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Eccrine Carcinoma Follow-up

  • Author: Anthony Wong, MD, FAAD; Chief Editor: Dirk M Elston, MD  more...
 
Updated: Feb 28, 2014
 

Deterrence/Prevention

See the list below:

  • Sun protection would be prudent to the extent that UVR is considered a potential causative factor in eccrine carcinoma; however, this is only speculative at this point.
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Complications

See the list below:

  • Eccrine carcinomas may cause complications secondary to local invasion or metastatic disease.
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Prognosis

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  • After studying a group of 35 patients with a limited variety of eccrine carcinoma subtypes, Mehregan et al[21] concluded that while all have a tendency for local recurrence, local lymphatic spread or distant metastasis occurs in less than 10% of cases. Indeed, the precise behavior of a given tumor seems to correlate well with its histologic subtype. While the prognosis for disseminated disease is believed to be grim, insufficient experience exists to allow tabulation of specific survival data.
    • Sclerosing sweat duct carcinoma and primary cutaneous adenoid cystic carcinoma have been implicated in local recurrences only.[22]
    • Eccrine adenocarcinoma, malignant chondroid syringoma, and malignant nodular hidradenoma are particularly prone to metastasize.[23]
    • Porocarcinoma also may metastasize widely.
    • Malignant eccrine spiradenoma reportedly spreads to regional lymph nodes and systemically, but too few cases have been described to enable a generalized statement regarding the behavior of this tumor.
    • Mucinous eccrine carcinoma occasionally spreads to regional nodes but only rarely metastasizes.
    • Aggressive digital papillary tumors are locally destructive but also metastasize not infrequently (14% in one study).[24]
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Contributor Information and Disclosures
Author

Anthony Wong, MD, FAAD Consulting Staff, Department of Dermatology, SUNY Health Science Center at Brooklyn, St Catherine's of Sienna, and Long Island Skin Cancer and Dermatologic Surgery, PC

Anthony Wong, MD, FAAD is a member of the following medical societies: American Academy of Dermatology, American College of Mohs Surgery

Disclosure: Nothing to disclose.

Coauthor(s)

Daniel Mark Siegel, MD, MS Clinical Professor of Dermatology, Department of Dermatology, State University of New York Downstate Medical Center

Daniel Mark Siegel, MD, MS is a member of the following medical societies: American Academy of Dermatology, American College of Mohs Surgery, American Association for Physician Leadership, American Society for Dermatologic Surgery, American Society for MOHS Surgery, International Society for Dermatologic Surgery

Disclosure: Nothing to disclose.

Darren Keith Mollick, MD Clinical Assistant Professor, Department of Dermatology, State University of New York Downstate Medical Center

Disclosure: Nothing to disclose.

Specialty Editor Board

Richard P Vinson, MD Assistant Clinical Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine; Consulting Staff, Mountain View Dermatology, PA

Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Texas Medical Association, Association of Military Dermatologists, Texas Dermatological Society

Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Additional Contributors

R Stan Taylor, MD The JB Howell Professor in Melanoma Education and Detection, Departments of Dermatology and Plastic Surgery, Director, Skin Surgery and Oncology Clinic, University of Texas Southwestern Medical Center

R Stan Taylor, MD is a member of the following medical societies: American Academy of Dermatology, American College of Mohs Surgery, American Medical Association

Disclosure: Nothing to disclose.

Acknowledgements

Mary Farley, MD Dermatologic Surgeon/Mohs Surgeon, Anne Arundel Surgery Center

Disclosure: Nothing to disclose.

Aza Lefkowitz, MD Consulting Staff, Advanced Dermatology, PC

Disclosure: Nothing to disclose.

References
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