Vilar Mdo L, Alcantara KJ. Erythema induratum of Bazin and renal tuberculosis: report of an association. Rev Inst Med Trop Sao Paulo. Sept-Oct 2004;46(5):295-8. [Medline].

  7. Silva MT, Antunes SL, Rolla VC, Galhardo MC, Sant'ana FM, do Valle AF. Distal painful peripheral neuropathy associated with erythema induratum of Bazin. Eur J Neurol. Dec 2006;13(12):e5-6. [Medline].

  8. Ramdial PK, Calonje E, Sydney C, Subrayen S, Meyiwa PS, Aboobaker J. Tuberculids as sentinel lesions of tuberculous epididymo-orchitis. J Cutan Pathol. Nov 2007;34(11):830-6. [Medline].

  9. Sughimoto K, Nakano K, Gomi A, Nakatani H, Nakamura Y, Sato A, et al. Aortic valve stenosis associated with Bazin's disease. J Heart Valve Dis. Mar 2007;16(2):212-3. [Medline].

  10. Degonda Halter M, Nebiker P, Hug B, Oberholzer M, Fluckiger U, Bassetti S. [Atypical erythema induratum Bazin with tuberculous osteomyelitis]. Internist (Berl). Aug 2006;47(8):853-6. [Medline].

  11. Jacinto SS, Nograles KB. Erythema induratum of bazin: role of polymerase chain reaction in diagnosis. Int J Dermatol. May 2003;42(5):380-1. [Medline].

  12. Chen YH, Yan JJ, Chao SC, Lee JY. Erythema induratum: a clinicopathologic and polymerase chain reaction study. J Formos Med Assoc. Apr 2001;100(4):244-9. [Medline].

  13. Schneider JW, Jordaan HF, Geiger DH, Victor T, Van Helden PD, Rossouw DJ. Erythema induratum of Bazin. A clinicopathological study of 20 cases and detection of Mycobacterium tuberculosis DNA in skin lesions by polymerase chain reaction. Am J Dermatopathol. Aug 1995;17(4):350-6. [Medline].

  14. Angus J, Roberts C, Kulkarni K, Leach I, Murphy R. Usefulness of the QuantiFERON test in the confirmation of latent tuberculosis in association with erythema induratum. Br J Dermatol. Dec 2007;157(6):1293-4. [Medline].

  15. Alothman A, Al Qahtani M, Al-Khenaizan S. Erythema induratum: what is the role of Mycobacterium tuberculosis?. Ann Saudi Med. Jul-Aug 2007;27(4):298-300. [Medline].

  16. Baselga E, Margall N, Barnadas MA, Coll P, de Moragas JM. Detection of Mycobacterium tuberculosis DNA in lobular granulomatous panniculitis (erythema induratum-nodular vasculitis). Arch Dermatol. Apr 1997;133(4):457-62. [Medline].

  17. Bennett NM. Erythema induratum: a case of mistaken identity. Med J Aust. Mar 20 2006;184(6):306; author reply 306-7. [Medline].

  18. Chanet V, Amarger S, Pons B, Dechelotte P, Ruivard M, Philippe P. [Nodular thrombophlebitis and granulomatous systemic disease.]. Rev Med Interne. Jun 2007;28(6):416-419. [Medline].

  19. Cho KH, Lee DY, Kim CW. Erythema induratum of Bazin. Int J Dermatol. Nov 1996;35(11):802-8. [Medline].

  20. Hay RJ. Cutaneous infection with Mycobacterium tuberculosis: how has this altered with the changing epidemiology of tuberculosis?. Curr Opin Infect Dis. Apr 2005;18(2):93-5. [Medline].

  21. Heymann WR. Panniculitis. J Am Acad Dermatol. Apr 2005;52(4):683-5. [Medline].

  22. Koga T, Kubota Y, Kiryu H, Nakayama J, Matsuzoe D, Shirakusa T. Erythema induratum in a patient with active tuberculosis of the axillary lymph node: IFN-gamma release of specific T cells. Eur J Dermatol. Jan-Feb 2001;11(1):48-9. [Medline].

  23. Requena L. Normal subcutaneous fat, necrosis of adipocytes and classification of the panniculitides. Semin Cutan Med Surg. Jun 2007;26(2):66-70. [Medline].

  24. Schneider JW, Jordaan HF. The histopathologic spectrum of erythema induratum of Bazin. Am J Dermatopathol. Aug 1997;19(4):323-33. [Medline].

  25. White WL. On Japanese baseball and erythema induratum of Bazin. Am J Dermatopathol. Aug 1997;19(4):318-22. [Medline].

  26. Wiebels D, Turnbull K, Steinkraus V, Boer A. [Erythema induratum Bazin : "Tuberculid" or tuberculosis.]. Hautarzt. Mar 2007;58(3):237-240. [Medline].

Further Reading

Keywords

tuberculosis-associated erythema induratum, TB-associated erythema induratum, erythema induratum of Bazin

Contributor Information and Disclosures

Author

Noah S Scheinfeld, MD, JD, FAAD, Assistant Clinical Professor, Department of Dermatology, Columbia University; Consulting Staff, Department of Dermatology, St Luke's Roosevelt Hospital Center, Beth Israel Medical Center, New York Eye and Ear Infirmary; Private Practice
Noah S Scheinfeld, MD, JD, FAAD is a member of the following medical societies: American Academy of Dermatology
Disclosure: Optigenex Consulting fee Independent contractor

Coauthor(s)

Kwang-Hyun Cho, MD, Professor, Department of Dermatology, Seoul National University College of Medicine, Korea
Disclosure: Nothing to disclose.

Beom Joon Kim, Clinical Fellow, Clinical Fellow of Dermatology, Department of Dermatology, Seoul National University Hospital
Disclosure: Nothing to disclose.

Medical Editor

Jean-Hilaire Saurat, MD, Chair, Professor, Department of Dermatology, University of Geneva, Switzerland
Jean-Hilaire Saurat, MD is a member of the following medical societies: American Academy of Dermatology, American Dermatological Association, and Society for Investigative Dermatology
Disclosure: Nothing to disclose.

Pharmacy Editor

Richard P Vinson, MD, Assistant Clinical Professor, Department of Dermatology, Texas Tech University School of Medicine; Consulting Staff, Mountain View Dermatology, PA
Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Association of Military Dermatologists, Texas Dermatological Society, and Texas Medical Association
Disclosure: Nothing to disclose.

Managing Editor

Lester F Libow, MD, Dermatopathologist, South Texas Dermatopathology Laboratory
Lester F Libow, MD is a member of the following medical societies: American Academy of Dermatology, American Society of Dermatopathology, and Texas Medical Association
Disclosure: Nothing to disclose.

CME Editor

Joel M Gelfand, MD, MSCE, Medical Director, Clinical Studies Unit, Assistant Professor, Department of Dermatology, Associate Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania
Joel M Gelfand, MD, MSCE is a member of the following medical societies: Society for Investigative Dermatology
Disclosure: AMGEN Consulting fee Consulting; AMGEN Grant/research funds None; Genentech Consulting fee Consulting; Centocor Consulting fee Consulting; Centocor Grant/research funds None; Covance Consulting fee Consulting; Shire  Consulting

Chief Editor

William D James, MD, Paul R Gross Professor of Dermatology, University of Pennsylvania School of Medicine; Vice-Chair, Program Director, Department of Dermatology, University of Pennsylvania Health System
William D James, MD is a member of the following medical societies: American Academy of Dermatology and Society for Investigative Dermatology
Disclosure: elsevier Royalty Other; american college of physicians Honoraria Other

 
 
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