eMedicine Specialties > Dermatology > Internal Medicine

Dermatologic Manifestations of Neurologic Disease: Multimedia

Author: Heather Kiraly Orkwis, Philadelphia College of Osteopathic Medicine
Coauthor(s): Theresa Dressler Conologue, DO, FAAD, Physician, Department of Dermatology, Geisinger Medical Center; Jeffrey Meffert, MD, Assistant Clinical Professor of Dermatology, University of Texas Health Science Center-San Antonio
Contributor Information and Disclosures

Updated: May 13, 2009

Multimedia

Crowe sign, axillary freckling, in neurofibromato...Media file 1: Crowe sign, axillary freckling, in neurofibromatosis type I.
Crowe sign, axillary freckling, in neurofibromato...

Crowe sign, axillary freckling, in neurofibromatosis type I.

Lisch nodule, iris hamartomas, in a patient with ...Media file 2: Lisch nodule, iris hamartomas, in a patient with neurofibromatosis type 1.
Lisch nodule, iris hamartomas, in a patient with ...

Lisch nodule, iris hamartomas, in a patient with neurofibromatosis type 1.

Segmental neurofibromatosis.Media file 3: Segmental neurofibromatosis.
Segmental neurofibromatosis.

Segmental neurofibromatosis.

A large cutaneous neurofibroma.Media file 4: A large cutaneous neurofibroma.
A large cutaneous neurofibroma.

A large cutaneous neurofibroma.

A port-wine stain in a patient with Sturge-Weber ...Media file 5: A port-wine stain in a patient with Sturge-Weber syndrome.
A port-wine stain in a patient with Sturge-Weber ...

A port-wine stain in a patient with Sturge-Weber syndrome.

Osler-Weber-Rendu disease with sublingual telangi...Media file 6: Osler-Weber-Rendu disease with sublingual telangiectasias. Courtesy of Dirk M. Elston, MD.
Osler-Weber-Rendu disease with sublingual telangi...

Osler-Weber-Rendu disease with sublingual telangiectasias. Courtesy of Dirk M. Elston, MD.

Whirls and swirls of hyperpigmentation in an infa...Media file 7: Whirls and swirls of hyperpigmentation in an infant with incontinentia pigmenti. Courtesy of military teaching file.
Whirls and swirls of hyperpigmentation in an infa...

Whirls and swirls of hyperpigmentation in an infant with incontinentia pigmenti. Courtesy of military teaching file.

Fluorescence of urine in a patient with porphyria...Media file 8: Fluorescence of urine in a patient with porphyria. Note the pink-to-coral red fluorescence of urine compared to a control sample. Courtesy of Dirk M. Elston, MD.
Fluorescence of urine in a patient with porphyria...

Fluorescence of urine in a patient with porphyria. Note the pink-to-coral red fluorescence of urine compared to a control sample. Courtesy of Dirk M. Elston, MD.

Chronic scarring and milia on the dorsal aspect o...Media file 9: Chronic scarring and milia on the dorsal aspect of the fingers and hand in a porphyria patient. Courtesy of Dirk M. Elston, MD, and James H. Keeling, MD.
Chronic scarring and milia on the dorsal aspect o...

Chronic scarring and milia on the dorsal aspect of the fingers and hand in a porphyria patient. Courtesy of Dirk M. Elston, MD, and James H. Keeling, MD.

Angiofibromas on the chin in a patient with tuber...Media file 10: Angiofibromas on the chin in a patient with tuberous sclerosis. Courtesy of Dirk M. Elston, MD.
Angiofibromas on the chin in a patient with tuber...

Angiofibromas on the chin in a patient with tuberous sclerosis. Courtesy of Dirk M. Elston, MD.

A connective tissue nevus (Shagreen patch) in a p...Media file 11: A connective tissue nevus (Shagreen patch) in a patient with tuberous sclerosis. Courtesy of Dirk M. Elston, MD.
A connective tissue nevus (Shagreen patch) in a p...

A connective tissue nevus (Shagreen patch) in a patient with tuberous sclerosis. Courtesy of Dirk M. Elston, MD.

Koenen tumor in a patient with tuberous sclerosis...Media file 12: Koenen tumor in a patient with tuberous sclerosis. Courtesy of Dirk M. Elston, MD.
Koenen tumor in a patient with tuberous sclerosis...

Koenen tumor in a patient with tuberous sclerosis. Courtesy of Dirk M. Elston, MD.

Multiple 1- to 2-mm, flat, dark-brown lentigines ...Media file 13: Multiple 1- to 2-mm, flat, dark-brown lentigines in a patient with LEOPARD syndrome (also termed multiple lentigines syndrome).
Multiple 1- to 2-mm, flat, dark-brown lentigines ...

Multiple 1- to 2-mm, flat, dark-brown lentigines in a patient with LEOPARD syndrome (also termed multiple lentigines syndrome).

Bullous diabeticorum. Courtesy of military teachi...Media file 14: Bullous diabeticorum. Courtesy of military teaching file.
Bullous diabeticorum. Courtesy of military teachi...

Bullous diabeticorum. Courtesy of military teaching file.

Acanthosis nigricans. Courtesy of Dirk M. Elston,...Media file 15: Acanthosis nigricans. Courtesy of Dirk M. Elston, MD.
Acanthosis nigricans. Courtesy of Dirk M. Elston,...

Acanthosis nigricans. Courtesy of Dirk M. Elston, MD.

Necrobiosis lipoidica diabeticorum. Courtesy of D...Media file 16: Necrobiosis lipoidica diabeticorum. Courtesy of Dirk M. Elston, MD.
Necrobiosis lipoidica diabeticorum. Courtesy of D...

Necrobiosis lipoidica diabeticorum. Courtesy of Dirk M. Elston, MD.

Herpes varicella zoster in a dermatomal distribut...Media file 17: Herpes varicella zoster in a dermatomal distribution of the chest. Courtesy of Dirk M. Elston, MD.
Herpes varicella zoster in a dermatomal distribut...

Herpes varicella zoster in a dermatomal distribution of the chest. Courtesy of Dirk M. Elston, MD.

Tzanck smear of the base of a herpetic blister sh...Media file 18: Tzanck smear of the base of a herpetic blister showing multinucleated giant cells. Courtesy of Dirk M. Elston, MD.
Tzanck smear of the base of a herpetic blister sh...

Tzanck smear of the base of a herpetic blister showing multinucleated giant cells. Courtesy of Dirk M. Elston, MD.

Seborrheic dermatitis of the face. Courtesy of Di...Media file 19: Seborrheic dermatitis of the face. Courtesy of Dirk M. Elston, MD.
Seborrheic dermatitis of the face. Courtesy of Di...

Seborrheic dermatitis of the face. Courtesy of Dirk M. Elston, MD.

Casal necklace in a patient with pellagra.Media file 20: Casal necklace in a patient with pellagra.
Casal necklace in a patient with pellagra.

Casal necklace in a patient with pellagra.

The classic bull's-eye appearance of erythema chr...Media file 21: The classic bull's-eye appearance of erythema chronicum migrans. Courtesy of Dirk M. Elston, MD.
The classic bull's-eye appearance of erythema chr...

The classic bull's-eye appearance of erythema chronicum migrans. Courtesy of Dirk M. Elston, MD.

A transverse band of leukonychia termed Mees line...Media file 22: A transverse band of leukonychia termed Mees lines. Courtesy of Dirk M. Elston, MD.
A transverse band of leukonychia termed Mees line...

A transverse band of leukonychia termed Mees lines. Courtesy of Dirk M. Elston, MD.

Mottled, bluish, netlike discoloration in livedo ...Media file 23: Mottled, bluish, netlike discoloration in livedo reticularis. Courtesy of Dirk M. Elston, MD.
Mottled, bluish, netlike discoloration in livedo ...

Mottled, bluish, netlike discoloration in livedo reticularis. Courtesy of Dirk M. Elston, MD.

More on Dermatologic Manifestations of Neurologic Disease

References

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Further Reading

Keywords

neurocutaneous disorders, neurofibromatosis type 1, NF1, von Recklinghausen disease, neurofibromatosis type 2, NF2 central neurofibromatosis, bilateral acoustic neuroma, tuberous sclerosis, Bourneville syndrome, epiloia, nevoid basal cell carcinoma syndrome, Gorlin syndrome, variegate porphyria, LEOPARD syndrome, multiple lentigines syndrome, ataxia-telangiectasia, AT, Louis-Bar syndrome, Sjögren-Larsson syndrome, SLS, incontinentia pigmenti, IP, Bloch-Sulzberger syndrome, Sturge-Weber syndrome, pellagra, varicella zoster virus, antiphospholipid syndrome, Sneddon syndrome, diabetes mellitus, lyme disease, arsenic poisoning, reflex sympathetic dystrophy, RSD, seborrheic dermatitis

Contributor Information and Disclosures

Author

Heather Kiraly Orkwis, Philadelphia College of Osteopathic Medicine
Heather Kiraly Orkwis is a member of the following medical societies: Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Coauthor(s)

Theresa Dressler Conologue, DO, FAAD, Physician, Department of Dermatology, Geisinger Medical Center
Theresa Dressler Conologue, DO, FAAD is a member of the following medical societies: American Academy of Cosmetic Surgery, American Academy of Dermatology, and American Society for Laser Medicine and Surgery
Disclosure: Nothing to disclose.

Jeffrey Meffert, MD, Assistant Clinical Professor of Dermatology, University of Texas Health Science Center-San Antonio
Jeffrey Meffert, MD is a member of the following medical societies: American Academy of Dermatology, American Medical Association, Association of Military Dermatologists, and Texas Dermatological Society
Disclosure: Nothing to disclose.

Medical Editor

Donald Belsito, MD, Clinical Professor, Department of Internal Medicine, Division of Dermatology, University of Missouri at Kansas City; Private Practice, American Dermatology Associates, LLC
Donald Belsito, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Contact Dermatitis Society, Dermatology Foundation, Kansas Medical Society, Noah Worcester Dermatological Society, Phi Beta Kappa, and Phi Beta Kappa
Disclosure: Nothing to disclose.

Pharmacy Editor

Richard P Vinson, MD, Assistant Clinical Professor, Department of Dermatology, Texas Tech University School of Medicine; Consulting Staff, Mountain View Dermatology, PA
Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Association of Military Dermatologists, Texas Dermatological Society, and Texas Medical Association
Disclosure: Nothing to disclose.

Managing Editor

Jeffrey P Callen, MD, Professor of Medicine, Chief, Division of Dermatology, University of Louisville School of Medicine
Jeffrey P Callen, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American College of Physicians, and American College of Rheumatology
Disclosure: Amgen Honoraria Consulting; Abbott Honoraria Consulting; Electrical Optical Sciences Honoraria Consulting; Centocor Honoraria Consulting; Genetech Honoraria Consulting; Celgene Honoraria Consulting

CME Editor

Catherine Quirk, MD, Clinical Assistant Professor, Department of Dermatology, Brown University
Catherine Quirk, MD is a member of the following medical societies: Alpha Omega Alpha and American Academy of Dermatology
Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD, Director, Department of Dermatology, Geisinger Medical Center
Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology
Disclosure: Nothing to disclose.

 
 
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