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Capillary Malformation Differential Diagnoses

  • Author: Richard J Antaya, MD; Chief Editor: Dirk M Elston, MD  more...
 
Updated: Aug 20, 2014
 
 

Diagnostic Considerations

See the list below:

  • Early infantile hemangiomas: Consider a diagnosis of infantile hemangiomas before the onset of rapid proliferation. Infantile hemangiomas are easily differentiated from capillary malformations by the observation of rapid growth in the hemangiomas.
  • Abortive (telangiectatic) infantile hemangiomas: These usually are flat, pink patches with obvious telangiectases running throughout the lesion. These involute slowly over time, albeit slower than typical infantile hemangiomas.
  • Nevus flammeus neonatorum: Synonyms include salmon patch, stork bite, angel kiss, nevus simplex, nevus flammeus nuchae, medial or midline telangiectatic nevus, medial nevus flammeus, and physiologic capillary malformation. They occur on the midline glabella, the nose, the upper lip, the occipital scalp, or the eyelids. They are usually lighter pink than capillary malformations, with rates of 42% in white neonates and 31% in black neonates. In most cases, the anterior facial lesions lighten or resolve by the time the patient is aged 1-2 years; however, the occipital and lumbar lesions may persist throughout life.
  • Beckwith-Wiedemann syndrome
  • Coats disease: Retinal telangiectasia (usually unilateral) is rarely reported with an ipsilateral facial capillary malformation.
  • Cobb syndrome: See Physical.
  • Parkes-Weber syndrome: See Physical.
  • Phacomatosis pigmentovascularis
  • Roberts syndrome: This is characterized by facial capillary malformation, hypomelia, hypotrichosis, cleft lip, and growth retardation.
  • TAR syndrome: This is characterized by congenital thrombocytopenia, bilateral absence or hypoplasia of the radius, and capillary malformations.
  • Sturge-Weber syndrome: See Physical.
  • von Hippel-Lindau disease
  • Wyburn-Mason syndrome: See Physical.

Differential Diagnoses

 
 
Contributor Information and Disclosures
Author

Richard J Antaya, MD Director of Pediatric Dermatology, Professor, Departments of Dermatology and Pediatrics, Yale University School of Medicine

Richard J Antaya, MD is a member of the following medical societies: American Academy of Dermatology, Society for Pediatric Dermatology, American Academy of Pediatrics

Disclosure: Nothing to disclose.

Specialty Editor Board

Richard P Vinson, MD Assistant Clinical Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine; Consulting Staff, Mountain View Dermatology, PA

Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Texas Medical Association, Association of Military Dermatologists, Texas Dermatological Society

Disclosure: Nothing to disclose.

Van Perry, MD Assistant Professor, Department of Medicine, Division of Dermatology, University of Texas School of Medicine at San Antonio

Van Perry, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Additional Contributors

Mark W Cobb, MD Consulting Staff, WNC Dermatological Associates

Mark W Cobb, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Society of Dermatopathology

Disclosure: Nothing to disclose.

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Histopathologic features of a capillary malformation (nevus flammeus) showing telangiectatic vessels lined by mature-appearing endothelial cells.
Capillary malformation on the left preauricular aspect of the cheek, the ear, and the neck in a neonate (same patient as in Media Files 3-4).
Same patient as in Media Files 2 and 4 immediately after test spots with the pulsed-dye laser at 585 nm. Note the purpuric macules where the laser impacted in a linear distribution on the preauricular aspect of the cheek.
Same patient as in Media Files 2-3 after 4 treatments with the pulsed-dye laser. Treatments were given at 2-month intervals in an outpatient setting using topical anesthetic.
 
 
 
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