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Dermatologic Manifestations of Pellagra Differential Diagnoses

  • Author: Vladimir Hegyi, MD, PhD; Chief Editor: Dirk M Elston, MD  more...
 
Updated: Feb 22, 2016
 
 

Diagnostic Considerations

Also consider the following:

  • Photodermatitis
  • Actinic reticuloid
  • Concomitant zinc deficiency
  • Pellagrous vulvitis
  • Pellagrous vaginitis
  • Pellagrous scrotal dermatitis
  • Contact dermatitis
  • Pyridoxine deficiency
  • Riboflavin deficiency
  • Vitamin B-12 deficiency
  • Drug eruptions - Distinguished by the drug history, clinical picture, localization, configuration, development of skin symptoms, and evidence of exposure to drug allergens
  • Dermatitis solaris - Distinguished by the history, clinical picture, monomorphism, localization, exposed sites, development of skin symptoms, lack of marked pigmentation, and fast healing
  • Eczema solare - Distinguished by the history, clinical picture, polymorphism, development of skin symptoms, lack of marked pigmentation, and itching
  • Eczema - Distinguished by the clinical picture, localization, development of skin symptoms, lack of marked pigmentation, and histology
  • Pemphigus vulgaris - Distinguished by the clinical picture, bullae on unchanged skin, localization, cytodiagnostics, and histologic features
  • Lupus erythematosus acutus et subacutus disseminatus - Distinguished by the general state, variable skin manifestation, infiltrates, red wine–colored transient erythemas on the palms and digits, lupus erythematosus phenomenon, proteinuria, and cylindruria
  • Chronic polymorphic light dermatoses - Distinguished by erythema on light-exposed sites, recurring papules, pruriginous nodules, lichenification, lack of marked pigmentation, and scaling
  • Hartnup syndrome - Recessive hereditary disorder distinguished by the malabsorption of tryptophan, pellagrous skin lesions, hypersensitivity to sun exposure, poikiloderma, onset in childhood, absence of mucous membrane disorder and diarrhea, various nervous and psychiatric aberrations, intermittent cerebellar ataxia, aminoaciduria, and marked indicanuria
  • Kwashiorkor - Distinguished by occurrence in children, dietary history, protein deficiency, generalized eruption, dermatitis with systemic signs of apathy and edema, thin and light hair, and high mortality rate
  • Porphyria cutanea tarda - Distinguished by bullae on exposed sites, bullae development after mechanical injury, porphyrins in the urine, and characteristic liver function test findings and medical findings in the liver
  • Porphyria variegata - Distinguished by erythema and bullae, skin and abdominal symptoms in attacks, and porphyrins in the urine and stool

Differential Diagnoses

 
 
Contributor Information and Disclosures
Author

Vladimir Hegyi, MD, PhD Professor, Institute of Clinical and Experimental Dermatovenereology, Slovak Republic

Vladimir Hegyi, MD, PhD is a member of the following medical societies: European Academy of Dermatology and Venereology, Slovakian Dermatovenerological Society, European Dermatology Forum

Disclosure: Nothing to disclose.

Coauthor(s)

Robert A Schwartz, MD, MPH Professor and Head of Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, Rutgers New Jersey Medical School; Visiting Professor, Rutgers University School of Public Affairs and Administration

Robert A Schwartz, MD, MPH is a member of the following medical societies: Alpha Omega Alpha, New York Academy of Medicine, American Academy of Dermatology, American College of Physicians, Sigma Xi

Disclosure: Nothing to disclose.

Specialty Editor Board

David F Butler, MD Section Chief of Dermatology, Central Texas Veterans Healthcare System; Professor of Dermatology, Texas A&M University College of Medicine; Founding Chair, Department of Dermatology, Scott and White Clinic

David F Butler, MD is a member of the following medical societies: American Medical Association, Alpha Omega Alpha, Association of Military Dermatologists, American Academy of Dermatology, American Society for Dermatologic Surgery, American Society for MOHS Surgery, Phi Beta Kappa

Disclosure: Nothing to disclose.

Jeffrey J Miller, MD Associate Professor of Dermatology, Pennsylvania State University College of Medicine; Staff Dermatologist, Pennsylvania State Milton S Hershey Medical Center

Jeffrey J Miller, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, Society for Investigative Dermatology, Association of Professors of Dermatology, North American Hair Research Society

Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

References
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