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Dermatologic Manifestations of Gastrointestinal Disease: Multimedia

Author: Christine J Ko, MD, Assistant Professor, Departments of Dermatology and Pathology, Yale University School of Medicine
Contributor Information and Disclosures

Updated: Jan 23, 2009

Multimedia

Oral Kaposi sarcoma in a patient with AIDS. Note ...Media file 1: Oral Kaposi sarcoma in a patient with AIDS. Note the characteristic purple hemorrhagic papules coalescing into an irregular plaque.
Oral Kaposi sarcoma in a patient with AIDS. Note ...

Oral Kaposi sarcoma in a patient with AIDS. Note the characteristic purple hemorrhagic papules coalescing into an irregular plaque.

Multiple large intestinal polyps in a patient wit...Media file 2: Multiple large intestinal polyps in a patient with Gardner syndrome. Courtesy of Christina Surawicz, MD, Harborview Medical Center, Seattle, Wash.
Multiple large intestinal polyps in a patient wit...

Multiple large intestinal polyps in a patient with Gardner syndrome. Courtesy of Christina Surawicz, MD, Harborview Medical Center, Seattle, Wash.

Pyoderma gangrenosum. Note the rolled-up, edemato...Media file 3: Pyoderma gangrenosum. Note the rolled-up, edematous, and undermined border with the surrounding halo of bright-red erythema. The base of the ulcer contains a fibrinopurulent exudate. This ulcer evolved from a "pimple" over a period of just a few weeks.
Pyoderma gangrenosum. Note the rolled-up, edemato...

Pyoderma gangrenosum. Note the rolled-up, edematous, and undermined border with the surrounding halo of bright-red erythema. The base of the ulcer contains a fibrinopurulent exudate. This ulcer evolved from a "pimple" over a period of just a few weeks.

Koilonychia. Note the double concavity (longitudi...Media file 4: Koilonychia. Note the double concavity (longitudinal and transverse) of the nails.
Koilonychia. Note the double concavity (longitudi...

Koilonychia. Note the double concavity (longitudinal and transverse) of the nails.

Scleroderma affecting the hands. Note the taut ap...Media file 5: Scleroderma affecting the hands. Note the taut appearance of the skin and the curved nails.
Scleroderma affecting the hands. Note the taut ap...

Scleroderma affecting the hands. Note the taut appearance of the skin and the curved nails.

Acanthosis nigricans (AN) in a patient with pancr...Media file 6: Acanthosis nigricans (AN) in a patient with pancreatic cancer. Note the papillomatous appearance of the axillary skin. This patient had previously been diagnosed with typical AN related to diabetes mellitus. After a long period of stability, the AN became much more severe and involved other parts of his skin, including the eyelids and scalp, prompting the search for malignancy.
Acanthosis nigricans (AN) in a patient with pancr...

Acanthosis nigricans (AN) in a patient with pancreatic cancer. Note the papillomatous appearance of the axillary skin. This patient had previously been diagnosed with typical AN related to diabetes mellitus. After a long period of stability, the AN became much more severe and involved other parts of his skin, including the eyelids and scalp, prompting the search for malignancy.

Sister Mary Joseph nodule in a patient with gastr...Media file 7: Sister Mary Joseph nodule in a patient with gastric carcinoma. Note the shiny, reddish, telangiectatic group of papules in the umbilicus.
Sister Mary Joseph nodule in a patient with gastr...

Sister Mary Joseph nodule in a patient with gastric carcinoma. Note the shiny, reddish, telangiectatic group of papules in the umbilicus.

Arteriovenous malformations as seen on CT scan in...Media file 8: Arteriovenous malformations as seen on CT scan in a patient with Osler-Weber-Rendu syndrome. The patches of hyperdensity within the liver are the result of previous embolization procedures.
Arteriovenous malformations as seen on CT scan in...

Arteriovenous malformations as seen on CT scan in a patient with Osler-Weber-Rendu syndrome. The patches of hyperdensity within the liver are the result of previous embolization procedures.

Telangiectases in the gastric mucosa of a patient...Media file 9: Telangiectases in the gastric mucosa of a patient with Osler-Weber-Rendu syndrome. The lesions can be seen most prominently at the 2-o'clock position proximally and the 3-o'clock position distally. Note the prominent red color of the lesions. Although these particular lesions appear flat, some GI telangiectasias may be slightly elevated. Reprinted with permission from Gastrointestinal Endoscopy, Second edition, Gower Medical Publishing, New York, 1991.
Telangiectases in the gastric mucosa of a patient...

Telangiectases in the gastric mucosa of a patient with Osler-Weber-Rendu syndrome. The lesions can be seen most prominently at the 2-o'clock position proximally and the 3-o'clock position distally. Note the prominent red color of the lesions. Although these particular lesions appear flat, some GI telangiectasias may be slightly elevated. Reprinted with permission from Gastrointestinal Endoscopy, Second edition, Gower Medical Publishing, New York, 1991.

Postcricoid web in a patient with Plummer-Vinson ...Media file 10: Postcricoid web in a patient with Plummer-Vinson syndrome. Note the 2 small openings within the web at the 2- and 6-o'clock positions, representing a significantly compromised proximal esophageal lumen. Reprinted with permission from Gastrointestinal Endoscopy, Second edition, Gower Medical Publishing, New York, 1991.
Postcricoid web in a patient with Plummer-Vinson ...

Postcricoid web in a patient with Plummer-Vinson syndrome. Note the 2 small openings within the web at the 2- and 6-o'clock positions, representing a significantly compromised proximal esophageal lumen. Reprinted with permission from Gastrointestinal Endoscopy, Second edition, Gower Medical Publishing, New York, 1991.

Patient with porphyria cutanea tarda.Media file 11: Patient with porphyria cutanea tarda.
Patient with porphyria cutanea tarda.

Patient with porphyria cutanea tarda.

Patient with dermatitis herpetiformis; often thes...Media file 12: Patient with dermatitis herpetiformis; often these patients are afflicted with celiac sprue.
Patient with dermatitis herpetiformis; often thes...

Patient with dermatitis herpetiformis; often these patients are afflicted with celiac sprue.

The lacy, white reticulated lesions in this patie...Media file 13: The lacy, white reticulated lesions in this patient are consistent with lichen planus.
The lacy, white reticulated lesions in this patie...

The lacy, white reticulated lesions in this patient are consistent with lichen planus.

More on Dermatologic Manifestations of Gastrointestinal Disease

References

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Further Reading

Keywords

Kaposi sarcoma, Plummer-Vinson syndrome, Patterson-Brown-Kelly syndrome, epidermolysis bullosa, EB, scleroderma, systemic sclerosis, pemphigus vulgaris, PV, acanthosis nigricans, Sister Mary Joseph nodule, Osler-Weber-Rendu syndrome, hereditary hemorrhagic telangiectasia, hemochromatosis, porphyria cutanea tarda, PCT, pancreatic fat necrosis, lichen planus, Peutz-Jeghers syndrome, PJS, Henoch-Schönlein purpura, dermatitis herpetiformis, DH, blue rubber bleb nevus syndrome, familial adenomatous polyposis, Gardner syndrome, Muir-Torre syndrome, MTS, Cowden disease, multiple hamartoma syndrome, Cronkhite-Canada syndrome, inflammatory bowel disease, Crohn disease, Crohn's disease, CD, ulcerative colitis, UC

Contributor Information and Disclosures

Author

Christine J Ko, MD, Assistant Professor, Departments of Dermatology and Pathology, Yale University School of Medicine
Christine J Ko, MD is a member of the following medical societies: American Academy of Dermatology, American Society of Dermatopathology, and International Society of Dermatopathology
Disclosure: Nothing to disclose.

Medical Editor

Robin Travers, MD, Assistant Professor of Medicine (Dermatology), Dartmouth University School of Medicine; Staff Dermatologist, New England Baptist Hospital; Private Practice, SkinCare Physicians
Robin Travers, MD is a member of the following medical societies: American Academy of Dermatology, American Medical Informatics Association, Massachusetts Medical Society, Medical Dermatology Society, and Women's Dermatologic Society
Disclosure: Nothing to disclose.

Pharmacy Editor

Richard P Vinson, MD, Assistant Clinical Professor, Department of Dermatology, Texas Tech University School of Medicine; Consulting Staff, Mountain View Dermatology, PA
Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Association of Military Dermatologists, Texas Dermatological Society, and Texas Medical Association
Disclosure: Nothing to disclose.

Managing Editor

Christen M Mowad, MD, Associate Professor, Department of Dermatology, Geisinger Medical Center
Christen M Mowad, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, and Phi Beta Kappa
Disclosure: Nothing to disclose.

CME Editor

Catherine Quirk, MD, Clinical Assistant Professor, Department of Dermatology, Brown University
Catherine Quirk, MD is a member of the following medical societies: Alpha Omega Alpha and American Academy of Dermatology
Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD, Director, Department of Dermatology, Geisinger Medical Center
Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology
Disclosure: Nothing to disclose.

 
 
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