eMedicine Specialties > Dermatology > Environmental

Friction Blisters

Author: Robert A Schwartz, MD, MPH, Professor and Head of Dermatology, Professor of Medicine, Professor of Pediatrics, Professor of Pathology, Professor of Preventive Medicine and Community Health, UMDNJ-New Jersey Medical School
Coauthor(s): Kuljit Chima, MD, Fellow, Departments of Dermatology and Pathology, University of Medicine and Dentistry of New Jersey; W Clark Lambert, MD, PhD, Professor and Head, Dermatopathology, Departments of Pathology and Dermatology, UMDNJ-New Jersey Medical School
Contributor Information and Disclosures

Updated: Apr 30, 2008

Introduction

Background

Friction blisters of the skin commonly occur in active populations. They are the result of frictional forces between the involved skin area and the object with which the skin is in contact. Friction blisters create localized discomfort; however, they should not be taken lightly because secondary impetigo may become a serious complication with resulting cellulitis and sepsis.1

The bulk of research on friction blisters comes from the military because of the nature of the physical activity involved in this field. Friction blisters have also received much attention in the field of sports medicine.

The eMedicine articles Impetigo and Cellulitis may be helpful, as may the Medscape Exercise and Sports Medicine Resource Center and the Sepsis Resource Center.

Pathophysiology

A frictional force causing friction blisters occurs when the skin is in contact with a surface and an attempt is made to move across the skin with an external force. Frictional force opposes this movement. The influence of epidermal hydration on the friction of human skin against textiles was studied. Increasing cutaneous hydration may cause sex-specific changes in the mechanical properties and/or surface topography of human skin, leading to skin softening and increased real contact area and adhesion.2

Studies involving rubbing the skin with a constant force show an initial slight exfoliation of the skin over the involved area. Focally, mild erythema also develops. The patient may experience stinging or burning, while a zone of pallor develops around the erythematous area. The pallor eventually extends into the region of erythema and this area develops into a blister.

The effect of wearing socks with different frictional properties on plantar shear was studied because this is a possible mechanical risk factor for foot lesion development.3 Wearing socks with low friction against the foot skin reduced the plantar shear force on the skin more than a sock with low friction against the insole.

Mortality/Morbidity

Secondary impetigo may become a serious complication, with the potential for cellulitis and sepsis.

Race

No known predilection is reported for any particular race.

Sex

No known predilection is described for either sex.

Age

No known predilection is apparent for any age group.

Clinical

History

  • Children often present with poorly fitting shoes and reporting a blister on the heel.
  • Friction blisters tend to occur in areas of thick adherent stratum corneum (eg, palms, soles, heels, dorsa of fingers).
  • In regions of the body where the stratum corneum is thinner, a repeated friction force causes the stratum corneum to erode, and instead of a blister, an erosion or abrasion occurs.
  • The likelihood of forming a friction blister at susceptible sites is based on the magnitude of the frictional force and the number of times an object moves across the skin (ie, shear cycles). Moisture and lubricating substances present on the skin surface are additional factors.
  • With a greater frictional force, fewer cycles of rubbing against the skin are needed to produce a blister.
  • Moisture on the skin surface may either increase the friction force or, in the case of very moist skin, decrease it temporarily by providing lubrication.
  • Lubricating agents also tend to reduce the friction force temporarily at the onset; however, friction tends to increase with prolonged application of the external force.
  • Pyogenic granuloma on the hand has been described subsequent to a friction blister in a hand surgeon.4

Physical

Discrete bullae formation at sites of trauma is evident.

Causes

Poorly fitting shoes are the most common cause. Heat, sweating, and maceration of the skin may predispose to friction blister formation.

More on Friction Blisters

Overview: Friction Blisters
Differential Diagnoses & Workup: Friction Blisters
Treatment & Medication: Friction Blisters
Follow-up: Friction Blisters
References
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References

  1. Hoeffler DF. Friction blisters and cellulitis in a navy recruit population. Mil Med. May 1975;140(5):333-7. [Medline].

  2. Gerhardt LC, Strässle V, Lenz A, Spencer ND, Derler S. Influence of epidermal hydration on the friction of human skin against textiles. J R Soc Interface. Mar 10 2008;[Medline].

  3. Dai XQ, Li Y, Zhang M, Cheung JT. Effect of sock on biomechanical responses of foot during walking. Clin Biomech (Bristol, Avon). Mar 2006;21(3):314-21. [Medline].

  4. Sasmaz S, Karaoguz A, Uzel M, Coban YK. Pyogenic granuloma on the hand subsequent to friction blister in a hand surgeon. Dermatol Online J. 2006;12(3):22. [Medline].

  5. Sevilla JA, Rodriguez FM, Dallasta RM. [The treatment of blisters caused by friction while hiking the Road to Santiago]. Rev Enferm. Jan 2007;30(1):32-6. [Medline].

  6. Knapik JJ, Reynolds K, Barson J. Influence of an antiperspirant on foot blister incidence during cross-country hiking. J Am Acad Dermatol. Aug 1998;39(2 Pt 1):202-6. [Medline].

  7. Reynolds K, Darrigrand A, Roberts D, Knapik J, Pollard J, Duplantis K, et al. Effects of an antiperspirant with emollients on foot-sweat accumulation and blister formation while walking in the heat. J Am Acad Dermatol. Oct 1995;33(4):626-30. [Medline].

  8. Jagoda A, Madden H, Hinson C. A friction blister prevention study in a population of marines. Mil Med. Jan 1981;146(1):42-4. [Medline].

  9. Knapik JJ, Hamlet MP, Thompson KJ, Jones BH. Influence of boot-sock systems on frequency and severity of foot blisters. Mil Med. Oct 1996;161(10):594-8. [Medline].

  10. Smith W, Walter J Jr, Bailey M. Effects of insoles in Coast Guard basic training footwear. J Am Podiatr Med Assoc. Dec 1985;75(12):644-7. [Medline].

  11. Spence WR, Shields MN. Insole to reduce shearing forces on the soles of the feet. Arch Phys Med Rehabil. Aug 1968;49(8):476-9. [Medline].

  12. Spence WR, Shields MN. New insole for prevention of athletic blisters. J Sports Med Phys Fitness. Sep 1968;8(3):177-80. [Medline].

  13. Akers WA. Measurements of friction injuries in man. Am J Ind Med. 1985;8(4-5):473-81. [Medline].

  14. Akers WA, Leonard F, Ousterhout DK, Cortese TA Jr. Treating friction blisters with alkyl- -cyanoacrylates. Arch Dermatol. Apr 1973;107(4):544-7. [Medline].

  15. Akers WA, Sulzberger MB. The friction blister. Mil Med. Jan 1972;137(1):1-7. [Medline].

  16. Darrigrand A, Reynolds K, Jackson R, Hamlet M, Roberts D. Efficacy of antiperspirants on feet. Mil Med. May 1992;157(5):256-9. [Medline].

  17. Epstein WL, Fukuyama K, Cortese TA. Autoradiographic study of friction blisters. RNA, DNA, and protein synthesis. Arch Dermatol. Jan 1969;99(1):94-106. [Medline].

  18. Herring KM, Richie DH Jr. Friction blisters and sock fiber composition. A double-blind study. J Am Podiatr Med Assoc. Feb 1990;80(2):63-71. [Medline].

  19. Hunter JA, McVittie E, Comaish JS. Light and electron microscopic studies of physical injury to the skin. II. Friction. Br J Dermatol. May 1974;90(5):491-9. [Medline].

  20. Knapik JJ, Reynolds KL, Duplantis KL, Jones BH. Friction blisters. Pathophysiology, prevention and treatment. Sports Med. Sep 1995;20(3):136-47. [Medline].

  21. Rumball JS, Lebrun CM, Di Ciacca SR, Orlando K. Rowing injuries. Sports Med. 2005;35(6):537-55. [Medline].

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Further Reading

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Keywords

cellulitis, sepsis, impetigo, moleskin

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Contributor Information and Disclosures

Author

Robert A Schwartz, MD, MPH, Professor and Head of Dermatology, Professor of Medicine, Professor of Pediatrics, Professor of Pathology, Professor of Preventive Medicine and Community Health, UMDNJ-New Jersey Medical School
Robert A Schwartz, MD, MPH is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American College of Physicians, and Sigma Xi
Disclosure: Nothing to disclose.

Coauthor(s)

Kuljit Chima, MD, Fellow, Departments of Dermatology and Pathology, University of Medicine and Dentistry of New Jersey
Kuljit Chima, MD is a member of the following medical societies: American Academy of Dermatology
Disclosure: Nothing to disclose.

W Clark Lambert, MD, PhD, Professor and Head, Dermatopathology, Departments of Pathology and Dermatology, UMDNJ-New Jersey Medical School
W Clark Lambert, MD, PhD is a member of the following medical societies: American Academy of Dermatology, American College of Physicians, American Dermatological Association, American Society of Dermatopathology, International Academy of Pathology, Medical Society of New Jersey, Sigma Xi, and Society for Investigative Dermatology
Disclosure: Nothing to disclose.

Medical Editor

Robin Travers, MD, Professor, Department of Dermatology, Boston University School of Medicine
Disclosure: Nothing to disclose.

Pharmacy Editor

Michael J Wells, MD, Associate Professor, Department of Dermatology, Texas Tech University Health Sciences Center
Michael J Wells, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, and Texas Medical Association
Disclosure: Nothing to disclose.

Managing Editor

Jeffrey Meffert, MD, Assistant Clinical Professor of Dermatology, University of Texas Health Science Center-San Antonio
Jeffrey Meffert, MD is a member of the following medical societies: American Academy of Dermatology, American Medical Association, Association of Military Dermatologists, and Texas Dermatological Society
Disclosure: Nothing to disclose.

CME Editor

Catherine Quirk, MD, Clinical Assistant Professor, Department of Dermatology, Brown University
Catherine Quirk, MD is a member of the following medical societies: Alpha Omega Alpha and American Academy of Dermatology
Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD, Director, Department of Dermatology, Geisinger Medical Center
Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology
Disclosure: Nothing to disclose.

 
 
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