eMedicine Specialties > Dermatology > Malignant Neoplasms
Eccrine Carcinoma: Treatment & Medication
Updated: Oct 14, 2008
- Overview
- Differential Diagnoses & Workup
- Treatment & Medication
- Follow-up
Treatment
Medical Care
Experience and published data are very sparse. Radiation therapy has been used in select cases; chemotherapy has not been used extensively and presumably is lacking in efficacy.11
Surgical Care
Mohs micrographic surgery is becoming the mainstay of therapy. Specific surgical treatments administered (as described in isolated case reports) for a few of these subtypes are detailed below.
- MAC: A review of the world literature, which included 13 previously unpublished cases, reported 73 cases of MAC treated with Mohs; 39 of these were followed for more than 2 years with only 4 recurrences (89.7% success rate).12 A later review of 10 cases of MAC treated with Mohs reported disease free periods of 23.3 months, compared to one recurrence with standard surgical excision.
- Eccrine porocarcinoma: In a review of 9 cases from 1986-1996, 8 were treated with wide excision and 1 was treated with radiotherapy (RT); only 1 of the excisional cases and the RT case recurred.13
- Malignant eccrine spiradenoma: A few case reports exist of this tumor treated with wide excision with or without radiation therapy. However, long-term data are scant.
- Aggressive digital papillary adenocarcinoma: Wide excision or amputation of the affected digit has been advised.
- Primary cutaneous adenoid cystic carcinoma: A report on 8 patients treated with wide excision noted 3 recurrences (time period unspecified) with 1 patient lost to follow-up.
The Medscape Dermatologic Surgery Resource Center may be of interest.
Consultations
Surgical oncologists, medical oncologists, and radiation therapists may play roles in the treatment of patients with eccrine carcinoma.
More on Eccrine Carcinoma |
| Overview: Eccrine Carcinoma |
| Differential Diagnoses & Workup: Eccrine Carcinoma |
Treatment & Medication: Eccrine Carcinoma |
| Follow-up: Eccrine Carcinoma |
| References |
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References
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Further Reading
Keywords
eccrine carcinoma, eccrine adenocarcinoma, malignant tumors with eccrine differentiation, EC
Treatment & Medication: Eccrine Carcinoma