Liposarcoma Differential Diagnoses
- Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD more...
Antonescu CR. The role of genetic testing in soft tissue sarcoma. Histopathology. Jan 2006;48(1):13-21. [Medline].
Binh MB, Sastre-Garau X, Guillou L, et al. MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: a comparative analysis of 559 soft tissue neoplasms with genetic data. Am J Surg Pathol. Oct 2005;29(10):1340-7. [Medline].
Skubitz KM, Cheng EY, Clohisy DR, Thompson RC, Skubitz AP. Differential gene expression in liposarcoma, lipoma, and adipose tissue. Cancer Invest. 2005;23(2):105-18. [Medline].
Tayal S, Classen E, Bemis L, Robinson WA. C-kit expression in dedifferentiated and well-differentiated liposarcomas; immunohistochemistry and genetic analysis. Anticancer Res. May-Jun 2005;25(3B):2215-20. [Medline].
Vocks E, Worret WI, Burgdorf WH. Myxoid liposarcoma in a 12-year-old girl. Pediatr Dermatol. Mar-Apr 2000;17(2):129-32. [Medline].
Paredes BE, Mentzel T. Atypical Lipomatous Tumor/"Well-Differentiated Liposarcoma" of the Skin Clinically Presenting as a Skin Tag: Clinicopathologic, Immunohistochemical, and Molecular Analysis of 2 Cases. Am J Dermatopathol. Feb 24 2011;[Medline].
Gardner JM, Dandekar M, Thomas D, Goldblum JR, Weiss SW, Billings SD, et al. Cutaneous and Subcutaneous Pleomorphic Liposarcoma: A Clinicopathologic Study of 29 Cases With Evaluation of MDM2 Gene Amplification in 26. Am J Surg Pathol. Mar 31 2012;[Medline].
Mustacchio V, Cabibi D, Minervini MI, Barresi E, Amato S. A diagnostic trap for the dermatopathologist: granulomatous reactions from cutaneous microimplants for cosmetic purposes. J Cutan Pathol. Mar 2007;34(3):281-3. [Medline].
Gonçales ES, Almeida AS, Soares S, Oliveira DT. Silicone implant for chin augmentation mimicking a low-grade liposarcoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. Apr 2009;107(4):e21-3. [Medline].
Nascimento AF, Bertoni F, Fletcher CD. Epithelioid variant of myxofibrosarcoma: expanding the clinicomorphologic spectrum of myxofibrosarcoma in a series of 17 cases. Am J Surg Pathol. Jan 2007;31(1):99-105. [Medline].
Chan WY, McHenry ID, Carter LM, Reall G, Wales CJ. Gingival liposarcoma: an unusual polyp. Br J Oral Maxillofac Surg. Mar 2008;46(2):150-1. [Medline].
McElderry J, McKenney JK, Stack BC. High-grade liposarcoma metastatic to the gingival mucosa: case report and literature review. Am J Otolaryngol. Mar-Apr 2008;29(2):130-4. [Medline].
Olaleye O, Fu B, Moorthy R, Lawson C, Black M, Mitchell D. Left supraclavicular spindle cell lipoma. Int J Otolaryngol. 2010;2010:942152. [Medline].
Brandal P, Bjerkehagen B, Heim S. Rearrangement of chromosomal region 8q11-13 in lipomatous tumours: correlation with lipoblastoma morphology. J Pathol. Feb 2006;208(3):388-94. [Medline].
Brenner W, Eary JF, Hwang W, Vernon C, Conrad EU. Risk assessment in liposarcoma patients based on FDG PET imaging. Eur J Nucl Med Mol Imaging. Nov 2006;33(11):1290-5. [Medline].
Weaver J, Rao P, Goldblum JR, Joyce MJ, Turner SL, Lazar AJ, et al. Can MDM2 analytical tests performed on core needle biopsy be relied upon to diagnose well-differentiated liposarcoma?. Mod Pathol. May 21 2010;[Medline].
Jones RL, Fisher C, Al-Muderis O, Judson IR. Differential sensitivity of liposarcoma subtypes to chemotherapy. Eur J Cancer. Dec 2005;41(18):2853-60. [Medline].
Oda Y, Yamamoto H, Takahira T, et al. Frequent alteration of p16(INK4a)/p14(ARF) and p53 pathways in the round cell component of myxoid/round cell liposarcoma: p53 gene alterations and reduced p14(ARF) expression both correlate with poor prognosis. J Pathol. Dec 2005;207(4):410-21. [Medline].
Dalal KM, Antonescu CR, Singer S. Diagnosis and management of lipomatous tumors. J Surg Oncol. Mar 15 2008;97(4):298-313. [Medline].
Sharma PK, Janniger CK, Schwartz RA, Rauscher GE, Lambert WC. The treatment of atypical lipoma with liposuction. J Dermatol Surg Oncol. Apr 1991;17(4):332-4. [Medline].
Hogg ME, Wayne JD. Atypical lipomatous tumor/well-differentiated liposarcoma: what is it?. Surg Oncol Clin N Am. Apr 2012;21(2):333-40. [Medline].
Nishida Y, Tsukushi S, Nakashima H, Ishiguro N. Clinicopathologic Prognostic Factors of Pure Myxoid Liposarcoma of the Extremities and Trunk Wall. Clin Orthop Relat Res. May 25 2010;[Medline].
Turcotte RE, Ferrone M, Isler MH, Wong C. Outcomes in patients with popliteal sarcomas. Can J Surg. Feb 2009;52(1):51-5. [Medline].
Tebes S, Cardosi R, Hoffman M. Liposarcoma complicating pregnancy. Gynecol Oncol. Dec 2001;83(3):610-2. [Medline].
Allen PW, Strungs I, MacCormac LB. Atypical subcutaneous fatty tumors: a review of 37 referred cases. Pathology. May 1998;30(2):123-35. [Medline].
Azumi N, Curtis J, Kempson RL, Hendrickson MR. Atypical and malignant neoplasms showing lipomatous differentiation. A study of 111 cases. Am J Surg Pathol. Mar 1987;11(3):161-83. [Medline].
Dei Tos AP, Mentzel T, Fletcher CD. Primary liposarcoma of the skin: a rare neoplasm with unusual high grade features. Am J Dermatopathol. Aug 1998;20(4):332-8. [Medline].
Deyrup AT, Weiss SW. Grading of soft tissue sarcomas: the challenge of providing precise information in an imprecise world. Histopathology. Jan 2006;48(1):42-50. [Medline].
Enzinger FM, Weiss SW. Liposarcoma. In: Enzinger and Weiss's Soft Tissue Tumors. 3rd ed. Mosby-Year Book; 1995.
Evans HL. Liposarcomas and atypical lipomatous tumors. A study of 66 cases followed for a minimum of 10 years. Surg Pathol. 1988;1:41.
Fleishman JS, Schwartz RA. Hibernoma: ultrastructural observations. J Surg Oncol. Aug 1983;23(4):285-9. [Medline].
Guillén DR, Cockerell CJ. Cutaneous and subcutaneous sarcomas. Clin Dermatol. May-Jun 2001;19(3):262-8. [Medline].
Mathew R, Morgan MB. Dermal atypical lipomatous tumor/well-differentiated liposarcoma obfuscated by epidermal inclusion cyst: a wolf in sheep's clothing?. Am J Dermatopathol. Aug 2006;28(4):338-40. [Medline].
Matushansky I, Hernando E, Socci ND, et al. A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas. Am J Pathol. Apr 2008;172(4):1069-80. [Medline].
McCormick D, Mentzel T, Beham A, Fletcher CD. Dedifferentiated liposarcoma. Clinicopathologic analysis of 32 cases suggesting a better prognostic subgroup among pleomorphic sarcomas. Am J Surg Pathol. Dec 1994;18(12):1213-23. [Medline].
Mentzel T. Cutaneous lipomatous neoplasms. Semin Diagn Pathol. Nov 2001;18(4):250-7. [Medline].
Mentzel T. [Lipomatous tumors of the skin and soft tissue. New entities and concepts]. Pathologe. Nov 2000;21(6):441-8. [Medline].
Nemanqani D, Mourad WA, Akhtar M, et al. Liposarcoma: A clinicopathological study of 73 cases diagnosed at King Faisal Specialist Hospital and Research Centre. Ann Saudi Med. Jul-Aug 1999;19(4):299-303. [Medline].
Reis-Filho JS, Milanezi F, Soares MF, Fillus-Neto J, Schmitt FC. Intradermal spindle cell/pleomorphic lipoma of the vulva: case report and review of the literature. J Cutan Pathol. Jan 2002;29(1):59-62. [Medline].
Uenotsuchi T, Imafuku S, Moroi Y, Urabe K, Furue M. Large subcutaneous liposarcoma arising from the chest wall. Eur J Dermatol. Jan-Feb 2005;15(1):43-5. [Medline].
Weitzner S, Kornblum S. Subcutaneous liposarcoma of forearm. Am Surg. Mar 1972;38(3):176-8. [Medline].

