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Jessner Lymphocytic Infiltration of the Skin Differential Diagnoses

  • Author: Kara Melissa T Torres, MD, DPDS; Chief Editor: William D James, MD  more...
 
Updated: Jan 12, 2015
 
 

Differential Diagnoses

  • Cutaneous lymphoid hyperplasia

  • Cutaneous lymphoma

  • Granuloma Annulare

  • Granuloma Faciale

  • Gyrate erythema

  • Lupus erythematosus tumidus

  • Plaque form of polymorphous light reaction

  • Reticular erythematous mucinosis

 
 
Contributor Information and Disclosures
Author

Kara Melissa T Torres, MD, DPDS Visiting Research Fellow, Ackerman Academy of Dermatopathology

Kara Melissa T Torres, MD, DPDS is a member of the following medical societies: Philippine Dermatological Society

Disclosure: Nothing to disclose.

Coauthor(s)

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Specialty Editor Board

Richard P Vinson, MD Assistant Clinical Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine; Consulting Staff, Mountain View Dermatology, PA

Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Texas Medical Association, Association of Military Dermatologists, Texas Dermatological Society

Disclosure: Nothing to disclose.

Daniel S Loo, MD Associate Professor of Dermatology, Residency Program Director, Department of Dermatology, Tufts Medical Center

Daniel S Loo, MD is a member of the following medical societies: American Academy of Dermatology, Association of Professors of Dermatology

Disclosure: Nothing to disclose.

Chief Editor

William D James, MD Paul R Gross Professor of Dermatology, Vice-Chairman, Residency Program Director, Department of Dermatology, University of Pennsylvania School of Medicine

William D James, MD is a member of the following medical societies: American Academy of Dermatology, Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Acknowledgements

Mohsin Ali, MBBS, MRCP, MRCPI Consulting Staff, Department of Dermatology, Amersham General Hospital, UK

Disclosure: Nothing to disclose.

Peter Fritsch, MD Chair, Department of Dermatology and Venereology, University of Innsbruck, Austria

Peter Fritsch, MD is a member of the following medical societies: American Dermatological Association, International Society of Pediatric Dermatology, and Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Sohail Mansoor, MBBS, MSc Dermatologist and Lead Physician in Dermatologic Surgery, Department of Dermatology, Barnet Hospital, UK

Sohail Mansoor, MBBS, MSc is a member of the following medical societies: American Academy of Anti-Aging Medicine, American Academy of Dermatology, American Society for Dermatologic Surgery, Royal College of Physicians and Surgeons of Glasgow, and Royal College of Physicians of the United Kingdom

Disclosure: Nothing to disclose.

Nicole Sakka, MBBS Foundation Year 2, Royal Liverpool and Broadgreen University Hospital, Liverpool, UK

Disclosure: Nothing to disclose.

Marjan Shah, MBBS, Msc Dermatology (UK) Specialty Physician in Dermatology, Milton Keynes NHS Trust, UK

Disclosure: Nothing to disclose.

Bassam Zeina, MD, PhD Consulting Staff, Department of Dermatology, Milton Keynes Hospital, UK

Bassam Zeina, MD, PhD is a member of the following medical societies: British Association of Dermatologists, British Medical Association, and Royal Society of Medicine

Disclosure: Nothing to disclose.

References
  1. Jessner M, Kanof NB. Lymphocytic infiltration of the skin. Arch Dermatol. 1953. 68:447-9.

  2. Lipsker D, Mitschler A, Grosshans E, Cribier B.Could Jessner's lymphocytic infiltrate of the skin be a dermal variant of lupus erythematosus? An analysis of 210 cases.Dermatology. 2006;213(1):15-22.

  3. James WD, Berger TG, Elston DE, eds. Clinical Dermatology. Andrews' Diseases of the Skin. 10th ed. Elsevier Saunders; 2006.

  4. Dippel E, Poenitz N, Klemke CD, Orfanos CE, Goerdt S. Familial lymphocytic infiltration of the skin: histochemical and molecular analysis in three brothers. Dermatology. 2002. 204(1):12-6. [Medline].

  5. Ziemer M, Eisendle K, Müller H, Zelger B. Lymphocytic infiltration of the skin (Jessner-Kanof) but not reticular erythematous mucinosis occasionally represents clinical manifestations of Borrelia-associated pseudolymphoma. Br J Dermatol. 2009 Sep. 161(3):583-90. [Medline].

  6. Bolognia JL, Jorizzo JL, Schaffer JV, eds. Dermatology. 3rd ed. Elsevier Saunders; 2012.

  7. Braddock SW, Kay HD, Maennle D, McDonald TL, Pirruccello SJ, Masih A, et al. Clinical and immunologic studies in reticular erythematous mucinosis and Jessner's lymphocytic infiltrate of skin. J Am Acad Dermatol. 1993 May. 28(5 Pt 1):691-5. [Medline].

  8. Weber F, Schmuth M, Fritsch P, Sepp N. Lymphocytic infiltration of the skin is a photosensitive variant of lupus erythematosus: evidence by phototesting. Br J Dermatol. 2001 Feb. 144(2):292-6. [Medline].

  9. Rémy-Leroux V, Léonard F, Lambert D, Wechsler J, Cribier B, Thomas P, et al. Comparison of histopathologic-clinical characteristics of Jessner's lymphocytic infiltration of the skin and lupus erythematosus tumidus: Multicenter study of 46 cases. J Am Acad Dermatol. 2008 Feb. 58(2):217-23. [Medline].

  10. Tomasini D, Mentzel T, Hantschke M, Cerri A, Paredes B, Rütten A, et al. Plasmacytoid dendritic cells: an overview of their presence and distribution in different inflammatory skin diseases, with special emphasis on Jessner's lymphocytic infiltrate of the skin and cutaneous lupus erythematosus. J Cutan Pathol. 2010 Nov. 37(11):1132-9. [Medline].

  11. Schepis C, Lentini M, Siragusa M, Batolo D. ACE-inhibitor-induced drug eruption resembling lymphocytic infiltration (of Jessner-Kanof) and Lupus erythematosus tumidus. Dermatology. 2004. 208(4):354-5. [Medline].

  12. Nolden S, Casper C, Kuhn A, Petereit HF. Jessner-Kanof lymphocytic infiltration of the skin associated with glatiramer acetate. Mult Scler. 2005 Apr. 11(2):245-8. [Medline].

  13. Adamski H, Labrousse AL, Sparsa A, Leonard F, Le Gall F, Labrousse F, et al. [Positive photobiological investigation in Jessner's lymphocytic infiltration of the skin]. Ann Dermatol Venereol. 2002 Dec. 129(12):1370-3. [Medline].

  14. Awotesu S, Dubois V, El-Hindy N, Watts M. Jessner's lymphocytic infiltrate: a rare cause of lid ectropion. BMJ Case Rep. 2010. 2010:[Medline]. [Full Text].

  15. Poenitz N, Dippel E, Klemke CD, Qadoumi M, Goerdt S. Jessner's lymphocytic infiltration of the skin: a CD8+ polyclonal reactive skin condition. Dermatology. 2003. 207(3):276-84. [Medline].

  16. Wolf M. Lymphocytic infiltration of the face. Arch Dermatol. 1957. 75:136.

  17. Bahillo-Monné C, Heras-Mendaza F, Casado-Fariñas I, Gatica-Ortega M, Conde-Salazar L. Jessner's lymphocytic infiltrate as a Koebner response to patch test. Contact Dermatitis. 2007 Sep. 57(3):197-9. [Medline].

  18. Ashworth J, Turbitt M, MacKie R. A comparison of the dermal lymphoid infiltrates in discoid lupus erythematosus and Jessner's lymphocytic infiltrate of the skin using the monoclonal antibody Leu 8. J Cutan Pathol. 1987 Aug. 14(4):198-201. [Medline].

  19. Kunz M, Henseleit-Walter U, Sorg C, Kolde G. Macrophage marker 27E10 on human keratinocytes helps to differentiate discoid lupus erythematosus and Jessner's lymphocytic infiltration of the skin. Eur J Dermatol. 1999 Mar. 9(2):107-10. [Medline].

  20. Rijlaarsdam JU, Nieboer C, de Vries E, Willemze R. Characterization of the dermal infiltrates in Jessner's lymphocytic infiltrate of the skin, polymorphous light eruption and cutaneous lupus erythematosus: differential diagnostic and pathogenetic aspects. J Cutan Pathol. 1990 Feb. 17(1):2-8. [Medline].

  21. Willemze R, Dijkstra A, Meijer CJ. Lymphocytic infiltration of the skin (Jessner): a T-cell lymphoproliferative disease. Br J Dermatol. 1984 May. 110(5):523-9. [Medline].

  22. Laurinaviciene R, Clemmensen O, Bygum A.Successful treatment of Jessner's lymphocytic infiltration of the skin with methotrexate.Acta Derm Venereol .2009;89(5):542-3.

  23. Wu JJ, Huang DB, Pang KR, Hsu S, Tyring SK. Thalidomide: dermatological indications, mechanisms of action and side-effects. Br J Dermatol. 2005 Aug. 153(2):254-73. [Medline].

  24. Hafejee A, Winhoven S, Coulson IH. Jessner's lymphocytic infiltrate responding to oral auranofin. J Dermatolog Treat. 2004 Sep. 15(5):331-2. [Medline].

  25. Green CM.Clin Exp Dermatol.Successful treatment of Jessner's lymphocytic infiltrate with auranofin.Clin Exp Dermatol. 2008 Jan;33(1):108-9.

  26. Ordi-Ros J, Cosiglio FJ. [Current therapeutic indications of thalidomide and lenalidomide]. Med Clin (Barc). 2014 Apr 22. 142(8):360-4. [Medline].

  27. Borges da Costa J, Boixeda P, Moreno C. Pulsed-dye laser treatment of Jessner lymphocytic infiltration of the skin. J Eur Acad Dermatol Venereol. 2008 Sep 1. [Medline].

  28. Michel JL, Perrin D. [Pulsed dye laser treatment for Jessner's lymphocytic infiltration of the skin]. Ann Dermatol Venereol. 2010 Dec. 137(12):803-7. [Medline].

  29. Park KY, Kim HK, Li K, Kim BJ, Seo SJ, Kim MN, et al. Photodynamic therapy: new treatment for refractory lymphocytic infiltration of the skin. Clin Exp Dermatol. 2012 Feb 2. [Medline].

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