Werner Syndrome Treatment & Management

Updated: Jun 13, 2016
  • Author: Camila K Janniger, MD; Chief Editor: Dirk M Elston, MD  more...
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Treatment

Medical Care

Specific treatment for Werner syndrome (WS) does not exist. Only symptomatic treatment of related disturbances is recommended. Results of a 2010 study on mice suggest that vitamin C supplementation could be beneficial for patients with WS. [19]

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Consultations

Consultations are related to the concomitant diseases.

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Complications

Complications of Werner syndrome (WS) are related to the concomitant diseases and symptoms described above (see Physical). Pregnancy complicated by the presence of Werner syndrome has been reported. [20]

The variant genotype of WRN Leu1074Phe has been associated with a 1.36-fold significantly increased risk of breast cancer in Chinese women, particularly pronounced in those carrying Phe/Phe genotype and having an earlier age at menarche, to produce a 3.58-fold increased risk of breast cancer. [21]

Patients with Werner syndrome may develop severe cystoid macular edema after laser therapy. [22]

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