eMedicine Specialties > Dermatology > Metabolic Diseases

Protein-Energy Malnutrition: Follow-up

Author: Noah S Scheinfeld, MD, JD, FAAD, Assistant Clinical Professor, Department of Dermatology, Columbia University; Consulting Staff, Department of Dermatology, St Luke's Roosevelt Hospital Center, Beth Israel Medical Center, New York Eye and Ear Infirmary; Private Practice
Coauthor(s): Anusuya Mokashi, MS, Medical Student, New York Medical College; Andrew Lin, MD, FRCPC, Associate Professor, Department of Internal Medicine, Division of Dermatology, University of Alberta
Contributor Information and Disclosures

Updated: Feb 18, 2008

Follow-up

Further Outpatient Care

  • Patients should receive follow-up care with nutrition professionals and social services.

Prognosis

  • The extent of growth failure and the severity of hypoproteinemia, hypoalbuminemia, and electrolyte imbalances are predictors of a poorer prognosis.
  • Underlying HIV infection is associated with a poor prognosis.
 
Acknowledgments

The authors and editors of eMedicine gratefully acknowledge the contributions of previous author, Dr. Dino Santoro, to the development and writing of this article.



More on Protein-Energy Malnutrition

Overview: Protein-Energy Malnutrition
Differential Diagnoses & Workup: Protein-Energy Malnutrition
Treatment & Medication: Protein-Energy Malnutrition
Follow-up: Protein-Energy Malnutrition
References

References

  1. Onis M de, Monteiro C, Clugston G. The worldwide magnitude of protein-energy malnutrition: an overview from the WHO Global Database on Child Growth. Bulletin of the World Health Organization. 1993;71(6).

  2. Lin CA, Boslaugh S, Ciliberto HM, Maleta K, Ashorn P, Briend A, et al. A prospective assessment of food and nutrient intake in a population of Malawian children at risk for kwashiorkor. J Pediatr Gastroenterol Nutr. Apr 2007;44(4):487-93. [Medline].

  3. World Health Organization, Dept of Nutrition for Health and Development. Nutrition for health and development: a global agenda for combating malnutrition. World Health Organization. Available at http://whqlibdoc.who.int/hq/2000/WHO_NHD_00.6.pdf.

  4. Lewandowski H, Breen TL, Huang EY. Kwashiorkor and an acrodermatitis enteropathica-like eruption after a distal gastric bypass surgical procedure. Endocr Pract. May-Jun 2007;13(3):277-82. [Medline].

  5. Tavarela Veloso F. Review article: skin complications associated with inflammatory bowel disease. Aliment Pharmacol Ther. Oct 2004;20 Suppl 4:50-3. [Medline].

  6. Demling RH. The incidence and impact of pre-existing protein energy malnutrition on outcome in the elderly burn patient population. J Burn Care Rehabil. 2005;Jan-Feb;26(1):94-100. [Medline].

  7. Thavaraj V, Sesikeran B. Histopathological changes in skin of children with clinical protein energy malnutrition before and after recovery. J Trop Pediatr. Jun 1989;35(3):105-8. [Medline].

  8. McKenzie CA, Wakamatsu K, Hanchard NA, Forrester T, Ito S. Childhood malnutrition is associated with a reduction in the total melanin content of scalp hair. Br J Nutr. Jul 2007;98(1):159-64. [Medline].

  9. Chung SH, Stenvinkel P, Lindholm B, Avesani CM. Identifying and managing malnutrition stemming from different causes. Perit Dial Int. Jun 2007;27 Suppl 2:S239-44. [Medline].

  10. Balint JP. Physical findings in nutritional deficiencies. Pediatr Clin North Am. Feb 1998;45(1):245-60. [Medline].

  11. Beers MH, Berkow R, eds. Nutritional Disorders: Malnutrition. In: The Merck Manual. 17th ed. Merck; 1999:28-32.

  12. Caksen H, Kendirci M, Kandemir O, Patiroglu T. A case of malignant histiocytosis associated with skin involvement mimicking kwashiorkor. Pediatr Dermatol. Nov-Dec 2001;18(6):545-6. [Medline].

  13. Collins N. Protein-energy malnutrition and involuntary weight loss: nutritional and pharmacological strategies to enhance wound healing. Expert Opin Pharmacother. Jul 2003;4(7):1121-40. [Medline].

  14. Constans T, Alix E, Dardaine V. [Protein-energy malnutrition. Diagnostic methods and epidemiology]. Presse Med. Dec 16 2000;29(39):2171-6. [Medline].

  15. De Caprio C, Alfano A, Senatore I, Zarrella L, Pasanisi F, Contaldo F. Severe acute liver damage in anorexia nervosa: two case reports. Nutrition. May 2006;22(5):572-5. [Medline].

  16. Delahoussaye AR, Jorizzo JL. Cutaneous manifestations of nutritional disorders. Dermatol Clin. Jul 1989;7(3):559-70. [Medline].

  17. Gehri M, Stettler N, Di Paolo ER. Marasmus. eMedicine from WebMD [serial online]. May 22, 2006;Available at http://www.emedicine.com/ped/topic164.htm.

  18. Glaser, KL. Pediatrics: Malnutrition. Medstudents. Available at http://www.medstudents.com.br/pedia/pedia1.htm.

  19. Golden MHN. Severe malnutrition. In: Weatherall DJ, Ledingham JGG, Warrell DA, eds. Oxford Textbook of Medicine. 3rd ed. 1996:1278-96.

  20. Goskowicz M, Eichenfield LF. Cutaneous findings of nutritional deficiencies in children. Curr Opin Pediatr. Aug 1993;5(4):441-5. [Medline].

  21. Grigsby DG. Malnutrition. eMedicine from WebMD [serial online]. June 30, 2006;Available at http://www.emedicine.com/ped/topic1360.htm.

  22. Gupta MA, Gupta AK, Haberman HF. Dermatologic signs in anorexia nervosa and bulimia nervosa. Arch Dermatol. Oct 1987;123(10):1386-90. [Medline].

  23. Gurski RR, Schirmer CC, Rosa AR, Brentano L. Nutritional assessment in patients with squamous cell carcinoma of the esophagus. Hepatogastroenterology. Nov-Dec 2003;50(54):1943-7. [Medline].

  24. Harris CL, Fraser C. Malnutrition in the institutionalized elderly: the effects on wound healing. Ostomy Wound Manage. Oct 2004;50(10):54-63. [Medline].

  25. Hendricks KM, Duggan C, Gallagher L, Carlin AC, Richardson DS, Collier SB, et al. Malnutrition in hospitalized pediatric patients. Current prevalence. Arch Pediatr Adolesc Med. Oct 1995;149(10):1118-22. [Medline].

  26. Jilcott SB, Masso KL, Ickes SB, Myhre SD, Myhre JA. Surviving but not quite thriving: anthropometric survey of children aged 6 to 59 months in a rural Western Uganda district. J Am Diet Assoc. Nov 2007;107(11):1983-8. [Medline].

  27. Kuhl J, Davis MD, Kalaaji AN, Kamath PS, Hand JL, Peine CJ. Skin signs as the presenting manifestation of severe nutritional deficiency: report of 2 cases. Arch Dermatol. May 2004;140(5):521-4. [Medline].

  28. Lyder CH. Assessing risk and preventing pressure ulcers in patients with cancer. Semin Oncol Nurs. Aug 2006;22(3):178-84. [Medline].

  29. Manguso F, D'Ambra G, Menchise A, et al. Effects of an appropriate oral diet on the nutritional status of patients with HCV-related liver cirrhosis: a prospective study. Clin Nutr. Oct 2005;24(5):751-9. [Medline].

  30. McLaren DS. Skin in protein energy malnutrition. Arch Dermatol. Dec 1987;123(12):1674-1676a. [Medline].

  31. Miller SJ. Nutritional deficiency and the skin. J Am Acad Dermatol. Jul 1989;21(1):1-30. [Medline].

  32. Neldner KH. Nutrition, aging and the skin. Geriatrics. Feb 1984;39(2):69-82, 87-8. [Medline].

  33. Pelly TF, Santillan CF, Gilman RH, Cabrera LZ, Garcia E, Vidal C, et al. Tuberculosis skin testing, anergy and protein malnutrition in Peru. Int J Tuberc Lung Dis. Sep 2005;9(9):977-84. [Medline].

  34. Prendiville JS, Manfredi LN. Skin signs of nutritional disorders. Semin Dermatol. Mar 1992;11(1):88-97. [Medline].

  35. Roongpisuthipong C, Sobhonslidsuk A, Nantiruj K, Songchitsomboon S. Nutritional assessment in various stages of liver cirrhosis. Nutrition. Sep 2001;17(9):761-5. [Medline].

  36. Ryan AS, Goldsmith LA. Nutrition and the skin. Clin Dermatol. Jul-Aug 1996;14(4):389-406. [Medline].

  37. Schneider JB, Norman RA. Cutaneous manifestations of endocrine-metabolic disease and nutritional deficiency in the elderly. Dermatol Clin. Jan 2004;22(1):23-31, vi. [Medline].

  38. Shah S, Kannikeswaran N, Kamat D. A rash. Clin Pediatr (Phila). Sep 2007;46(7):650-4. [Medline].

  39. Soni BP, McLaren DS, Sherertz EF. Skin lesions in nutritional, metabolic and heritable disorders: cutaneous changes in nutritional disease. In: Fitzpatrick's Dermatology in General Medicine. Vol 2. 1999:1725-37.

  40. Tirmentajn-Jankovic B, Dimkovic N. [Simple methods for nutritional status assessment in patients treated with repeated hemodialysis]. Med Pregl. Sep-Oct 2004;57(9-10):439-44. [Medline].

  41. Wilmer WA, Magro CM. Calciphylaxis: emerging concepts in prevention, diagnosis, and treatment. Semin Dial. May-Jun 2002;15(3):172-86. [Medline].

Further Reading

Keywords

PEM, kwashiorkor, malignant malnutrition and infantile pellagra, marasmus

Contributor Information and Disclosures

Author

Noah S Scheinfeld, MD, JD, FAAD, Assistant Clinical Professor, Department of Dermatology, Columbia University; Consulting Staff, Department of Dermatology, St Luke's Roosevelt Hospital Center, Beth Israel Medical Center, New York Eye and Ear Infirmary; Private Practice
Noah S Scheinfeld, MD, JD, FAAD is a member of the following medical societies: American Academy of Dermatology
Disclosure: Nothing to disclose.

Coauthor(s)

Anusuya Mokashi, MS, Medical Student, New York Medical College
Disclosure: Nothing to disclose.

Andrew Lin, MD, FRCPC, Associate Professor, Department of Internal Medicine, Division of Dermatology, University of Alberta
Andrew Lin, MD, FRCPC is a member of the following medical societies: American Academy of Dermatology and Royal College of Physicians and Surgeons of Canada
Disclosure: Nothing to disclose.

Medical Editor

Michelle Pelle, MD, Clinical Assistant Professor, Division of Dermatology, Department of Medicine, University of California at San Diego
Michelle Pelle, MD is a member of the following medical societies: American Academy of Dermatology, California Medical Association, Medical Dermatology Society, and Pennsylvania Medical Society
Disclosure: Nothing to disclose.

Pharmacy Editor

David F Butler, MD, Professor of Dermatology, Texas A&M University College of Medicine; Director, Division of Dermatology, Scott and White Clinic; Director Dermatology Residency Training Program, Scott and White Clinic
David F Butler, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, American Society for Dermatologic Surgery, American Society for MOHS Surgery, Association of Military Dermatologists, and Phi Beta Kappa
Disclosure: 3M Pharmaceutical Grant/research funds Other; Graceway Pharmaceuticals Grant/research funds Other

Managing Editor

Jeffrey J Miller, MD, Associate Professor, Department of Dermatology, Penn State University, Milton S Hershey Medical Center
Disclosure: Nothing to disclose.

CME Editor

Catherine Quirk, MD, Clinical Assistant Professor, Department of Dermatology, Brown University
Catherine Quirk, MD is a member of the following medical societies: Alpha Omega Alpha and American Academy of Dermatology
Disclosure: Nothing to disclose.

Chief Editor

William D James, MD, Paul R Gross Professor of Dermatology, University of Pennsylvania School of Medicine; Vice-Chair, Program Director, Department of Dermatology, University of Pennsylvania Health System
William D James, MD is a member of the following medical societies: American Academy of Dermatology and Society for Investigative Dermatology
Disclosure: elsevier Royalty Other; american college of physicians Honoraria Other

 
 
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