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Dermatologic Manifestations of Menkes Kinky Hair Disease Differential Diagnoses

  • Author: Suguru Imaeda, MD; Chief Editor: William D James, MD  more...
Updated: Sep 26, 2014

Diagnostic Considerations

Child abuse (based on skeletal radiographic findings)

Argininosuccinic aciduria

Björnstad syndrome

Crandall syndrome

Salti-Salem syndrome

Tay syndrome

Conradi-Hünermann chondrodysplasia punctata

Bazex syndrome


Hypohidrotic ectodermal dysplasia

Ankyloblepharon-ectodermal defects - Cleft lip and/or palate

Salamon syndrome

Arthrogryposis and ectodermal dysplasia

Ectodermal dysplasia with syndactyly

Tricho-odontonychial dysplasia with pili torti

Pili torti and enamel hypoplasia

Differential Diagnoses

Contributor Information and Disclosures

Suguru Imaeda, MD Chief of Dermatology, Yale University Health Services; Chief of Dermatology, Veterans Affairs Connecticut Healthcare System; Assistant Professor, Department of Dermatology, Yale University School of Medicine

Suguru Imaeda, MD is a member of the following medical societies: American Academy of Dermatology, American Medical Association, Connecticut State Medical Society, Sigma Xi, Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Specialty Editor Board

Michael J Wells, MD, FAAD Associate Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine

Michael J Wells, MD, FAAD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, Texas Medical Association

Disclosure: Nothing to disclose.

Robert A Schwartz, MD, MPH Professor and Head of Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, Rutgers New Jersey Medical School; Visiting Professor, Rutgers University School of Public Affairs and Administration

Robert A Schwartz, MD, MPH is a member of the following medical societies: Alpha Omega Alpha, New York Academy of Medicine, American Academy of Dermatology, American College of Physicians, Sigma Xi

Disclosure: Nothing to disclose.

Chief Editor

William D James, MD Paul R Gross Professor of Dermatology, Vice-Chairman, Residency Program Director, Department of Dermatology, University of Pennsylvania School of Medicine

William D James, MD is a member of the following medical societies: American Academy of Dermatology, Society for Investigative Dermatology

Disclosure: Nothing to disclose.


Mark A Crowe, MD Assistant Clinical Instructor, Department of Medicine, Division of Dermatology, University of Washington School of Medicine

Mark A Crowe, MD is a member of the following medical societies: American Academy of Dermatology and North American Clinical Dermatologic Society

Disclosure: Nothing to disclose.

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Classic menkes kinky hair disease in an 8-month-old male infant.
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