Erythroplasia of Queyrat (Bowen Disease of the Glans Penis)

Updated: Mar 31, 2016
  • Author: Vikas Shrivastava, MD; Chief Editor: Dirk M Elston, MD  more...
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Overview

Background

Erythroplasia of Queyrat (EQ) is an in situ squamous cell carcinoma of the penis. [1] The glans and prepuce are most commonly involved. Erythroplasia of Queyrat is seen almost exclusively in uncircumcised men. Progression to invasive carcinoma may occur, and spontaneous regression is unlikely. [2, 3]

Erythroplasia of Queyrat was originally described by Tarnovsky in 1891 and later appreciated as a penile disease by Fournier and Darier in 1893. Studies by Queyrat in 1911 allowed erythroplasia of Queyrat to be accepted as a distinct entity. In 1933, Sulzberger and Satenstein recognized erythroplasia of Queyrat as a form of carcinoma in situ. [4]

Some references equate erythroplasia of Queyrat with the term Bowen disease of the glans penis”. [5] The term erythroplasia of Queyrat is used for squamous cell carcinoma in situ (SCCIS) of the mucocutaneous epithelium of the penis. [1]

Some references extend use of the term erythroplasia of Queyrat to also describe SCCIS of the labia minora, vestibule, vulva, labia majora, conjunctivae, buccal mucosa, and anal mucosa. [1, 3, 6]

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Epidemiology

Frequency

Erythroplasia of Queyrat is a rarely reported disorder. It makes up less than 1% of malignancies in males. [5]

Age

Erythroplasia of Queyrat is a disease of middle-aged to elderly males. [7] It has been described in males ranging from age 20-80 years. [8]

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