eMedicine Specialties > Dermatology > Pediatric Diseases

Albright Syndrome: Follow-up

Author: Noah S Scheinfeld, MD, JD, FAAD, Assistant Clinical Professor, Department of Dermatology, Columbia University; Consulting Staff, Department of Dermatology, St Luke's Roosevelt Hospital Center, Beth Israel Medical Center, New York Eye and Ear Infirmary; Private Practice
Contributor Information and Disclosures

Updated: Dec 11, 2009

Follow-up

Further Outpatient Care

  • Endocrinology follow-up care for McCune-Albright syndrome (MAS) patients is lifelong.
  • Ablation of hyperfunctional endocrine tissue should be arranged early.
  • Patients with MAS have an increased incidence of breast cancer and osteosarcoma, and they require lifelong follow-up screening.

Prognosis

  • With control of severe metabolic/endocrine abnormalities, patients achieve normal height and fertility.
  • In general, patients achieve a normal life span. Sudden cardiac death has been reported in a few severely affected patients.

Patient Education

  • MAS is not hereditary, and offspring of affected patients are not at an increased risk.

Miscellaneous

Medicolegal Pitfalls

  • Consider MAS in any patient with a metabolic/endocrine disorder and CALMs.
  • Expand screening laboratory tests to cover multiple possible endocrine disorders.
 
Acknowledgments

The authors and editors of eMedicine gratefully acknowledge the contributions of previous author, D. Stanton Whittaker Jr, MD, to the development and writing of this article.



More on Albright Syndrome

Overview: Albright Syndrome
Differential Diagnoses & Workup: Albright Syndrome
Treatment & Medication: Albright Syndrome
Follow-up: Albright Syndrome
Multimedia: Albright Syndrome
References
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Further Reading

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Keywords

Albright syndrome, McCune-Albright syndrome, Albright's syndrome, café au lait macules, CALMs, cafe au lait macules, cafe-au-lait macules, polyostotic fibrous dysplasia, PFD, endocrine dysfunction, precocious puberty, MAS, PPP

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Contributor Information and Disclosures

Author

Noah S Scheinfeld, MD, JD, FAAD, Assistant Clinical Professor, Department of Dermatology, Columbia University; Consulting Staff, Department of Dermatology, St Luke's Roosevelt Hospital Center, Beth Israel Medical Center, New York Eye and Ear Infirmary; Private Practice
Noah S Scheinfeld, MD, JD, FAAD is a member of the following medical societies: American Academy of Dermatology
Disclosure: Optigenex Consulting fee Independent contractor

Medical Editor

Eleanor E Sahn, MD, Director, Division of Pediatric Dermatology, Associate Professor, Departments of Dermatology and Pediatrics, Medical University of South Carolina
Eleanor E Sahn, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, and Southern Medical Association
Disclosure: Nothing to disclose.

Pharmacy Editor

Richard P Vinson, MD, Assistant Clinical Professor, Department of Dermatology, Texas Tech University School of Medicine; Consulting Staff, Mountain View Dermatology, PA
Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Association of Military Dermatologists, Texas Dermatological Society, and Texas Medical Association
Disclosure: Nothing to disclose.

Managing Editor

Van Perry, MD, Assistant Professor, Department of Medicine, Division of Dermatology, University of Texas Health Science Center
Van Perry, MD is a member of the following medical societies: American Academy of Dermatology and American Society for Laser Medicine and Surgery
Disclosure: Nothing to disclose.

CME Editor

Catherine M Quirk, MD, Clinical Assistant Professor, Department of Dermatology, University of Pennsylvania
Catherine M Quirk, MD is a member of the following medical societies: Alpha Omega Alpha and American Academy of Dermatology
Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD, Director, Department of Dermatology, Geisinger Medical Center
Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology
Disclosure: Nothing to disclose.

 
 
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