eMedicine Specialties > Dermatology > Diseases of the Vessels
Temporal (Giant Cell) Arteritis: Follow-up
Updated: May 29, 2009
Follow-up
Deterrence/Prevention
- Sun avoidance and protection of the head and the face from photodamage may eventually prove to be important preventive measures for temporal arteritis (TA).
Complications
- Ophthalmic complications are common.
- Clinical manifestations include visual disturbances, amaurosis fugax, diplopia, and blindness.
- Visual loss may be temporary or permanent and partial or complete in either one eye or both eyes.
- Blindness usually occurs abruptly and painlessly.
- Ischemic optic neuritis with eventual optic atrophy is the most common cause of visual loss and occurs in 15% of patients.
- Mesenteric vasculitis resulting in small bowel infarction has rarely been described in persons with temporal arteritis, but it represents a serious and potentially treatable complication.17
Prognosis
- Overall, with prompt diagnosis and treatment, temporal arteritis is a well-controlled disease. Symptoms from temporal arteritis improve within days of treatment. Corticosteroids can usually be tapered within the first 4-6 weeks and eventually discontinued. The prognosis for patients is excellent.
- Some patients' conditions respond well, but damage prior to treatment is irreversible.
- Rarely, a response to steroid therapy does not occur or doses cannot be tapered. Cytotoxic or immunosuppressive drugs have been recommended, but more data are needed.
Miscellaneous
Medicolegal Pitfalls
- Improper technique during TABx can rarely result in facial nerve damage. Understanding the temporal anatomic danger zone and planning the procedure accordingly, with execution within the superficial temporal fascia, can prevent nerve injury.
More on Temporal (Giant Cell) Arteritis |
| Overview: Temporal (Giant Cell) Arteritis |
| Differential Diagnoses & Workup: Temporal (Giant Cell) Arteritis |
| Treatment & Medication: Temporal (Giant Cell) Arteritis |
Follow-up: Temporal (Giant Cell) Arteritis |
| References |
| « Previous Page |
References
O'Brien JP, Regan W. Actinically degenerate elastic tissue is the likely antigenic basis of actinic granuloma of the skin and of temporal arteritis. J Am Acad Dermatol. Feb 1999;40(2 Pt 1):214-22. [Medline].
Weyand CM, Goronzy JJ. Medium- and large-vessel vasculitis. N Engl J Med. Jul 10 2003;349(2):160-9. [Medline].
Salvarani C, Pipitone N, Boiardi L, Hunder GG. Do we need treatment with tumour necrosis factor blockers for giant cell arteritis?. Ann Rheum Dis. May 2008;67(5):577-9. [Medline].
Wilkinson IM, Russell RW. Arteries of the head and neck in giant cell arteritis. A pathological study to show the pattern of arterial involvement. Arch Neurol. Nov 1972;27(5):378-91. [Medline].
Amor-Dorado JC, Llorca J, Garcia-Porrua C, Costa C, Perez-Fernandez N, Gonzalez-Gay MA. Audiovestibular manifestations in giant cell arteritis: a prospective study. Medicine (Baltimore). Jan 2003;82(1):13-26. [Medline].
Ellen H, Nusser J. Which clinical features and lab findings increase the likelihood of temporal arteritis?. The Journal of Family Practice. 2008;57:119-120.
Schmidt WA, Kraft HE, Vorpahl K, Völker L, Gromnica-Ihle EJ. Color duplex ultrasonography in the diagnosis of temporal arteritis. N Engl J Med. Nov 6 1997;337(19):1336-42. [Medline].
Salvarani C, Silingardi M, Ghirarduzzi A, et al. Is duplex ultrasonography useful for the diagnosis of giant-cell arteritis?. Ann Intern Med. Aug 20 2002;137(4):232-8. [Medline].
Alberts M, Mosen D. Diagnosing temporal arteritis: duplex vs biopsy. Quarterly Journal of Medicine. 2007;100:785-789.
Bley TA, Reinhard M, Hauenstein C, Markl M, Warnatz K, Hetzel A. Comparison of duplex sonography and high-resolution magnetic resonance imaging in the diagnosis of giant cell (temporal) arteritis. Arthritis Rheum. Aug 2008;58(8):2574-8. [Medline].
Marano SR, Fischer DW, Gaines C, Sonntag VK. Anatomical study of the superficial temporal artery. Neurosurgery. Jun 1985;16(6):786-90. [Medline].
Wolff K et al. Fig 243-4. In: Fitzpatrick's Dermatology In General Medicine. 7th. 2008:2291.
DAnesh-Meyer H, Eagle R, Kubis K, Savineo P, and Sergott R. Low Diagnositc Yield with Second Biopsies in Suspected Giant Cell Arteritis. Journal of Neuro-Opthalmology. 2000;20:213-215.
Levin L, Nuiederkohr R. A Bayesian Analysis of the True Sensitivity of a Temporal Artery Biopsy. Investigative Opthalmology & Visual Science. 2007;48:675-680.
Armstrong AT, Tyler WB, Wood GC, Harrington TM. Clinical importance of the presence of giant cells in temporal arteritis. J Clin Pathol. May 2008;61(5):669-71. [Medline].
Martinez-Taboada VM, Rodriguez-Valverde V, Carreno L, Lopez-Longo J, Figueroa M, Belzunegui J. A double-blind placebo controlled trial of etanercept in patients with giant cell arteritis and corticosteroid side effects. Ann Rheum Dis. May 2008;67(5):625-30. [Medline].
Cuizhen K, Scula C. Mesenteric Involvement in Giant Cell Arteritis. An Underrecognized Complication?: Analysis of a Case Series with Clinicoanatomic Correlation. Medicine. 2008;87:45-51.
Albert DM, Searl SS, Craft JL. Histologic and ultrastructural characteristics of temporal arteritis. The value of the temporal artery biopsy. Ophthalmology. Oct 1982;89(10):1111-26. [Medline].
Albertini JG, Ramsey ML, Marks VJ. Temporal artery biopsy in a dermatologic surgery practice. Dermatol Surg. Jun 1999;25(6):501-8. [Medline].
Bevan AT, Dunnill MS, Harrison MJ. Clinical and biopsy findings in temporal arteritis. Ann Rheum Dis. May 1968;27(3):271-7. [Medline].
Birkhead NC, Wagener HP, Shick RM. Treatment of temporal arteritis with adrenal corticosteroids; results in fifty-five cases in which lesion was proved at biopsy. J Am Med Assoc. Mar 9 1957;163(10):821-7. [Medline].
Brennan J, McCrary JA 3rd. Diagnosis of superficial temporal arteritis. Ann Ophthalmol. Aug 1975;7(8):1125-9. [Medline].
Chmelewski WL, McKnight KM, Agudelo CA, Wise CM. Presenting features and outcomes in patients undergoing temporal artery biopsy. A review of 98 patients. Arch Intern Med. Aug 1992;152(8):1690-5. [Medline].
Fauchald P, Rygvold O, Oystese B. Temporal arteritis and polymyalgia rheumatica. Clinical and biopsy findings. Ann Intern Med. Dec 1972;77(6):845-52. [Medline].
Fernandez-Herlihy L. Temporal arteritis: clinical aids to diagnosis. J Rheumatol. Dec 1988;15(12):1797-801. [Medline].
Hall S, Persellin S, Lie JT, O'Brien PC, Kurland LT, Hunder GG. The therapeutic impact of temporal artery biopsy. Lancet. Nov 26 1983;2(8361):1217-20. [Medline].
Hedges TR 3rd, Gieger GL, Albert DM. The clinical value of negative temporal artery biopsy specimens. Arch Ophthalmol. Aug 1983;101(8):1251-4. [Medline].
Huston KA, Hunder GG, Lie JT, Kennedy RH, Elveback LR. Temporal arteritis: a 25-year epidemiologic, clinical, and pathologic study. Ann Intern Med. Feb 1978;88(2):162-7. [Medline].
Kelley JS. Doppler ultrasound flow detector used in temporal artery biopsy. Arch Ophthalmol. May 1978;96(5):845-6. [Medline].
Kent RB 3rd, Thomas L. Temporal artery biopsy. Am Surg. Jan 1990;56(1):16-21. [Medline].
Klein RG, Campbell RJ, Hunder GG, Carney JA. Skip lesions in temporal arteritis. Mayo Clin Proc. Aug 1976;51(8):504-10. [Medline].
Lam BL, Wirthlin RS, Gonzalez A, Dubovy SR, Feuer WJ. Giant cell arteritis among Hispanic Americans. Am J Ophthalmol. Jan 2007;143(1):161-3. [Medline].
Levine SM, Hellmann DB. Giant cell arteritis. Curr Opin Rheumatol. Jan 2002;14(1):3-10. [Medline].
Nordborg E, Nordborg C. Giant cell arteritis: epidemiological clues to its pathogenesis and an update on its treatment. Rheumatology (Oxford). Mar 2003;42(3):413-21. [Medline].
Nordborg E, Nordborg C. Giant cell arteritis: strategies in diagnosis and treatment. Curr Opin Rheumatol. Jan 2004;16(1):25-30. [Medline].
Schumacher HR, Klippel JH, Koopman WJ, eds. Vasculitis. In: Primer on the Rheumatic Diseases. 10th ed. Atlanta, Ga: Arthritis Foundation; 1993:136-48.
Seko Y. Giant cell and Takayasu arteritis. Curr Opin Rheumatol. Jan 2007;19(1):39-43. [Medline].
Sorensen S, Lorenzen I. Giant-cell arteritis, temporal arteritis and polymyalgia rheumatica. A retrospective study of 63 patients. Acta Med Scand. 1977;201(3):207-13. [Medline].
Weyand CM, Bartley GB. Giant cell arteritis: new concepts in pathogenesis and implications for management. Am J Ophthalmol. Mar 1997;123(3):392-5. [Medline].
Further Reading
Keywords
temporal arteritis, giant cell arteritis, arteritis temporalis, arteritis cranialis, Horton disease, Horton's disease, granulomatous arteritis, arteritis of the aged, cranial arteritis, systemic vasculitis, TA, giant cell arteritis, temporal arteritis
Follow-up: Temporal (Giant Cell) Arteritis