X-Linked Ichthyosis Treatment & Management

Updated: Jun 22, 2016
  • Author: Camila K Janniger, MD; Chief Editor: Dirk M Elston, MD  more...
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Treatment

Medical Care

Topical keratolytics, emollients, and hydrating agents are used to reduce scaling associated with X-linked ichthyosis [16] Topical retinoids may be beneficial. In a small study, the topical receptor-selective retinoid tazarotene was efficacious.

Patients often choose to use no therapy, although appearance-conscious adolescents and young adults may be eager and willing to treat themselves.

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Surgical Care

In cases with cryptorchidism, consider surgical intervention if spontaneous descent has not occurred by age 1 year.

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Consultations

An ophthalmologist may detect corneal opacities. An obstetrician should be involved for higher risk delivery in future pregnancies.

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Long-Term Monitoring

Address the risk for testicular carcinoma by monitoring X-linked ichthyosis (XLI) patients with periodic physical examinations.

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