Dermatologic Aspects of Actinomycosis Differential Diagnoses

  • Author: Talib Najjar, DMD, MDS, PhD; Chief Editor: Dirk M Elston, MD   more...
 
Updated: May 23, 2012
 
 

Differential Diagnoses

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Contributor Information and Disclosures
Author

Talib Najjar, DMD, MDS, PhD  Professor of Oral and Maxillofacial Surgery and Pathology, University of Medicine and Dentistry of New Jersey

Talib Najjar, DMD, MDS, PhD is a member of the following medical societies: American Society for Clinical Pathology

Disclosure: Nothing to disclose.

Specialty Editor Board

Janet Fairley, MD  Professor and Head, Department of Dermatology, University of Iowa, Roy J and Lucille A Carver College of Medicine

Janet Fairley, MD is a member of the following medical societies: American Academy of Dermatology, American Dermatological Association, American Federation for Medical Research, and Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Michael J Wells, MD  Associate Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine

Michael J Wells, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, and Texas Medical Association

Disclosure: Nothing to disclose.

Drore Eisen, MD, DDS  Consulting Staff, Department of Dermatology, Dermatology Research Associates of Cincinnati

Drore Eisen, MD, DDS is a member of the following medical societies: American Academy of Dermatology, American Academy of Oral Medicine, and American Dental Association

Disclosure: Nothing to disclose.

Catherine M Quirk, MD  Clinical Assistant Professor, Department of Dermatology, University of Pennsylvania

Catherine M Quirk, MD is a member of the following medical societies: Alpha Omega Alpha and American Academy of Dermatology

Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD  Director, Ackerman Academy of Dermatopathology, New York

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Additional Contributors

Many thanks for continuous help and advice from doctor Edward Jonson, MD, internationally known infectious diseases specialist and Dean, Trinity School of Medicine and Caribbean Studies, Saint Vincent.

References

  1. Schaal KP, Schofield GM. Classification and identification of clinically significant Actinomycetaceae. In: Ortiz-Ortiz L, Bojalil LF, Yakoleff V, eds. Biological, Biochemical, and Biomedical Aspects of Actinomycetes. Orlando, Fla: Academic Press; 1984:505-20.

  2. Eastridge CE, Prather JR, Hughes FA Jr, Young JM, McCaughan JJ Jr. Actinomycosis: a 24 year experience. South Med J. Jul 1972;65(7):839-43. [Medline].

  3. Richtsmeier WJ, Johns ME. Actinomycosis of the head and neck. CRC Crit Rev Clin Lab Sci. Nov 1979;11(2):175-202. [Medline].

  4. Erikson D. Pathogenic anaerobic organisms of the Actinomyces group. Br Med Res Council Special Report Series. 1940;240:1.

  5. Waksman SA, Henrici AT. The Nomenclature and Classification of the Actinomycetes. J Bacteriol. Oct 1943;46(4):337-41. [Medline].

  6. Georg LK. The agents of human actinomycosis. In: Balows A, Dehau RM, Dowell VR, eds. Anaerobic Bacteria: Role in Disease. Springfield, Ill: Charles C Thomas; 1974:237-56.

  7. Brock DW, Georg LK, Brown JM, Hicklin MD. Actinomycosis caused by Arachnia propionica: report of 11 cases. Am J Clin Pathol. Jan 1973;59(1):66-77. [Medline].

  8. Behbehani MJ, Heeley JD, Jordan HV. Comparative histopathology of lesions produced by Actinomyces israelii, Actinomyces naeslundii, and Actinomyces viscosus in mice. Am J Pathol. Mar 1983;110(3):267-74. [Medline].

  9. Najjar TA, McKeon J, Smith L, Parson R. Septic arthritis of TMJ secondary to experimental osteosynthesis. J Dent Res. 1980;59A:306.

  10. Weese WC, Smith IM. A study of 57 cases of actinomycosis over a 36-year period. A diagnostic 'failure' with good prognosis after treatment. Arch Intern Med. Dec 1975;135(12):1562-8. [Medline].

  11. Bennhoff DF. Actinomycosis: diagnostic and therapeutic considerations and a review of 32 cases. Laryngoscope. Sep 1984;94(9):1198-217. [Medline].

  12. Coleman RM, Georg LK, Rozzell AR. Actinomyces naeslundii as an agent of human actinomycosis. Appl Microbiol. Sep 1969;18(3):420-6. [Medline].

  13. Eng RH, Corrado ML, Cleri D, Cherubin C, Goldstein EJ. Infections caused by Actinomyces viscosus. Am J Clin Pathol. Jan 1981;75(1):113-6. [Medline].

  14. Pine L, Overman JR. Determination of the structure and composition of the "sulphur granules" of Actinomyces bovis. J Gen Microbiol. Aug 1963;32:209-23. [Medline].

  15. Brown JR. Human actinomycosis. A study of 181 subjects. Hum Pathol. Sep 1973;4(3):319-30. [Medline].

  16. Lewis RP, Sutter VL, Finegold SM. Bone infections involving anaerobic bacteria. Medicine (Baltimore). Jul 1978;57(4):279-305. [Medline].

  17. Peloux Y, Raoult D, Chardon H, Escarguel JP. Actinomyces odontolyticus infections: review of six patients. J Infect. Sep 1985;11(2):125-9. [Medline].

  18. Metgud SC. Primary cutaneous actinomycosis: a rare soft tissue infection. Indian J Med Microbiol. Apr-Jun 2008;26(2):184-6. [Medline].

  19. Schaal KP, Beaman BL. Clinical significance of actinomycetes. In: Goodfellow M, Mordarski M, Williams S, eds. The Biology of the Actinomycetes. New York: Academic Press; 1983:389-424.

  20. Hennrikus EF, Pederson L. Disseminated actinomycosis. West J Med. Aug 1987;147(2):201-4. [Medline].

  21. Lerner PI. Susceptibility of pathogenic actinomycetes to antimicrobial compounds. Antimicrob Agents Chemother. Mar 1974;5(3):302-9. [Medline].

  22. Deshpande RB, Rao AA. Cervicofacial actinomycosis with upper cervical vertebral involvement and fatal meningitis (a case report). J Postgrad Med. Oct 1985;31(4):223-5. [Medline].

  23. Holmberg K, Nord CE, Dornbusch K. Antimicrobial in vitro susceptibility of actinomyces israelii and arachnia propionica. Scand J Infect Dis. 1977;9(1):40-5. [Medline].

  24. Boand A, Novak M. Sensitivity changes of Actinomyces bovis to penicillin and streptomycin. J Bacteriol. May 1949;57(5):501-8. [Medline].

  25. Edelmann M, Cullmann W, Nowak KH, Kozuschek W. Treatment of abdominothoracic actinomycosis with imipenem. Eur J Clin Microbiol. Apr 1987;6(2):194-5. [Medline].

  26. Abdalla J, Myers J, Moorman J. Actinomycotic infection of the oesophagus. J Infect. Aug 2005;51(2):E39-43. [Medline].

  27. Al-Hezaimi K. Apical actinomycosis: case report. J Can Dent Assoc. 2010;76:a113. [Medline].

  28. Allen MR, Burr DB. The pathogenesis of bisphosphonate-related osteonecrosis of the jaw: so many hypotheses, so few data. J Oral Maxillofac Surg. May 2009;67(5 Suppl):61-70. [Medline].

  29. Aydin A, Erkiliç S, Bayazit YA, Koçer NE, Ozer E, Kanlikama M. Relation between actinomycosis and histopathological and clinical features of the palatine tonsils: a comparative study between adult and pediatric patients. Rev Laryngol Otol Rhinol (Bord). 2005;126(2):95-8. [Medline].

  30. Carrillo M, Valdez B, Vargas L, Alvarez L, Schorr M, Zlatev R, et al. In vitro Actinomyces israelii biofilm development on IUD copper surfaces. Contraception. Mar 2010;81(3):261-4. [Medline].

  31. Crossman T, Herold J. Actinomycosis of the maxilla - a case report of a rare oral infection presenting in general dental practice. Br Dent J. Feb 28 2009;206(4):201-2. [Medline].

  32. Göçmen G, Varol A, Göker K, Basa S. Actinomycosis: report of a case with a persistent extraoral sinus tract. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. Dec 2011;112(6):e121-3. [Medline].

  33. Hemalata M, Prasad S, Venkatesh K, Niveditha SR, Kumar SA. Cytological diagnosis of actinomycosis and eumycetoma: A report of two cases. Diagn Cytopathol. Mar 18 2010;[Medline].

  34. Katanic N, Pavlovic M, Bojovic K, Dulovic O, Gvozdenovic E, Simonovic J. [Therapeutic approach to actinomycosis--experience gained at the department of infectious and tropical diseases]. Med Pregl. Mar-Apr 2011;64(3-4):207-10. [Medline].

  35. Kim TS, Han J, Koh WJ, Choi JC, Chung MJ, Lee JH, et al. Thoracic actinomycosis: CT features with histopathologic correlation. AJR Am J Roentgenol. Jan 2006;186(1):225-31. [Medline].

  36. Kimura H. [Cervical actinomycosis due to Actinomyces naeslundii]. Nihon Jibiinkoka Gakkai Kaiho. Jul 2011;114(7):620-3. [Medline].

  37. Kurtaran H, Ugur KS, Ark N, Vuran O, Gunduz M. Tongue abscess with actinomycosis. J Craniofac Surg. May 2011;22(3):1107-9. [Medline].

  38. Maier H, Tisch M. [Bacterial sialadenitis]. HNO. Mar 2010;58(3):229-36. [Medline].

  39. Mamais C, Dias A, Walker J, Vydianath SR. Parotid actinomycosis mimicking metastatic lymphadenopathy. West Indian Med J. Jun 2011;60(3):349-50. [Medline].

  40. Ozaras R, Mert A. Clinical image: primary actinomycosis of the hand. Arthritis Rheum. Feb 2010;62(2):419. [Medline].

  41. Pignataro L, Torretta S, Capaccio P, Esposito S, Marchisio P. Unusual otolaryngological manifestations of certain systemic bacterial and fungal infections in children. Int J Pediatr Otorhinolaryngol. Dec 2009;73 Suppl 1:S33-7. [Medline].

  42. Rothschild B, Naples V, Barbian L. Bone manifestations of actinomycosis. Ann Diagn Pathol. Feb 2006;10(1):24-7. [Medline].

  43. Schumann R, Lorenz KJ, Tisch M, Maier H. [Laryngeal and pharyngeal actinomycosis]. HNO. Aug 2010;58(8):867-71. [Medline].

  44. Smith MH, Harms PW, Newton DW, Lebar B, Edwards SP, Aronoff DM. Mandibular Actinomyces osteomyelitis complicating florid cemento-osseous dysplasia: case report. BMC Oral Health. Jul 21 2011;11:21. [Medline]. [Full Text].

  45. Soler Sendra A, Subirana Pozo FX, Consola Maroto B, Serra Carreras J, Cuquet Pedragosa J. [Tonsillar actinomycosis manifested as expectorated debris]. Acta Otorrinolaringol Esp. Sep-Oct 2009;60(5):372-4. [Medline].

  46. Wong VK, Turmezei TD, Weston VC. Actinomycosis. BMJ. Oct 11 2011;343:d6099. [Medline].

 
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Photomicrograph of gram-positive organisms in actinomycosis, which may be confused with those causing a mycotic infection (hematoxylin and eosin, original magnification X40).
Photomicrograph of a characteristic sulfur granule of actinomycosis (hematoxylin and eosin, original magnification X10).
Diagram of potential oral anaerobic infection.
Image shows an oral fistula caused by actinomycosis.
Periapical radiograph shows infection in the premolar tooth.
 
 
 
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