eMedicine Specialties > Dermatology > Pediatric Diseases

Acute Hemorrhagic Edema of Infancy: Multimedia

Author: Mark A Crowe, MD, Assistant Clinical Instructor, Department of Medicine, Division of Dermatology, University of Washington School of Medicine
Contributor Information and Disclosures

Updated: Sep 25, 2009

Multimedia

Large cockade (rosette or knot of ribbons), annul...
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Media file 1: Large cockade (rosette or knot of ribbons), annular, or targetoid purpuric lesions found primarily on the face, ears, and extremities are characteristic of acute hemorrhagic edema of infancy.
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Large cockade (rosette or knot of ribbons), annul...

Large cockade (rosette or knot of ribbons), annular, or targetoid purpuric lesions found primarily on the face, ears, and extremities are characteristic of acute hemorrhagic edema of infancy.

The left leg in this patient with acute hemorrhag...
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Media file 2: The left leg in this patient with acute hemorrhagic edema of infancy is markedly more edematous than the right leg.
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The left leg in this patient with acute hemorrhag...

The left leg in this patient with acute hemorrhagic edema of infancy is markedly more edematous than the right leg.

Leukocytoclastic vasculitis and fibrinoid necrosi...
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Media file 3: Leukocytoclastic vasculitis and fibrinoid necrosis is seen in patients with acute hemorrhagic edema of infancy. This histologic pattern also is seen in Henoch-Schönlein purpura, although patients with Henoch-Schönlein purpura usually have immunoglobulin A deposition, and immunoglobulin A deposition is demonstrable in only approximately one third of patients with acute hemorrhagic edema of infancy (hematoxylin and eosin, magnification X40).
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Leukocytoclastic vasculitis and fibrinoid necrosi...

Leukocytoclastic vasculitis and fibrinoid necrosis is seen in patients with acute hemorrhagic edema of infancy. This histologic pattern also is seen in Henoch-Schönlein purpura, although patients with Henoch-Schönlein purpura usually have immunoglobulin A deposition, and immunoglobulin A deposition is demonstrable in only approximately one third of patients with acute hemorrhagic edema of infancy (hematoxylin and eosin, magnification X40).

This toddler with acute hemorrhagic edema of infa...
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Media file 4: This toddler with acute hemorrhagic edema of infancy has a discoloration in the area of the umbilicus similar to that described as Cullen sign.
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This toddler with acute hemorrhagic edema of infa...

This toddler with acute hemorrhagic edema of infancy has a discoloration in the area of the umbilicus similar to that described as Cullen sign.

Note the concentric arcs of purpura on the patien...
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Media file 5: Note the concentric arcs of purpura on the patient's arm.
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Note the concentric arcs of purpura on the patien...

Note the concentric arcs of purpura on the patient's arm.

Despite the frightening appearance of purpura in ...
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Media file 6: Despite the frightening appearance of purpura in these patients, they usually are in no significant distress.
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Despite the frightening appearance of purpura in ...

Despite the frightening appearance of purpura in these patients, they usually are in no significant distress.

More on Acute Hemorrhagic Edema of Infancy

Overview: Acute Hemorrhagic Edema of Infancy
Differential Diagnoses & Workup: Acute Hemorrhagic Edema of Infancy
Treatment & Medication: Acute Hemorrhagic Edema of Infancy
Follow-up: Acute Hemorrhagic Edema of Infancy
Multimedia: Acute Hemorrhagic Edema of Infancy
References
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References

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Further Reading

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Keywords

acute hemorrhagic edema of infancy, AHEI, acute infantile hemorrhagic oedema, Finkelstein's disease, Seidlmayer syndrome, , cockade purpura with edema, postinfectious cockade purpura of early childhood, acute benign cutaneous leukocytoclastic vasculitis of infancy

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Contributor Information and Disclosures

Author

Mark A Crowe, MD, Assistant Clinical Instructor, Department of Medicine, Division of Dermatology, University of Washington School of Medicine
Mark A Crowe, MD is a member of the following medical societies: American Academy of Dermatology and North American Clinical Dermatologic Society
Disclosure: Nothing to disclose.

Medical Editor

Daniel J Hogan, MD, Clinical Professor of Internal Medicine (Dermatology), NOVA Southeastern University; Investigator, Hill Top Research, Florida Research Center
Daniel J Hogan, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Contact Dermatitis Society, and Canadian Dermatology Association
Disclosure: Nothing to disclose.

Pharmacy Editor

Richard P Vinson, MD, Assistant Clinical Professor, Department of Dermatology, Texas Tech University School of Medicine; Consulting Staff, Mountain View Dermatology, PA
Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Association of Military Dermatologists, Texas Dermatological Society, and Texas Medical Association
Disclosure: Nothing to disclose.

Managing Editor

Jeffrey J Miller, MD, Associate Professor of Dermatology, Penn State University College of Medicine; Staff Dermatologist, Penn State Milton S Hershey Medical Center
Jeffrey J Miller, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, Association of Professors of Dermatology, North American Hair Research Society, and Society for Investigative Dermatology
Disclosure: Nothing to disclose.

CME Editor

Joel M Gelfand, MD, MSCE, Medical Director, Clinical Studies Unit, Assistant Professor, Department of Dermatology, Associate Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania
Joel M Gelfand, MD, MSCE is a member of the following medical societies: Society for Investigative Dermatology
Disclosure: AMGEN Consulting fee Consulting; AMGEN Grant/research funds None; Genentech Consulting fee Consulting; Centocor Consulting fee Consulting; Centocor Grant/research funds None; Covance Consulting fee Consulting; Shire  Consulting

Chief Editor

Dirk M Elston, MD, Director, Department of Dermatology, Geisinger Medical Center
Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology
Disclosure: Nothing to disclose.

 
 
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