Laboratory Studies
No laboratory studies are needed to make the diagnosis of infantile acropustulosis. A complete blood cell count often shows eosinophilia. Cultures and smears help to rule out an infectious etiology.
Histologic Findings
A unilocular, subcorneal, or intraepidermal pustule containing polymorphonuclear neutrophils or eosinophils is characteristic in infantile acropustulosis. Papillary dermal edema and a mild perivascular, mostly lymphocytic, infiltrate in the dermis may be present.[6] Direct immunofluorescence results are negative.
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